Best cbd oil for acne scars

The Best CBD Creams & Topicals for Acne (March 2022)

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Early research on CBD’s benefits for acne, eczema, and other skin issues is promising (3).

Unfortunately, finding the right topical CBD product for acne can be difficult. The market is filled with thousands of products, many of which contain less CBD than they should, carry contaminants, or aren’t strong enough to provide an effect.

That’s why we compared dozens of CBD creams, balms, and other topical products based on their formula, third-party lab test results, hemp quality, potency, customer reviews, price, and other criteria.

Here are the best CBD creams and other topical CBD products for acne.

Table of Contents

Top 5 Best CBD Creams & Topicals for Acne

  1. Best Overall:CBDistillery CBDefine Cream | full review
  2. Best Value: Lazarus Naturals CBD Balm | full review
  3. Best Balm: CBDfx Calming Balm Stick | full review
  4. Best Formula: CBDMEDIC Acne Cream | full review
  5. Travel Size: PlusCBD Balm | full review

CBD Terminology

  • Terpenes: aromatic plant compounds with a wide variety of beneficial properties (1).
  • Minor cannabinoids: CBN, CBG, and other beneficial cannabinoids found in smaller amounts than CBD. For hemp, THC also counts as a minor cannabinoid.
  • Hemp: non-intoxicating cannabis variety with high CBD and low THC levels (less than 0.3%).
  • Full-spectrum: whole-plant hemp extract containing multiple cannabinoids, terpenes, and flavonoids. This form of CBD is about 4 times more potent than pure CBD (2).
  • Broad-spectrum: whole-plant hemp extract similar to full-spectrum CBD, but with THC removed (may contain trace amounts).
  • CBD isolate: pure CBD with all other hemp compounds removed.

CBDefine Skin Care Cream (Best Overall)

CBD Potency 17.6 mg/g
Volume 28.4 g
Total CBD 500 mg
Cost per mg CBD $0.10
Type Full-spectrum
Third-Party Test View report

Use coupon code CBDTHINKER for 15% off

Pros:

  • Full-spectrum CBD
  • Additional anti-acne ingredients
  • U.S. Hemp Authority-certified

Cons:

  • Only one strength

Our top choice for acne goes to CBDistillery’s skincare cream. It contains 500 mg of full-spectrum CBD, so you’re getting the complete benefits of hemp. It also has other natural compounds that can help with inflammation and acne, including tea tree oil and hemp seed oil.

CBDistillery’s third-party tested cream is derived from organic hemp cultivated in Colorado, the unofficial center of the American hemp industry. It’s certified by the U.S. Hemp Authority, which means adherence to strict hemp production standards.

This cream costs $0.10 per mg of CBD. Compared to other CBD topicals on the market, this price is considered below-average.

Founded in 2016, CBDistillery is a popular Colorado brand known for its high quality and transparency.

Lazarus Naturals CBD Balm (Best Value)

CBD Potency 50 mg/g
Volume 20-60 g
Total CBD 1000-3000 mg
Cost per mg CBD $0.01-0.02
Type Full-spectrum
Formulas 3
Third-Party Tests View report

Pros:

  • Unbeatable value
  • Full-spectrum CBD
  • USDA-certified organic hemp source

Cons:

  • Lacks additional active ingredients

If you’re looking for the best value, we recommend the full-spectrum CBD balm from Oregon’s Lazarus Naturals.

It costs only $0.01–0.02 per mg of CBD. Not only is this one of the lowest prices on the market but it also comes with the quality that Lazarus Naturals is known for.

This balm contains 1000-3000 mg of full-spectrum CBD plus standard skincare ingredients such as beeswax and mango butter. It’s also one of the most potent CBD topicals available, providing 50 mg CBD per gram.

Although you don’t necessarily need a high-potency CBD product for acne, this does mean you can use smaller doses to get even more value.

Lazarus Naturals is an employee-owned company and directly grows its hemp in Central Oregon — a rarity among CBD companies. It also provides comprehensive third-party test reports directly on each product page to confirm the safety and potency of its products.

CBDfx Calming CBD Balm Stick (Best Balm)

CBD Potency 12.5-50 mg/ml
Volume 60 ml
Total CBD 750-3000 mg
Cost per mg CBD $0.03-0.05
Type Broad-spectrum
Third-Party Test View report

Use coupon code TAKE15 for 15% off

Pros:

  • Additional anti-acne ingredients
  • Excellent price

Cons:

  • Not a full-spectrum CBD product

One of America’s top CBD brands, CBDfx is our go-to pick for an anti-acne balm. It contains 750 or 3000 mg of pure CBD in a 2 oz (60 ml) jar.

Each balm stick includes all-natural skincare ingredients that can moisturize, reduce inflammation, and help with other acne symptoms, including tea tree oil, lavender, and chamomile.

This balm is derived from organic Kentucky hemp. Like all CBDfx products, it undergoes comprehensive third-party testing to verify its safety and potency, with the results available online.

CBDfx’s calming balm costs only $0.03-0.05 per mg of CBD. Relative to other CBD topicals, that’s an exceptionally low cost.

CBDMEDIC Acne Treatment Medicated Cream (Best Formula)

CBD Potency 5 mg/g
Volume 40 g
Total CBD 200 mg
Cost per mg CBD $0.15
Type Broad-spectrum
Third-Party Test View report

Use coupon code CWEB10 for 10% off

Pros:

  • Contains anti-acne salicylic acid and other anti-acne compounds
  • Made specifically for acne

Cons:

  • Need product batch number to view third-party test report

This cream from CBDMEDIC has an impressive anti-acne formula. It contains 200 mg of broad-spectrum CBD alongside 1% salicylic acid, one of the most reliable anti-acne ingredients out there (4).

It also carries other natural compounds that can help with acne, including bentonite, tea tree oil, and zinc.

This cream is sourced from organic American hemp and tested by a third-party lab to verify its CBD content. It costs $0.15 per mg of CBD. Considering that you’re also getting salicylic acid, that’s a good price point for a CBD topical.

CBDMEDIC is part of Charlotte’s Web, one of the oldest and most reputable CBD brands in the industry.

PlusCBD CBD Balm (Travel-Size)

CBD Potency 3.8 mg/g
Volume 12 g (0.4 oz)
Total CBD 45 mg
Cost per mg CBD $0.33
Type Full-spectrum
Third-Party Test View report

Use coupon code FIRST20 for 20% off

Pros:

  • Full-spectrum CBD
  • Added ingredients that can help with acne

Cons:

For those who want a product they can use on the go, PlusCBD Oil’s hemp stick is a great option. This balm is made with 45 mg of full-spectrum CBD and other ingredients that can reduce inflammation and help with acne, such as sweet almond oil and white willow bark.

PlusCBD’s travel-size balm costs $0.33 per mg of CBD, which is a bit pricey. But it makes sense since the product is small and contains many added ingredients.

One of the first companies to offer CBD products in the U.S., PlusCBD is known for its scientific approach. It tests all of its products in-house in addition to third-party testing.

On top of that, it’s one of the only CBD brands that holds both self-affirmed Generally Recognized as Safe (GRAS) status and U.S. Hemp Authority Certification, two programs that highlight high quality manufacturing standards.

How We Choose CBD Products

Here are the key criteria we use to choose the best CBD creams and other CBD products.

Look for Third-Party Tested Brands

Third-party testing is the best way to confirm the efficacy and safety of CBD products. These tests are done by an independent laboratory that checks whether a given product carries as much CBD as it says on the label.

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Third-party tests can also look for the presence of pesticides, heavy metals, and other contaminants that may be harmful to the skin.

In this day and age, all reputable CBD companies utilize third-party testing and share the test results publicly on their websites. A lack of these tests is a big red flag.

Check the Hemp Source

CBD comes from hemp, which means the plant quality and cultivation process are important. The best American hemp is organic and grown in one of three states: Colorado, Kentucky, and Oregon.

European countries are also an excellent source of hemp because many have been growing it continuously for centuries.

It’s even better if the company grows and extracts its hemp directly instead of buying it from another producer or uses USDA-certified organic hemp. You can find all of this info on the company website.

Choose Full-Spectrum CBD When Possible

As we highlighted at the beginning of the article, there are three main types of CBD: isolate, full-spectrum, and broad-spectrum.

If you want to get the best effects out of a CBD product for acne or any other health issue, it’s best to use a full-spectrum or broad-spectrum product because they contain multiple cannabinoids, terpenes, and other beneficial hemp compounds.

Whole-plant CBD products benefit from the cannabis “entourage effect” — the combined effects of all these compounds working together in synergy, rather than CBD by itself (2).

Buying Guide for CBD Products for Acne

In this section, we’ll cover everything you need to know about topical CBD products and how they can help with acne.

What is CBD?

Cannabidiol (CBD) is one of over 121 compounds called cannabinoids found in the cannabis plant. Unlike tetrahydrocannabinol (THC) — the cannabinoid most of us are familiar with — CBD is non-intoxicating. That means it doesn’t get you high.

That’s why many people are using CBD-based products to benefit their health without any of the mind-altering effects of cannabis. CBD can provide numerous health benefits ranging from reducing anxiety to alleviating seizures.

What are CBD Topicals?

Unlike CBD oil, topical CBD products are designed to be used directly on the skin. They can’t penetrate deep enough to reach the bloodstream, so they’re highly unlikely to cause any side effects.

CBD topicals come in many forms, including lotions and creams, balms and salves, oils and serums, and even cleansers. Although these products can have different uses, they all work as a way of applying CBD to your skin for beneficial effects.

Aside from CBD, topicals often contain many of the same natural, beneficial ingredients you’d see in standard skincare products. These can include common substances such as:

  • essential oils, like lavender and peppermint oil
  • shea and cocoa butter
  • beeswax
  • coconut oil
  • aloe vera
  • vitamin E

Also, CBD topicals designed specifically for acne can contain popular anti-acne ingredients such as salicylic acid and charcoal. The precise ingredient list will vary depending on the product.

What is Acne?

Also known as acne vulgaris, acne is a skin disorder characterized by pimples (blackheads and whiteheads), oily skin, and scarring. Acne occurs as a result of your hair follicles becoming clogged with dead skin cells and oil.

Acne usually appears on the face, but can also occur on your chest, shoulders, back, and other parts of the body. It can happen in people of all ages, although teenagers are the most commonly affected group.

Health experts estimate that acne affects about 9.4% of the world population, making it the 8th most prevalent disease (5).

The causal factors of acne include:

  • Overproduction of sebum, the oily substance produced by your sebaceous glands to lubricate the skin
  • Inflammation of sebocytes, the skin cells that make up the sebaceous glands
  • Overgrowth of Cutibacterium acnes bacteria

Acne can be treated with a wide variety of approaches, including drugs and dietary changes. However, standard treatments are not always effective and can cause significant side effects.

CBD and Acne: The Research Evidence

Research into CBD’s anti-acne effects has only just begun. However, the findings are promising and suggest that CBD can help with acne in several ways.

One 2019 study looked at the effects of a CBD-infused gel in people with psoriasis, eczema, and scars from acne and these two conditions. The researchers found that CBD alleviated psoriasis symptoms, reduced scars and blemishes, and improved measures of skin health such as elasticity and hydration (6).

Meanwhile, the researchers of a 2014 study applied CBD to human sebocytes, skin cells that produce the oily sebum implicated in acne.

They found that CBD lowered inflammation, the production of new sebocyte cells, and the secretion of sebum, three processes involved in causing acne (7). The researchers concluded that “CBD has potential…for the treatment of acne vulgaris.”

How Does CBD Help With Acne?

As noted by the study above, CBD can improve acne by reducing inflammation and the production of sebum. It achieves this by interacting with the body’s endocannabinoid system (ECS) (8).

This system helps our bodies maintain a healthy state of balance called homeostasis. To do so, it regulates key processes, such as pain, immune function, sleep, mood, appetite, and digestion.

The ECS and its receptors are present in every part of the body, including the skin. Research suggests that it plays an important role in skin health by regulating inflammation, skin cell growth, and other processes (9).

CBD supports healthy endocannabinoid system function by reducing the breakdown of anandamide, one of the two main endocannabinoid made by our bodies (10).

Another way CBD can fight acne is through its antimicrobial properties (11). There’s some evidence that overgrowth of Propionibacterium acnes and other skin bacteria is involved in acne (12).

Are CBD Topicals Safe?

CBD is considered a generally safe compound with few and minor side effects (13).

More importantly, because CBD cannot penetrate the skin effectively enough to reach the bloodstream, topical products are unlikely to cause drowsiness or other side effects that can occur with ingested products such as tinctures.

Having said that, it’s possible to experience an allergic skin reaction from other ingredients present in CBD topicals, such as terpenes.

Topical CBD Dosage for Acne

Topical CBD products can range in potency from as little as 0.5 mg of CBD per ml to as high as 20 mg/ml.

There isn’t enough research to suggest the ideal dosage of CBD for acne. Furthermore, the dose can depend on multiple factors, such as the severity of your symptoms and the formulation you’re using.

As such, the best approach is to start with the dose recommended by your product, assess the effects, and gradually increase until you start experiencing the desired effects.

Topicals vs. Other CBD Products

There are some key differences between topicals and other types of CBD products:

  • Application: Topicals are applied to the skin rather than taken internally.
  • Effects: The effects of topicals are felt in the area applied rather than the whole body (14).
  • Onset time: Topicals typically start working within minutes and their effects can last about as long as tinctures.
  • Dosage: Topicals are harder to dose because you can’t measure the amount as easily as other methods.
  • Price: Topicals tend to cost more than most other CBD products, especially if you use a specialized, multi-ingredient product like a lotion.
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How To Apply CBD Topicals for Acne

As with any skincare product, you can apply a CBD topical directly to the area of skin affected by acne pimples or scarring. Make sure the area is clean and dry and massage the product into the skin for best results.

It’s best to start with a small amount and see if you achieve the desired effects. You can always apply more later if needed or use a higher dose next time.

Can Topical CBD Cause a Failed Drug Test for THC?

As noted above, it’s highly unlikely that a topical CBD product containing THC will cause you to fail a drug test. That’s because cannabinoids cannot effectively penetrate the skin to reach the bloodstream.

However, research in this area is still ongoing. If you don’t want to take any risks, it’s best to use products made with CBD isolate (pure CBD) or broad-spectrum CBD.

Can You Apply Regular CBD Oil to Acne?

You can also apply regular CBD oil to your skin to help with acne and other conditions. However, this won’t produce the best results because it’s meant to be taken sublingually (under the tongue).

Summing Up: CBD for Acne

Our top pick for the best CBD cream for acne is the CBDefine skincare cream from CBDistillery. It’s full-spectrum, contains other anti-acne ingredients, made by one of the most reputable CBD brands, and comes at an affordable price.

If you’re interested in trying out CBD for acne we recommend using a topical product rather than a sublingual CBD oil. Topical CBD products act directly on the skin area they’re applied to, which is the best way to combat acne.

As an added benefit, you don’t need to worry about any side effects because CBD is highly unlikely to reach the bloodstream when applied to the skin.

References

Gleb is a freelance writer from Vancouver, Canada specializing in CBD and cannabis. He’s read thousands of studies on CBD and other supplements, helping him translate complex science into plain language. Gleb has tried and reviewed dozens of CBD brands and products, written third-party testing reports, and knows the CBD industry inside and out. When not writing, he likes to kickbox, travel, and tell everyone how awesome intermittent fasting is.

CBD Oil For Acne: Everything You Need to Know

Bryan is a contributing writer for Byrdie covering all things beauty and grooming. He has over 16 years of experience in beauty editorial and has been with Byrdie since 2020.

Rachel is a board-certified dermatologist and Assistant Clinical Professor at Mount Sinai Hospital Department of Dermatology. She has contributed to Byrdie, as well as Harpers Bazaar, Marie Claire, Allure, Vogue, and the New York Times, and more

Madeline has been with Byrdie and Brides since 2021. Most recently, she lead social media at Glamour magazine where she covered pop culture, beauty, and fashion.

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In This Article

CBD oil is seeping into virtually every beauty product category nowadays—even in deodorant and toothpaste. With its anti-stress, antioxidant, and anti-inflammatory claims, it’s no wonder this so-called “wonder ingredient” is pushing its way into our self-care routines. Even more, according to the latest studies, CBD oil may be exactly what your breakout-prone, irritated skin needs to get back into shape.

Although there’s still a great deal of required research ahead to determine how best to use CBD to treat acne, we talked to a panel of experts, including cosmetic chemist Ron Robinson of BeautyStat, Michele Green, board-certified dermatologist, Kenneth Howe of Wexler Dermatology, and Rachel Nazarian of the Schweiger Dermatology Group to get the facts as well as the potential of using CBD oil for acne.

Keep reading to determine if CBD’s antioxidant, anti-inflammatory, and oil-regulating properties actually work wonders for acne.

Meet the Expert

  • Ron Robinson is a cosmetic chemist at BeautyStat. is a board-certified dermatologist based in Manhattan.
  • Kenneth Howe is a board-certified dermatologist at Wexler Dermatology.
  • Rachel Nazarian is a New York City-based dermatologist at Schweiger Dermatology Group.

Type of Ingredient: Antioxidant, anti-inflammatory, sebum-regulating.

Main Benefits: Reduces inflammation, healing and calming, regulates oil production, neutralizes free radicals.

Who Should Use It: It is recommended for those looking to treat mild to moderate inflammatory acne lesions at home. It’s also great for sensitive or those allergic to typical anti-acne ingredients, such as benzoyl peroxide or retinol.

How Often Can You Use It: Products containing CBD oil can be used twice per day as part of your usual anti-acne skincare routine.

Works Well With: Ingredients designed to calm skin and decrease inflammation, including arnica, hyaluronic acid and ceramides.

Don’t Use With: Ingredients that can counteract the anti-inflammatory benefits of CBD, such as alcohol. Also, be aware that CBD is still an unregulated ingredient, and ongoing research is still exploring CBD’s pathways and other ingredients it may or may not work well with.

What is CBD Oil?

CBD—which stands for Cannabidiol—oil is a compound derived from both hemp (cannabis sativa) and marijuana (cannabis sativa indica) plants, both of which are part of the cannabis family. When it comes to acne’s root causes—a combination of bacteria, oil, and dry skin cells getting trapped in your pores—CBD oil seems to have all bases covered. “CBD oil is beneficial to these conditions due to its anti-inflammatory and antioxidant properties. It reduces sebum production and is also antimicrobial, so it works great for acne-prone skin,” says Green. She also cited a 2007 study published in the Journal of Dermatological Science that showed CBD oil applied to the skin may inhibit the overproduction of keratinocytes (skin cells), thus eliminating yet another acne-causing culprit.

Benefits of CBD Oil for Acne

  • Reduces inflammation: CBD oil helps soothe irritation caused by acne, noticeably reducing overall redness and making breakouts appear smaller and less painful. This is especially helpful for acne-prone skin sensitivity, as CBD oil works without the dryness, redness, or irritation of conventional ingredients.
  • Controls oil production: “The most exciting finding of CBD oil is that it’s ‘sebostatic’—it cuts down on oil production in the skin,” says Howe. “Current evidence suggests the skin has its own endocannabinoid system, which is to say cannabinoids are active in the skin, binding to their receptors, and signaling for certain activities to occur or not occur.” How does that relate to oil production? Green explained that “the increase in sebum production is a result of endogenous cannabinoids (anandamide and 2AG) which are produced in the sebaceous glands. These endogenous cannabinoids act on CB2 receptors inhibiting the lipogenic action, therefore regulating sebum production.”
  • It’s an antioxidant: CBD oil is packed with potent antioxidants that help protect skin from free radicals resulting from environmental damage and improve texture and tone over time. While none of the dermatologists could vouch for CBD oil’s ability to fade post-acne marks, it could provide an extra measure of antioxidant protection into your anti-acne routine.
  • Acne multi-tasker: Rather than act as a spot treatment, acne-targeting products containing CBD oil may help manage the overall issues that contribute to acne formation. Nazarian says, “Because it works as both an anti-inflammatory and can decrease oil production, it has the ability to multitask as an acne product. It may be considered a gentler option and a safe option for many different skin types.”
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Other Skin Benefits

One thing worth pointing out about incorporating CBD oil into your skincare routine is how kind it is to skin. “It’s gentle, and that’s what makes it stand out from other options,” said Nazarian. “Additionally, there are many skin types that are either too sensitive to use ingredients such as benzoyl peroxide or retinol on, or they have allergies to these ingredients. Having an additional tool in the ‘acne toolkit’ will always be useful in the fight for healthy skin.”

Side Effects of CBD Oil

Though rare, the known side effects of using CBD oil for acne include dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue. CBD oil is also known to interact with certain medications such as blood thinners. While there are no known interactions with other topical products, you should start with a patch test if you’re concerned about a reaction. If you experience irritation, it’s a pretty safe bet that you’re sensitive to CBD oil, and you should stop using it.

How to Use It

When it comes to actually using CBD oil to treat acne, you may find yourself wondering: supplement or product? Nazarian says, “The evidence supporting use of CBD in treating acne is purely topical at this point. Use of CBD was tested topically on skin cells and has shown promise. Oral supplementation or smoking of CBD formulations has not been evaluated in this manner and can not be recommended.”

The good news is, there’s no shortage of CBD-laced products. One of the most popular routes is face oil. Oils are still having their moment in skincare, as they’re ideal for virtually every skin type (depending on the formulation) and act as an excellent carrier for a variety of potent compounds—like CBD. Oils are also easy to incorporate into a multiple-step skincare regimen, so if you’re looking to up your anti-acne game with an extra product that has very little likelihood to interact with your existing products, a face oil containing CBD oil might be the perfect fit. There are also various cleansers, creams, lotions, and oils for the face and body, but it’s important to steer clear of any that might contain potential comedogenic ingredients.

While the doctors we spoke to were happy to recommend products, they were also quick to remind us that CBD is still an unregulated ingredient, making it difficult to gauge a product’s efficacy. There’s no way to specify the purity or optimal percentage of active ingredients required for the product to be effective.

The Best Products with CBD Oil for Acne

“This product packs a 100mg hemp oil lightweight formulation which also contains adaptogens” (plant-based roots and herbs that help calm our body’s reaction to stress), says Green.

This anti-blemish cream combines 200mg of CBD hemp extract with 1% salicylic acid to calm and soothe active breakouts and clear up blemishes, blackheads, and whiteheads while keeping skin smooth and hydrated.

These concentrated patches will help you forget everything you knew about spot treatments that dry zits into painful oblivion. It is packed with the ideal ratio of salicylic acid and hemp to reduce inflammation and speed healing, while hydrocolloid action stops the infection in its tracks.

Each scoop of these luxe bath salts contains approximately 20mg of CBD oil and a host of other de-stressing and body-boosting ingredients, including pink Himalayan salt, arnica, Epsom salts, and calendula. Plus, they get two thumbs up from Nazarian, who praises their ability to decrease inflammation and encourage relaxation. Great for a bacne-busting soak—make sure the water isn’t too hot.

When cleansing broken-out skin, it’s important to be thorough while still respecting the skin’s moisture barrier. While this refreshing gel cleanser doesn’t contain actual CBD oil, it’s stacked with Cannabis Sativa seed and green oregano oils.

The skin around the eye area is the thinnest and most delicate on the face, so while an eye cream isn’t exactly first on the list of anti-acne products, one containing CBD could tick off two essential boxes of your skincare regimen: eye care and soothing anti-acne action.

Rather than applied topically, a few drops of this ultra-pure, ultra-potent CBD oil taken each day orally may help balance out the stress levels and reduce inflammation.

CBD oil is an antioxidant that reduces inflammation, controls oil production, and manages the overall issues that contribute to acne formation.

Yes, it’s especially beneficial for acne-prone skin. “It’s gentle, and that’s what makes it stand out from other options,” said Nazarian. “Additionally, there are many skin types that are either too sensitive to use ingredients such as benzoyl peroxide or retinol on, or they have allergies to these ingredients. Having an additional tool in the ‘acne toolkit’ will always be useful in the fight for healthy skin.”

Nazarian says, “The evidence supporting use of CBD in treating acne is purely topical at this point. Use of CBD was tested topically on skin cells and has shown promise. Oral supplementation or smoking of CBD formulations has not been evaluated in this manner and can not be recommended.”

Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable and trustworthy.

Burstein S. Cannabidiol (Cbd) and its analogs: a review of their effects on inflammation. Bioorg Med Chem. 2015;23(7):1377-1385.

Oláh A, Markovics A, Szabó-Papp J, et al. Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment. Exp Dermatol. 2016;25(9):701-707.

Baswan SM, Klosner AE, Glynn K, et al. Therapeutic potential of cannabidiol (Cbd) for skin health and disorders. Clin Cosmet Investig Dermatol. 2020;13:927-942.

Wilkinson JD, Williamson EM. Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis. Journal of Dermatological Science. 2007;45(2):87-92.

Palmieri B, Laurino C, Vadalà M. A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars. Clin Ter. 2019;170(2):e93-e99.

Atalay S, Jarocka-Karpowicz I, Skrzydlewska E. Antioxidative and anti-inflammatory properties of cannabidiol. Antioxidants (Basel). 2019;9(1):E21.

Huestis MA, Solimini R, Pichini S, Pacifici R, Carlier J, Busardò FP. Cannabidiol adverse effects and toxicity. Curr Neuropharmacol. 2019;17(10):974-989.

Casiraghi A, Musazzi UM, Centin G, Franzè S, Minghetti P. Topical administration of cannabidiol: influence of vehicle-related aspects on skin permeation process. Pharmaceuticals (Basel). 2020;13(11):E337.

Lu J, Cong T, Wen X, et al. Salicylic acid treats acne vulgaris by suppressing AMPK/SREBP1 pathway in sebocytes. Exp Dermatol. 2019;28(7):786-794.

Crippa JA, Guimarães FS, Campos AC, Zuardi AW. Translational investigation of the therapeutic potential of cannabidiol (Cbd): toward a new age. Front Immunol. 2018;9:2009.