Best CBD Oil for Anxiety and Depression in 2022: Top 5 CBD Oil Brands
CBD’s capacity to help us cope with stress and anxiety is one of the most researched and scientifically validated benefits. CBD has been demonstrated to affect serotonin levels in the body and appears to replicate many of the effects of antidepressants, but without the adverse side effects.
As a result, CBD oil has become very popular, and it may be the best option for your anxiety problems. However, CBD products are widely available on the market, which could make it difficult to choose the right one for your needs.
As a result, we have compiled a list of the best CBD oils for anxiety from the top brands in the industry.
After reading this article, you will be armed with a plethora of useful information, and you will be able to choose the best CBD oil for anxiety comfortably.
Top 5 Best CBD Oil & Tinctures In 2022:
: Overall Best CBD Oil for Anxiety & Depression; Editor’s Choice Most Potent CBD Oil for Anxiety : Preferred CBD Oil Dosage for Anxiety : CBD Oil & Tincture for Stress Relief : Highly Rated CBD Oil for Depression
Here are the detailed reviews of our top picks:
#1. Exhale Wellness: Overall Best CBD Oil for Anxiety & Depression; Editor’s Choice
Exhale Wellness is our top recommendation, as it is a well-known CBD brand that is available on a variety of platforms. Overall, it seeks to improve people’s lifestyles by providing high-quality CBD products. So, if you are looking to acquire the best CBD oil, Exhale is the place to go.
Its headquarters are in Los Angeles, California, and it has extensive experience in this industry. Some of the top CBD products on the market are grown, extracted, and manufactured by this company. Moreover, Exhale’s products are designed to provide users with a healthier approach to living a better life and improving their well-being.
The company believes nature contains the secret to good health and wellness, and as such, it has become their philosophy in developing CBD products. As a result, we recommend their full-spectrum CBD oil as the most refined option for anxiety reduction. Furthermore, the oil contains a whole spectrum of cannabinoids.
The full-spectrum CBD oil comes in an easy-to-use glass dropper bottle and in two potency options — 600mg and 1,200mg. It can be readily purchased from their official website, and if you choose the subscribe and save option, you will receive a 25% discount.
Exhale Wellness collaborates with Colorado farms to obtain organic hemp that is grown locally. The hemp used to make CBD extracts is of the highest quality and comes from an organically produced hemp plant that is grown under rigorous quality control norms and laws.
Advanced Extraction Method
The company obtains CBD extracts from full-spectrum hemp using the CO2 extraction process, which is the most advanced and the best method. The CBD oil is also subjected to stringent quality control procedures during the manufacturing process.
- Third-party lab tested
- 18-month shelf life
- Transparent about manufacturing processes
- U.S.-grown, organic hemp
- Wide range of products
- Free shipping on all orders
- 30-day money-back guarantee
- Only available for purchase online
Our research and consumer feedback shows that Exhale’s CBD oil is the most potent in the market. Aside from its strength, the CBD oil has quick-acting effects, making the brand number one on our list.
Customers will find it easy to make purchases on the site because it is incredibly user-friendly. The company also employs industry-standard production procedures and testing to assure quality and safety, along with offering user-friendly policies to all customers.
#2. BudPop: Most Potent CBD Oil for Anxiety
BudPop is now one of the most well-known brands on the market. The company has released several high-quality CBD products, and customers have reacted positively. Moreover, BudPop’s CBD oil is pure, as it contains no unnecessary ingredients.
This CBD oil is offered in two flavors — Peppermint and Natural — and it comes in a glass bottle dropper with a 30ml capacity. Each bottle contains 1,500mg of CBD, and each serving contains 50mg of CBD. The oil’s contents are listed on the packaging, and all of the ingredients are natural and organic.
Furthermore, BudPop’s products are sent to a third-party lab, which checks them for toxins and additives. As a result, customers receive the best goods of the finest quality. You can also get discounts on the products if you bundle them with other BudPop products.
BudPop’s high-quality products have received glowing reviews from customers online, on social media, and in several high-profile publications.
In addition, BudPop’s lab-tested goods adhere to all authorized manufacturing methods, including federal requirements that ensure safe and pure lab-tested products produced entirely of non-GMO, vegan, and organic components.
Shipping & Customer Service
BudPop is quickly establishing a reputation for providing excellent customer service and a high level of client satisfaction. When a product refund is required, they provide it quickly and contact their consumers in a courteous, friendly, and prompt manner. Moreover, free shipping is available on all orders.
- Third-party lab tested
- Superior quality CBD oil
- Easily available lab reports
- 30-day money-back guarantee
- Free shipping
- Only available on the official website
Many individuals have compared BudPop’s CBD oil to other brands and found it superior. BudPop’s CBD oils are said to have unrivaled taste and effectiveness. Furthermore, several users have stated that the top CBD oils have aided them in dealing with daily stress.
After using this product, one customer even claimed he could now tell the difference between highly potent and less effective CBD oils, and as a result, he is now a regular customer at BudPop.
#3. Hollyweed CBD: Preferred CBD Oil Dosage for Anxiety
Hollyweed’s staff consists of wellness-oriented individuals with extensive experience in the medical cannabinoid sector. These individuals believe in the beneficial properties of hemp and are working to develop products that reflect their beliefs. When it comes to CBD oil, Hollyweed is our third recommendation for you to consider.
Hollyweed’s CBD oil is made using an ultra-clean CO2 extraction technique. After extracting the full-spectrum CBD, they combine it with pure hemp seed oil. As a result, you get a soothing and tranquil CBD boost by putting a few drops on your tongue or by combining it with food and drink.
Hollyweed’s oil has been lab tested and is kept in a glass dropper bottle. Because it contains less than 0.3% delta-9 THC, it does not provide a psychoactive effect. Moreover, this CBD oil is both safe and effective, as natural, organic, and non-GMO ingredients are used in every recipe.
Because most brands lack consistency and transparency, Hollyweed has used various methods to gain each customer’s trust by ensuring their entire satisfaction and general wellness. If one thing sets them apart, it is their sincerity. Each product is made with carefully chosen ingredients that reflect the brand’s work ethic and credibility.
Hollyweed CBD oil provides a calming and relaxing effect on the central nervous system, which may encourage deeper, more natural sleep. Furthermore, it may also lessen the symptoms of anxiety and stress.
CO2 Extraction Method
Hollyweed uses the cutting-edge and ultra-clean CO2 extraction technique to create CBD oil. Their team combines full-spectrum CBD oil with high-quality hemp seed oil to generate full-spectrum CBD oil.
- Third-party lab tested
- Excellent for calming and relaxing the mind
- Non-GMO and gluten-free
- Free of any additives
- Full-spectrum oil
- Long-lasting effects
- High potency
- Free shipping
- 30-day money-back guarantee
- Only available for purchase online
We conducted extensive research and examined all social media reviews, as well as the leading review sites, to provide you with a comprehensive assessment of the brand’s overall rating.
We noticed a lot of positive feedback regarding the oil’s potency, with many customers stating they could feel the desired results in a short period. Customers also appreciate the products’ packaging and the brand’s comprehensive website detailing all of the products it sells.
#4. Cheef Botanicals: CBD Oil & Tincture for Stress Relief
Cheef Botanicals sources and manufactures its products through a network of Colorado farmers. The company was founded because the owners saw a gap in California’s health-conscious, plant-based cannabis products.
The organization maintains stringent quality control at every level and uses organic procedures. Cheef Botanicals also has their products verified for quality and accuracy by third-party labs. Cheef Botanicals offers a collection of vegan-friendly, plant-based, one-of-a-kind organic items, which are non-GMO, gluten-free, cruelty-free, and dairy-free.
Artificial flavors and colors are not used in any of the products, and a 30-day money-back guarantee is also available from the company. Cheef Botanicals’ CBD oil comes in four distinct quantities, with 300mg being the smallest and 3,000mg being the largest. Aside from that, you can get the products as a bundle and save money.
Cheef Botanicals fills a need in plant-based medicine for health-conscious people. CBD products from Cheef Botanicals are legal in all 50 states across the United States, and all items are eligible for free shipping.
Cheef Botanicals’ CBD oil was created using a CO2 extraction technology that is entirely natural. They have developed the most potent concentrated oil that is simple to take and delivers rapid benefits. The drops have no flavor and are placed under the tongue for quick absorption into the bloodstream.
This product is composed entirely of natural ingredients and will not cause you to become inebriated. The CBD oil is non-GMO, organic, and free of chemicals and preservatives. The bottle comes in various sizes, including 300mg, 600mg, 1,200mg, and 3,000mg.
Furthermore, if you sign up for their newsletter, you will receive a 25% discount on your first purchase.
- All-natural and organic
- No additives or preservatives
- Non-GMO and dairy-free
- Four sizes available
- Provides immediate effects
- High potency
- 30-day money-back guarantee
- Free shipping
- Larger bottles are more costly
If you are looking for a natural CBD health supplement to help with anxiety, Cheef Botanicals’ CBD oil is your best alternative. It will perform significantly better than any other item due to its organic and natural structure.
You may notice a noticeable improvement in your overall health as well as the efficiency with which your body performs. This CBD oil may also help you sleep better, along with providing other beneficial effects.
#5. FAB CBD: Highly Rated CBD Oil for Depression
FAB CBD has been busy working since 2017, delivering clients high-quality, clean, and unique CBD products. In truth, the brand’s CBD oils for anxiety are powerful and outstanding. FAB CBD’s team has extensive experience in the health and wellness industry, which is one of the main reasons for the company’s success.
The brand’s objective has always been to offer the safest, most effective CBD products so customers can live a healthy lifestyle. When it comes to developing its award-winning CBD products, the brand has never strayed from its rigorous set of criteria.
FAB CBD offers full-spectrum CBD oils in various concentrations and natural tastes, and there are five different tastes and four different sizes to choose from. In addition, the hemp used by FAB CBD is all organic and produced and harvested in Colorado.
The brand’s pure and strong hemp extracts are extracted using the CO2 extraction method, which is widely used in the industry. This procedure ensures all extracts are pure and devoid of contaminants. As a result, the cannabinoids, terpenes, and phytonutrients in FAB CBD’s products are all healthy.
FAB CBD sources all of the organic hemp it utilizes in its high-quality products from Colorado. The hemp is cultivated and harvested utilizing cutting-edge cloning and growth technology, which ensures it is clean, potent, and devoid of pesticides, herbicides, and other toxic chemicals.
Third-Party Lab Testing
ProVerde Labs, an independent third-party lab, regularly tests every product that FAB CBD makes. Transparency is also important to the brand, which is why the brand posts each lab test report on its website for customers to view.
- Top-notch, kind, and knowledgeable customer support
- Third-party lab tested
- Shipping is quick and secure
- Free shipping on orders of $99 or more
- 30-day money-back guarantee
- No options for auto-ship or subscription
Customers claim FAB has the greatest CBD oil on the market. They appreciate that this company offers flavored CBD oils, making them easier to swallow. Some users claimed to have received multiple benefits.
We also enjoy that the brand’s website contains a lot of information about the products, along with being simple to navigate. Many customers appreciate both the packaging and the potency of FAB CBD’s oil.
Factors to Consider While Buying CBD Oil for Anxiety
CBD oils are derived from hemp, as can be observed. But, for hemp to be effective and safe to use, it must be of high grade. As a result, it is critical to look for hemp products grown organically on farms in the United States. You should probably look for another brand if a company does not disclose information about the hemp they utilize.
It is also vital to inspect the oil’s complementing ingredients to ensure it is all-natural and does not contain any potentially harmful synthetic compounds. If you are searching for diversity, seek products that offer it, such as ones that come in various flavors.
The potency of a CBD oil is another key element to consider before purchasing it. The potency will tell you how much CBD is in the product and how many milliliters of oil it contains.
You should be aware that a higher potency does not necessarily imply that the oil will be more effective for you. Lower amounts have been shown to help some people; therefore, a 250mg CBD oil bottle may suffice for your pain.
As a beginner, you should start with a small dose and gradually raise it as your tolerance develops. However, keep in mind that dose varies depending on the person’s metabolism, tolerance level, and consumption mode. Each person is unique, and if you exceed your dosage limit, you may experience minor adverse effects.
CBD oil comes in both unflavored and flavored varieties. The unflavored version is the simpler of the two, and regardless of CBD or THC concentrations, natural CBD oils and hemp extracts have an earthy, musky flavor.
If you plan to mix it with food or drinks, a product with flavoring may be preferable. Some manufacturers add a dash of lime, organic coconut oil, or berry juice for a delightful finish. Even a modest amount of flavor can dramatically improve the acceptability of CBD oil.
The fact that the products have been tested or not is a critical issue to consider as well. This is because third-party testing assures quality, safety, and potency.
You can also examine the hemp source, components utilized, oil strength, and other vital information if a manufacturer has given lab test findings on their website. It is not a good sign if a brand does not disclose lab testing reports on its website.
The manner of extraction is equally crucial, and CO2 extraction is the gold standard. It is utilized as a solvent to convert a solid state to a liquid by entering the plant and extracting the cannabinoids.
The CO2 will then disappear, leaving an oily, sticky extract behind. On the other hand, alternative extraction procedures include olive oil or alcohol.
If you want to understand if a product is worth buying, read the reviews first. One of the most crucial elements to consider is the customer experience. People are always willing to share their stories, and they are always brutally honest.
You can quickly assess whether a product is worth buying or not based on their statements. Each company’s website has a section for reviews, so scroll down and read what others have to say. If most of the comments are positive, the product is likely of great quality.
There will be negative feedback because the product will not work for everyone. You can base your decision on your requirements and previous customer experiences. The evaluations will also provide sufficient information about the company’s service, which is important for final decisions.
You can also ask friends who have tried the product for the most up-to-date information, and you can request that they let you test out their product to see if it works for you and whether or not it will be beneficial.
It is usually preferable to have fewer components in CBD oil, as it should only include CBD and a high-quality carrier oil. Some CBD oil companies additionally include natural flavors as a third ingredient.
If there are too many ingredients in the best CBD oils for anxiety, it is no longer pure and may not be as effective. Because some people dislike the flavor of hemp, improving the taste of CBD is beneficial. As a result, some brands turn to flavoring their CBD products.
There are hundreds of CBD natural extracts available, making it difficult to choose the ideal one for your anxiety or depression. Investing effort in researching ingredients can make a huge difference. To do so, you must first grasp the distinctions between CBD and hemp seed oils.
Both of these are made from hemp. The difference is that hemp oil is extracted from the seed and does not contain cannabidiol, whereas CBD oil is extracted from the leaves and contains a variety of cannabinoids. The amount of CBD in each extract varies, with broad-spectrum CBD being THC-free and full-spectrum CBD including trace quantities of THC.
Cannabinoids interact to create an entourage effect, which is one of the most critical advantages of full-spectrum CBD. It is thought that taking all industrial hemp plant parts together is more beneficial than taking them separately, and CBD with a broad spectrum of effects provides more targeted alleviation for specific depression and anxiety symptoms.
Other Benefits To Buy CBD Online:
CBD has been found in scientific research to help alleviate pain by interacting positively with the body’s endocannabinoid process to minimize inflammation.
- Alleviate Cancer-Related Symptoms
CBD has been shown to help with cancer treatment side effects such as vomiting, discomfort, and nausea.
CBD has been demonstrated to be an effective treatment for neurological illnesses such as multiple sclerosis and epilepsy. It has also been shown to have neuroprotective properties.
CBD is also beneficial for one’s heart health. For example, nine healthy men were given 600mg CBD oil in one study, and researchers found their resting blood pressure lower.
Anxiety, sadness, coffee, medicine, medical ailments, and some environmental factors like loud noises or a bad mattress, for example, can all disrupt your sleep-wake pattern.
CBD improved sleep while also lowering anxiety disorders and social anxiety in a 2019 study. A total of 72 people were administered CBD every day for the duration of the study. 79.2% reported less anxiety in the first month, and 66.7% reported improved sleep.
FAQs: CBD Oil for Stress & Anxiety
Q1. Why should you use CBD oil instead of conventional medicine?
CBD oil is not designed to cure or treat anxiety, and it should not be used as a substitute for prescription medications or your existing treatment plan. Always consult with your doctor to identify the best course of action for your generalized social anxiety disorder and other diagnoses.
Many individuals appreciate CBD products because they help them relax, particularly during stressful situations, and also because they help them fall asleep sooner and remain asleep longer. Traditional drugs have a long list of adverse effects, and while they might help with generalized anxiety disorder, they can also make people feel disconnected and numb.
CBD helps alleviate the unpleasant feelings associated with anxiety disorders while also helping you stay present and enjoy the good things in life. Each person must select which form of assistance is best for them. Overall, CBD is gaining a good reputation, making it worthwhile for many to try.
Q2. What is the recommended dose of CBD oil for Post Traumatic Stress Disorder?
There is no one-size-fits-all solution for determining how much CBD oil to ingest. To begin with, everyone is unique. To attain the same potential advantages as someone twice their weight, a 150-pound individual needs substantially less CBD.
It is also crucial to think about CBD oil’s composition. Full-spectrum cannabidiol, for example, comprises a wide range of components that can have a stronger effect than broad-spectrum cannabidiol.
On the other hand, CBD isolate is a kind of pure cannabidiol that gives the best pound-for-pound outcomes. Therefore, you should only take a small quantity. Start with 5-10mg of CBD each serving as a general rule, and check the label if you are not sure how much that is. CBD products are labeled to indicate how much cannabidiol is in a single serving.
Q3. What is the difference between CBD oil and CBD tincture?
A tincture is often a solution made by steeping herbs in an ethanol solution to produce a concentrated liquid containing the herb’s active components. Oil is any liquid extract of a herb generally mixed with a carrier oil such as MCT oil. The terms tincture and oil are almost interchangeable in the CBD market for the most part.
Q4. Is CBD addictive?
According to the latest WHO studies, CBD does not cause habit-forming or addictive effects.
Above, we discussed the best CBD oil for anxiety disorders that has proven to be effective in assisting people in overcoming their anxiety disorders. We believe that having this knowledge will aid you in determining which brand to purchase.
All of the brands we have featured have done exceptionally well in the CBD industry, and we are confident their CBD oil will not disappoint you. If you are unsure whether CBD oil should be added to your current supplement regimen, talk to your primary care doctor or a medical professional.
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Best CBD Oil for Anxiety: How CBD Helps with Stress & Depression
We all experience anxiety at one point or another.
Roughly 40 million Americans are diagnosed with clinical anxiety disorders every year, and countless others experience some form of anxiety on a daily or weekly basis. This anxiety can take a toll on our lives — affecting our relationships, performance at work or school, and our overall health and wellbeing.
One of the most popular alternative support options among anxiety sufferers is cannabidiol (CBD) — a non-psychoactive cannabinoid found in the hemp plant. This compound works through two main systems to promote a feeling of calmness and relaxation.
In this article, we’ll explain how CBD is suggested to support anxiety, what the research says, and offer some of the best hemp oil options for anxiety.
- Rated #1 for overall anxiety and depression relief
- Highest quality hemp oil on our list
- 100% organic, free of pesticides, and artificial ingredients
- Established brand with 24/7 customer support
- 30-day 100% money-back guarantee
- Good customer support
- 30-day money-back guarantee
10 Best CBD Oils for Anxiety (Top Quality Brands of 2022)
- Best Overall Pick: Royal CBD
- Best Organic Formula: Gold Bee
- Runner Up: CBD Pure
- Good Customer Support: Hemp Bombs
- Veteran Brand: CBDistillery
- Most Socially Responsible: NuLeaf Naturals
The CBD market hasn’t yet matured — which means there are a ton of brands offering inferior quality products. They’re managing to remain in business on hype alone. As the market matures, these companies won’t last — leaving only the best brands in the wake.
At this early stage in the market, it’s important that customers understand how to spot a good CBD manufacturer, and which companies to avoid.
To make things easier for you, I’ve compiled a shortlist of the best CBD oils I’ve come across for anxiety. Let’s cover each one in more detail before we go on to discuss exactly how CBD is reported to help with anxiety.
1. Royal CBD
Get 15% off all Royal CBD products. Use code “CFAH” at checkout.
|Total CBD Content||250 – 2500 mg|
|Available Flavors||Berry, Vanilla, Mint, Natural|
|Potency||8.3 – 83.3 mg/mL|
What We Like About Royal CBD Oil:
Royal CBD is a California-based CBD brand with a growing collection of reviews from both regular users and industry experts.
Unlike many of its competitors, Royal CBD doesn’t rely on far-fetched claims in their marketing. The company also doesn’t specialize in gimmicky product types like we’ve seen from numerous other brands recently. The Royal CBD assortment is all about the classics. They keep it simple, focusing on full-spectrum CBD oil, THC-free CBD gummies, capsules, and CBD-infused topicals.
Royal CBD uses organically-grown hemp from the finest farms in California and Colorado. The company makes this CBD oil by first making a full-spectrum hemp extract using supercritical CO2. The extract is then dissolved in high-grade MCT oil and some flavorings to make the oil more enjoyable to use.
This CBD oil comes in 250 mg, 500 mg, 1000 mg, and 2500 mg – with the option of berry, mint, or other natural flavors.
I personally use Royal CBD’s 1000 mg full-spectrum CBD oil for my general anxiety disorder (GAD) & social anxiety. I should note that I tried 27 other brands before finding the one I liked!
With a 90-day, no-questions money-back guarantee – the only thing you have to lose your anxiety.
- Extremely potent (83mg of CBD per serving for 2500 mg bottle)
- Contains the full spectrum of phytocannabinoids
- Made from 100% natural ingredients
- Third-party tested for potency & purity
- 90-day 100% money-back guarantee
- No CBD vape oils available from the company
- Only comes in a full-spectrum extract
2. Gold Bee – Best Organic Formula
|Total CBD Content||1200 mg|
|Available Flavors||Natural, Kiwi-Honey|
Gold Bee specializes in full-spectrum CBD oil that combines organic hemp with honey sourced from the Brazillian Rainforest. If not for the lack of high-potency oils, we would place this brand on the very top of our ranking due to the quality of ingredients it offers.
The full-spectrum extract is suspended in hemp seed oil to boost its bioavailability and keep everything in the cannabis family. Every product from Gold Bee’s line up is rigorously tested in third-party laboratories for their CBD content and purity. Unlike competitor brands, Gold Bee doesn’t use artificial flavorings and sweeteners in its products. The kiwi version of the oil is flavored with the said honey.
I use CBD oils for my morning anxiety when I can’t get my mind wrapped around my daily duties, and I’ve never been calmer since then. The 1200 mg potency also provides a nice dose of CBD before bed; I take it to unwind after spending most of the day in front of a computer screen, and I noticed a big difference in how rested I wake up the next day.
- Premium Colorado-grown hemp
- CO2 extraction
- Contains full-spectrum CBD
- Delicious kiwi flavor
- Sweetened with organic honey
- Lab-tested for potency and purity
3. CBDPure (Runner Up)
|Total CBD Content||100 – 600 mg|
What We Like About CBDPure CBD Oil:
Similar to the other brands in our ranking, CBDPure sells full-spectrum CBD oil that has been sourced from domestically grown hemp and extracted with supercritical CO2.
If you’re looking for the highest potency, though, you might end up a little bit disappointed, as the maximum strength offered by their products is 600 mg of CBD per bottle, which is equal to 20 mg of CBD per mL. Our first choice, Royal CBD, has 30% higher potency than the strongest option available for this brand.
The good news is that these are full-spectrum extracts, so you need less CBD to find relief from anxiety than you would with CBD isolate. Each batch of CBDPure products is tested in a certified laboratory for the entire cannabinoid profile, terpenes, and flavonoids, as well as for potential contaminants.
If you’re not satisfied with this CBD oil for your anxiety, CBDPure has a 100% Satisfaction Guaranteed program, which allows you to get a full refund if you send the order back within 90 days after the purchase.
- Extracted with supercritical CO2
- Extensively tested in 3rd-party laboratories
- You can get a full refund within 90 days if you’re not satisfied with the product
- Only available as oil drops or soft gel capsules
- Low potency (20 mg of CBD/mL maximum)
- No flavored options
- They don’t ship to Arkansas, Louisiana, Indiana, and Kansas
4. Hemp Bombs
|Total CBD Content||300 – 4000 mg|
|Available Flavors||Peppermint & watermelon|
|Potency||10 – 133.3 mg/mL|
What We Like About Hemp Bombs CBD Oil:
Hemp Bombs is an American company specializing in the production of 99% pure CBD isolates. These products are available as standard tinctures, vape oils, capsules, or gummies.
Hemp Bombs CBD oil comes in five different potency options ranging from 300 mg to as much as 4000 mg of CBD per bottle. The CBD has been sourced from certified organic hemp plants from Europe and extracted with supercritical CO2 for the highest purity level.
This CBD oil option is made from CBD isolate — which means there’s nothing but pure CBD inside this oil. No THC or other cannabinoids, terpenes, or any other phytochemicals from the hemp plant. This offers a big advantage in that there’s guaranteed to be no THC in the bottle.
Isolate-based CBD oils are very versatile — you use them on their own, make DIY CBD infusions (e.g. creams and balms), add it to E-liquid for an extra punch, or use it in cooking delicious food. They’re also preferred for people who are using CBD alongside other supplements because there are fewer compounds that can potentially interact with the other health supplements.
Keep in mind that CBD isolate is purged from any cannabinoids other than CBD — so if you’re looking to take advantage of the entourage effect, you’re better off going for a full-spectrum CBD oil such as Royal CBD.
- Sourced from 100% certified organic hemp from European farmers
- Extracted with CO2
- Lab-tested for purity and potency
- Available in 5 potency options
- Less expensive than full-spectrum extracts
- Not certified organic
- No entourage effect from other cannabinoids
- The ultra-high potency options are overkill for most users
|Total CBD Content||250 – 5000 mg|
|Potency||8.3 – 166 mg/mL|
What We Like About CBDistillery CBD Oil:
CBDistillery is an industry veteran, but make no mistake, the brand hasn’t rested on its laurels. On the contrary, CBDistillery continues to set high standards for its competitors, both in terms of the quality of ingredients and the potency of its products.
CBDistillery’s CBD oil is available in five different potencies, starting from 250 mg up to 5000 mg of full-spectrum CBD. The 2500 mg and 5000 mg options come in 30 mL bottles, which breaks down to 83–166 mg per serving — that’s enough CBD to keep you supplied for weeks or months.
What I love about CBDistillery’s assortment is that its products are sold at very reasonable prices. The 250 mg CBD oil costs around $20, so you don’t have to break the bank to get yourself a high-quality health supplement.
Users can choose between full-spectrum CBD oil and THC-free (broad-spectrum) oil, which is a nice move towards those who want to keep any traces of THC away from their system without losing the benefits offered by the entourage effect.
- Sourced from non-GMO, pesticide-free hemp
- Available as full-spectrum CBD or pure CBD oil (THC-free)
- Lab-tested for the cannabinoid content and purity levels
- Available in 5 different potency options
- Good price/quality ratio
- Not certified organic
- No flavored options
6. NuLeaf Naturals
|Total CBD Content||240 – 4850 mg|
What We Like About NuLeaf Naturals CBD Oil:
NuLeaf Naturals is another veteran brand that’s been selling CBD oil for over 5 years now. While they don’t have the broadest range of CBD products — only oil drops for humans and pets — this company definitely knows how to make an all-natural CBD oil.
All Nuleaf Naturals oils are sourced from domestic hemp and extracted with CO2. NuLeaf Naturals CBD oil has a beautiful amber-gold color, which is a good indicator of its quality. The oil is then filtered to remove any remaining plant matter.
NuLeaf sells its products in five different volumes — all in the same potency of 48 mg.mL CBD:
- 5 mL — 240 mg of CBD total
- 15 mL — 725 mg of CBD total
- 30 mL — 1450 mg of CBD total
- 50 mL — 2425 mg of CBD total
- 100 mL — 4850 mg of CBD total
- Made from 100% organic, Colorado-grown hemp
- Extracted with a combination of subcritical and supercritical CO2
- Lab-tested for potency and over 200 common contaminants
- Full-spectrum extracts
- Available for both humans and pets
- Narrow product range
- More expensive than much of the competition
7. Charlotte’s Web
|Total CBD Content||200 – 1800 mg|
|Available Flavors||Mint Chocolate, Lemon Twist, Orange Blossom, Olive Oil|
|Potency||7 – 60 mg/mL|
About Charlotte’s Web:
Charlotte’s Web is one of the oldest CBD companies in the United States. Founded by the Stanley Brothers, the brand has earned its reputation for helping now late Charlotte Figi with her intractable epilepsy. Despite several controversies about the health claims they made in the past, Charlotte’s Web didn’t lower its standards and still produce some of the best hemp extracts on the market.
Charlotte’s Web CBD oil is available in several concentrations: 200 mg, 500 mg, 1500 mg, and 1800 mg of total CBD. The highest potency provides 60 mg of full-spectrum CBD in every milliliter. You can choose between two bottle sizes (30 mL and 100 mL); Charlotte’s Web also offers flavored versions of its CBD oil, such as Mint Chocolate, Lemon Twist, Orange Blossom, and Olive Oil.
The company uses ethanol for extraction instead of the standard CO2 technology, which may leave a distinct aftertaste upon swallowing.
- One of the most reputable brands on the market
- Full-spectrum CBD
- Delicious flavored versions
- Up to 1800 mg of CBD per bottle
- Available in two sizes: 30 mL and 100 mL
- Third-party tested for potency and purity
- Non-organic hemp
- Ethanol extraction
- Suspension in olive oil (bitter taste)
- The company received a warning letter from the FDA in the past due to inappropriate health claims
|Total CBD Content||300 – 7500 mg|
|Available Flavors||Natural, Berry, Orange, Mint|
|Potency||10 – 250 mg/mL|
cbdMD is a North Carolina-based company that offers a wide range of CBD products, including tinctures, gummies, capsules, topicals, bath bombs, sleep aids, and pet products.
The company boasts a broad selection of pure CBD oils. The potency of these extracts ranges between 300 and 7500 mg of CBD per bottle; the highest concentration packs a healthy dose of 200 mg of pure CBD isolate suspended in MCT oil for improved absorption. cbdMD also offers four flavor options: natural, berry, orange, and mint.
On the one hand, it could be challenging to find another company with such concentrated products; but on the other hand, these CBD oils are based on a broad-spectrum extract, which doesn’t evoke the full entourage effect. Therefore, higher potency may not translate into better results.
Transparency-wise, cbdMD provides up-to-date certificates of analysis from a third-party laboratory. They are available on the company’s website; you can find them by entering the product’s batch.
- US-grown, non-GMO hemp
- CO2 extraction
- Up to 7500 mg of CBD per bottle
- Batch-specific certificates of analysis
- Limited entourage effect due to the lack of THC
- Most people don’t need such high doses of CBD in their routine
|Total CBD Content||500 – 3000 mg|
|Available Flavors||Natural, Citrus, Mint Chocolate|
|Potency||16 – 100 mg/mL|
Medterra is a small California-based company that offers premium CBD extracts in different spectra: full-spectrum, broad-spectrum, and isolates. The potency of these oils ranges between 500 mg and 3000 mg of CBD per bottle, which is a standard range. Aside from the unflavored version, there are two flavored options: Citrus and Mint Chocolate.
The full-spectrum CBD oil is also infused with 2 mg of THC per bottle, which the company claims to be the true full spectrum of cannabinoids. However, the problem with this version of Medterra’s CBD oil is that they aren’t legal in all 50 states because they contain more than 0.3% of THC.
So, if you want to buy Medterra’s products in all 50 states, your options are limited to broad-spectrum extracts and isolates. These come in higher potencies, upwards of 1000 mg of CBD per bottle.
All of Medterra’s CBD oils are tested in a third-party laboratory for potency and purity, including the results for pesticides, heavy metals, and residual solvents.
- Premium-grade CBD oils
- Up to 3000 mg of CBD per bottle
- Available as full-spectrum CBD, broad-spectrum CBD, and isolates
- Lab tested for potency and purity
- The “real” full-spectrum CBD oil isn’t available in all states
- Some of the lab reports indicate higher CBD levels than stated on the bottle
- No discounts for returning customers
10. Joy Organics
|Total CBD Content||450 – 900 mg|
|Available Flavors||Tranquil Mint, Fresh Lime, Summer Lemon|
|Potency||15 – 30 mg/mL|
About Joy Organics:
Joy Organics is one of the most reputable CBD vendors in this space. The brand was founded by a woman named Joy Smith, who has been exploring the benefits of CBD oil for her problems with pain and sleep.
Joy Organics offers a range of broad-spectrum CBD extracts sourced from certified organic hemp. The company has plenty of positive reviews all over the internet. They also haven’t received any warning letters from the FDA yet.
The Joy Organics CBD oil is formulated with broad-spectrum CBD in a modest potency range, from 450 to 900 mg of CBD per bottle. These oils are available in three refreshing flavors: Tranquil Mint, Fresh Lime, and Summer Lemon. The highest potency provides 30 mg of CBD in every milliliter, which is a standard dose for most people in terms of daily supplementation.
In 2018, one of the company’s citrus tincture was found to contain a fungicide that is commonly used on citrus fruit during independent testing. Fortunately, Joy Organics recalled the product immediately following this and implemented a new third-party testing system.
- Non-GMO, US-grown hemp
- Supercritical CO2 extraction
- Broad-spectrum CBD
- Delicious flavors
- A bit expensive
- No high-strength oils
What is CBD Oil?
CBD, short for cannabidiol, is one of the active ingredients in the cannabis plant (Cannabis sativa). This includes both industrial hemp plants, and marijuana.
CBD is the modulator to the endocannabinoid system — a complex neurochemical network responsible for controlling various vital functions in the human body and brain. The endocannabinoid system regulates processes such as:
- Cognitive performance
- Body temperature
- Immune function
- Mood and emotion
- Hunger and satiety
CBD helps the endocannabinoid system maintain chemical balance within the body — also known as “homeostasis” or “equilibrium.” If homeostasis isn’t maintained, we become sick. Depending on which aspect of homeostasis is out of balance — the effects on the body will be very different. If our nervous system is affected, it can lead to symptoms of anxiety, stress, and emotional instability.
CBD has other effects on the body as well — the most relevant in the context of this article are its effects on a neurotransmitter called GABA — which is responsible for slowing us down when we become overstimulated. We’ll get into how this works in more detail later.
There are many different ways to use CBD — it’s added to capsules, infused in topical salves and creams, mixed into gummy candies, and added to vape oils. But by far the most popular form of the supplement is in the form of an oil. CBD oils are made by mixing the fat-soluble hemp extracts rich in CBD and other cannabinoids with an oil base — in most cases MCT oil or hemp seed oil.
Using CBD in the form of oil makes it easier to measure doses since you simply have to count the number of drops or measure the oil with the built-in dropper. Compare this to pure hemp extracts which require scales and a lot of experience to accurately measure the right dose.
Additionally, the oil content of CBD oils significantly improves the absorption rate in the digestive tract. This helps make the CBD more efficient — allowing you to use less CBD for the same level of benefits.
What Causes Anxiety?
Anxiety is defined as “an emotion characterized by feelings of tension, worried thoughts, and physical changes like increased blood pressure.” It’s a natural process developed over the course of human evolution to protect us from environmental threats like changes in our environment, exposure to predators, or other dangers. Feeling anxious helps us identify and avoid dangers that pose a threat to our health and wellbeing.
Anxiety can also become pathological — leading us to feel excessive stress and worry in situations that are not life-threatening. Modern stresses like work deadlines, relationship problems, or social expectations can all cause us to feel anxious. If this happens too often or in excessive amounts, it can cause us more harm than good.
There are many forms and levels of intensity of anxiety symptoms — including generalized anxiety disorder, panic disorder, post-traumatic stress disorder, social anxiety, insomnia, and many different phobias.
It’s wise to speak with your doctor if you experience severe anxiety attacks, or if your anxiety begins affecting your ability to live your life. There are many underlying causes for anxiety, so it’s best if a medical professional can explore some of these options to help you find the best form of treatment.
Why Are Pharmaceutical Anxiety Medications Dangerous To Our Health?
The most common form of drug treatment for anxiety is a class known as benzodiazepines. These medications bind to the GABA receptors in the brain to force electrical activity to slow down — thus alleviating the most common signs of anxiety. This works in a similar way to CBD, but is significantly stronger and more specific.
The main problem with conventional anti-anxiety medications is that they can become highly addictive — often leading to a worsening of symptoms over time as tolerance to the medications begins to form.
Here’s the problem…
You take benzodiazepines to fight anxiety and for a time it works. However, the body quickly forms a tolerance to the medication to resist its effects by removing some of the GABA receptors. Once these receptors are gone, we need more of the medication to produce the same effect. This process continues until we’ve reached the maximum dose for the drug. If the drug starts to wear off, we no longer have enough GABA receptor activity to keep our nervous system from going into hyperdrive — forcing us into a state of extreme anxiety.
The body will eventually reach a point where we require the drug just to not have an anxiety attack.
Benzodiazepines aren’t the only option, but they’re the most common. Other classes of medications used for treating anxiety have similar effects long-term.
Some examples of anti-anxiety medications include:
- Tricyclic antidepressants
Side-effects to these medications are common and can range in severity. Most of the drug classes on the list will cause tolerance in the body, as described above.
Here are some of the most severe side effects of prescription anti-anxiety medications:
- Cardiac disease
- Blurred vision
- Weight gain
With all these negatives, it’s no wonder why CBD has become such a popular alternative treatment option for anxiety and related conditions. You can check our post to know more about the risk of taking CBD with Xanax — a prescription drug that belongs to benzodiazepines medications.
Potential Benefits of CBD Oil For Anxiety
At the very beginning of the article, we mentioned that the endocannabinoid system regulates our response to fear, among many other functions.
Unlike conventional anti-anxiety treatments, CBD oil doesn’t just mitigate the symptoms of anxiety — it gets down to the root of the problem by regulating endocrine disruptions as well as the amount of anandamide in our brains — a compound aptly named the “bliss molecule.”
CBD has been shown to help with anxiety in a few different ways. While the majority of research describing how CBD works for this disorder is either preclinical or based on animal studies, there are hundreds (if not thousands) of testimonies from people who have found relief in CBD oil after failing with the conventional treatment. There are also a handful of randomized, double-blind, clinical trials conducted on the interaction as well. These are considered to be the highest form of clinical research available.
Let’s cover the mechanisms of action CBD oil uses to support anxiety levels and what the research says about this incredibly useful molecule.
1. Serotonin Receptors & Brain Activity
CBD has been shown to stimulate the 5HT1 serotonin receptors. In simple terms, this cannabinoid increases serotonin activity in the brain — which affects the transmission of electrical activity as well as mood, concentration, and sleep.
Studies have shown a direct link between the activity of serotonin as the 5HT1 and 5HT2 serotonin receptors in the central nervous system and anxiety disorders.
2. Anandamide Production — The Bliss Molecule
The next anti-anxiety effect of CBD is linked to its ability to increase the amount of the body’s natural endocannabinoids — anandamide and 2-AG. This effect is particularly prominent for anandamide in particular.
Anandamide has almost the same chemical structure as THC, the cannabinoid responsible for triggering euphoric and psychoactive effects in cannabis users.
Anandamide doesn’t cause psychoactive effects like THC, but it is closely correlated with feelings of bliss, joy, and euphoria. In contrast, lower anandamide levels are thought to result in a low mood or “overreaction” to stress and anxiety triggers.
CBD has been shown to enhance the activity of anandamide by preventing its breakdown and metabolism — ultimately leading to elevated levels of the bliss molecule in the brain.
3. Hippocampal Neurogenesis — Homeostasis & Anxiety
The hippocampus is a critical brain region tasked with controlling homeostasis in both the brain and body.
Brains scans of patients struggling with anxiety and depression often exhibit changes in the hippocampus, and successful anxiety treatment is associated with the production of new neurons (neurogenesis) in this area. Some research has shown.
It appears that CBD may stimulate the hippocampus to regenerate neurons, which could be groundbreaking for anxiety patients (5).
Current evidence suggests that severely damaged neuronal plasticity may influence suicidal behavior — so, regenerating neurons in the hippocampus is thought to reduce the chances of depressive behavior.
4. GABA Receptors — The Brake Pedals for the Brain
Earlier, we spoke about the interaction CBD has with our GABA receptors. Let’s dig into this a little more and discuss exactly how this works and how it relates to anxiety.
GABA essentially acts as the brake pedal for the nervous system. It’s used to keep our speed in check when we become agitated. If GABA isn’t doing its job effectively, we can quickly begin to speed out of control — resulting in symptoms commonly referred to as anxiety.
CBD binds to the GABA receptors in the nerve cells and makes them more sensitive to GABA. This would be like changing the brake pads on your car, so you don’t have to hit the pedal as hard to begin slowing down.
Research has shown that insufficient GABA activity is closely involved in the development of anxiety disorders. CBD has been shown to interact with the GABAa receptors in the neurons, offering a precise mechanism for its anti-anxiety benefits. Other cannabinoids in the cannabis plant have also been shown to support this process through GABA and other chemical pathways in the brain.
The Best CBD Oil For Anxiety: What to Look For
The hemp industry has proven to be a lucrative market for many companies. Still, as with so many emerging businesses, it’s a tantalizing sector for sketchy companies trying to cash in on unaware customers.
You want to steer clear of inferior CBD supplements as much as possible. Such products are often made from low-quality hemp, extracted with toxic solvents, and promise a lot more than CBD oil is capable of.
When searching for the best CBD products for anxiety online or in local stores near you, keep an eye out for the following details:
1. Hemp Source — Opt For Domestic
Hemp is an effective bio-accumulator, meaning it absorbs everything from the soil it grows in. When grown in polluted soil, the plant may accumulate heavy metals and other harmful toxins, resulting in a poor end product. Hemp grown in places like China or India is especially high in these toxic elements because of high soil contamination in the region.
If you want a high-quality CBD oil to help you deal with anxiety, look for products that have been sourced from domestically grown hemp. US farmers are subject to strict quality control standards, and the growing competition prevents them from cutting corners in their cultivation practices.
Plus, many US growers use organic growing methods even if their CBD oil is not certified organic, mainly due to the high cost of these certifications. Always ask your potential vendor how they source their plants to ensure you’re not throwing your money down the drain.
2. Extraction Method — Look For CO2 Extraction
The majority of high-quality CBD oils are extracted with supercritical carbon dioxide. This method produces a pure and highly potent product, leaving you with pure extracts free of any toxic solvent residue.
CBD tinctures, which are a bit different than CBD oil, are extracted with high-proof alcohol. Some less common extraction methods call for using olive oil, but when a company isn’t open about how it obtains its CBD extracts, that should raise a red flag because that means they probably applied some toxic solvents in the process. And what’s worse, there’s a risk these solvents weren’t completely removed after extraction.
3. Full-Spectrum Hemp vs. CBD Isolate
What do you want to achieve with your CBD oil aside from anxiety relief?
Are you aiming at maximizing your CBD dose per serving?
Or is the whole-plant synergy more important than the potency of cannabidiol?
If you want a versatile product and high doses of CBD — isolate-based CBD oil will be your best bet. On the other hand, full-spectrum extracts offer one perk that isolates users cannot achieve with their products — the entourage effect.
The entourage effect refers to the synergistic effect achieved by all active compounds in cannabis plants. Researchers suggest each of these compounds work in unison to amplify the benefits of one another, resulting in a greater therapeutic potential.
The cannabis community appears to support this concept; the Internet is full of testimonies from people who switched from isolates to full-spectrum CBD oil for anxiety because they needed lower doses to get relief.
4. Additional Ingredients
High-quality CBD oil contains two main ingredients — CBD extract and carrier oil in which the CBD is dissolved.
Additionally, CBD oil can have some natural flavorings added to mask the hemp aftertaste. Some products are infused with supplementary herbs and organic compounds to amplify the stress-relieving properties of cannabidiol — such as chamomile or melatonin.
In general, a complex formula involving hemp extract and other herbs and nutrients formulated for a specific application is going to be better overall.
5. Laboratory Testing Results
3rd-party lab testing is the ultimate way to verify the credibility of your CBD vendor.
Not only do such tests check for the potency of CBD in the final product, but they also list the entire cannabinoid profile and can detect any impurities that could compromise its quality.
If the brand actually uses premium ingredients in its CBD oil (as they claim), they should be open about their lab testing reports and list the results publicly on the company website. If these tests aren’t available, we suggest you move on to look elsewhere for a company that does this.
CBD Oil For Anxiety: Key Takeaways
As scientists conduct more research on the health benefits of CBD, we’re beginning to unlock new applications of this incredible plant-extract. One of the hottest areas in research at the moment is for the use of CBD with anxiety.
CBD oil works by interacting with the endocannabinoid to support homeostasis (balance), modulate GABA activity, and support serotonin and anandamide levels — all of which play a key role in the process of stress and anxiety.
The greatest challenge lies in finding the best CBD oil for anxiety out of the sea of fly-by-night CBD brands. As long as you know what characteristics make for an excellent CBD brand and what the red flags are for scam or poor-quality products — you should be able to find a product that suits your individual needs.
If you’re not sure where to start, I highly recommend you go with Royal CBD as your CBD oil of choice. The 1000 mg option offers the best value for money, and high-grade full-spectrum extract has served me well with my anxiety in the past.
Have you tried using CBD for anxiety? How did it work for you? Let us know in the comments!
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- A World Health Organizadon Demonstration Project. (1994). A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia. Journal of palliative care, 10(1), 14-18.
- Charney, D. S., Woods, S. W., Goodman, W. K., & Heninger, G. R. (1987). Serotonin function in anxiety. Psychopharmacology, 92(1), 14-24.
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Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
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