Best cbd oil for ibs d

Best CBD Oil for IBS

Are you considering CBD to help manage your IBS symptoms? CBD Clinicals is dedicated to answering all your questions regarding CBD oil for IBS for an improved quality of life .

Spruce 750mg Lab Grade CBD Oil
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

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Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

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Best High Potency

Spruce 2400mg Lab Grade CBD Oil
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

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Avida Full Spectrum CBD Oil Tincture 500mg
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC ( <0.3)

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cbdMD CBD Oil Tincture Natural 1500mg
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

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CBDistillery THC Free CBD Oil Tinctures
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

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Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

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Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

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Best Flavor Range

Hemp Bombs 750mg CBD Oil
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

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Best CBD Oil for IBS 2022

    Editor’s Pick Best Organic Editor’s Pick Best Seller Best Natural Alternative Best THC-Free Best Customer Rated Best Starter Best Flavor Range

Compare the Best CBD Oil for IBS in 2022

Best CBD Oil for IBS

1. Spruce 750mg Lab Grade CBD Oil
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Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
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Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
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The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
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Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
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cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
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CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
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This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
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A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
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Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

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How CBD May Help With IBS

Irritable bowel syndrome or IBS is a common gastrointestinal disorder that affects the large intestine (1) . Common symptoms of IBS include abdominal pain , cramping , gas, and bloating . Symptoms may also include diarrhea or constipation , or both.

Cannabidiol, popularly known as CBD, is a compound present in the cannabis plant. CBD does not affect one’s locomotor activity, memory, or body temperature on its own, unlike THC (tetrahydrocannabinol) (2) .

THC is the predominant psychoactive constituent of cannabis (sometimes called marijuana).

CBD and THC work with the ECS ( endocannabinoid system ), actively controlling gut homeostasis or balance. These compounds interact with the cannabinoid receptors (CB1 and CB2) found in almost every part of the body (3-4) .

The activation of CB1 receptors attenuates small and large bowel muscle tone and inhibits gastrointestinal motility (5) . Targeting CB2 receptors decreases inflammation by reducing cytokine and chemokine production from activated immune cells .

Cytokines and chemokines are signaling proteins that play a significant role in controlling inflammation (6) .

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In a study, re searchers hypothesized that CBD and THC are among the agents capable of modulating the ECS activities that may be useful to improve other IBS symptoms like motility, visceral pain, and low-grade inflammation (7) .

It is believed that plant-based cannabinoids like CBD and THC may mimic the actions of endocannabinoids (8) .

Endocannabinoids are naturally-occurring chemical substances in the body that bind to cannabinoid receptors to signal that the ECS needs to take action.

Research suggests that clinical endocannabinoid deficiency is an underlying cause of IBS , migraine , and fibromyalgia , a medical condition that triggers pain all over the body (9) .

Although there is a limited study examining how CBD may help with IBS, its activity in the ECS , may help with such a condition.

Nevertheless, more research is warranted to elucidate CBD’s efficacy on irritable bowel syndrome .

Benefits of Using CBD for IBS

Current research from the International Journal of Molecular Sciences examined how CBD and other non-psychoactive cannabinoids may help prevent and treat GI ( gastrointestinal ) disorders, including IBS (10) .

Main alterations observed in IBS include GI motility disturbances (11) . GI motility is the movement of food from the mouth through the throat, esophagus, stomach, intestines , and out of the body.

It is believed that modulation of the ECS may benefit IBS patients (12) .

A 2020 study from Frontiers in Neurosciences suggested that targeting the ECS may be a promising strategy to modulate gut motility and low-grade intestinal inflammation, improving IBS symptoms onset (13) .

Hence, researchers hypothesized that agents capable of modulating the ECS , such as CBD, may provide a potential first-line treatment for IBS patients (14) .

Another 2020 study from the journal Antioxidants examined CBD’s antioxidative and anti-inflammatory properties (15) .

One of the most predominant CBD antioxidant effects is the reduction of protein and lipid modifications (16) .

CBD may reduce lipid peroxidation, a process wherein free radicals attack lipids containing carbon-carbon double bonds, particularly polyunsaturated fatty acids (17) .

Carbon-carbon double bonds are found in naturally occurring fatty acids.

Meanwhile, polyunsaturated fatty acids include omega-3 and omega-6 fats, which are essential fatty acids that the body requires for cell growth and brain function (18) .

A study from Medical Science Monitor suggested that lipid peroxidation and alterations in the oxidant-antioxidant enzymatic system may have a significant role in the development of IBS (19) .

The findings showed that elevated lipid peroxidation levels observed in IBS patients may be explained by an increased xanthine oxidase activity and decreased antioxidant enzyme activity (20) .

Xanthine oxidase is an enzyme that generates ROS (reactive oxygen species). Meanwhile, antioxidant enzymes can stabilize or deactivate free radicals before attacking cellular components.

Studies show that CBD is an agonist of A2A (adenosine) receptors, which are G-protein coupled receptors that regulate inflammatory processes (21) .

Researchers believe that CBD may prevent oxidative stress by activating the A2A receptors (22) .

Oxidative stress refers to a phenomenon triggered by an imbalance between the production and accumulation of ROS in cells and the ability of a biological system to detoxify the reactive products.

A 2020 study mentioned that oxidative stress may be correlated to several IBS symptoms ( 23) .

In addition, a study by Ethan B. Russo, MD, suggested that cannabinoids, like CBD and THC, may help manage difficult to treat pain (24) .

IBS chronic pain is linked to alterations in bowel movement (25) . The chronic abdominal pain in IBS starts in the gut then travels to the brain, which interprets the sensation as pain.

The findings of these studies may be promising. Still, more longitudinal research is necessary to determine the benefits of using CBD for IBS.

CBD Usage Guideline for IBS

  • Inhalation
  • Ingestion
  • Sublingual (under the tongue)
  • Topical absorption
  • Transdermal (active ingredients are delivered across the skin for systematic distribution)

Ingesting CBD is a good option for individuals suffering from inflammatory bowel conditions, such as IBS or IBD ( inflammatory bowel disease ) since the compound will be delivered right to where it is needed most (27) .

CBD edibles are available in oil, gummies , and capsules.

The liver processes anything that goes into the stomach before it is used by the body (28) . This process is called first-pass metabolism.

First-pass metabolism refers to the metabolic process by which active compounds pass through the gastrointestinal system and are metabolized by the liver before they become available in the bloodstream (29) .

Cannabinoids , like CBD and THC that move through the digestive tract, are chemically distinct. Their bioavailability is usually different from those that enter the body via other delivery methods (30) .

Bioavailability is the extent to which a particular drug becomes entirely available to its intended biological destinations.

Aside from holding CBD oil under your tongue, you can add the oil to your food or beverage. Fatty foods are ideal for increasing bioavailability (31) .

A 2019 research study from the University of Minnesota hypothesized that high-fat foods may increase oral CBD absorption into the body (32) .

CBD Dosage

The FDA ( Food and Drug Administration ) has not approved CBD to treat IBS . Therefore, there is no standard CBD dosage for IBS.

However, it has been shown that mid-range doses of CBD between 10mg and 100mg daily may help with pain, inflammation, and conditions such as autoimmune disorders and inflammatory bowel syndrome (33) .

Still, make sure to consult a healthcare professional experienced in cannabis use for accurate CBD dosing . They may also suggest the types of CBD you may try for IBS or overall wellness .

How Long Does CBD Take to Help With IBS?

How long CBD takes to help with IBS depends on the route of administration used and several other factors like body weight and CBD potency.

Usually, you can feel the effects of CBD within 30 to 90 minutes via the ingestion method (34) .

How Long Will CBD Help With IBS?

How long CBD lasts to help with IBS depends on the bioavailability.

The bioavailability of CBD via the ingestion method is between 6% and 15% (35) . Depending on a person’s gastrointestinal tract , absorption can be both slow and inconsistent (36) .

How to Choose the Right CBD for IBS

CBD products are available in tinctures , vapes, edibles like gummies , and topicals like lotions.

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However, choosing the right CBD product for IBS can be challenging, given the number of CBD companies claiming to have the best CBD oil in the market.

  1. Know about the different CBD extracts. You may choose full-spectrum CBD oil , broad-spectrum CBD oil , or CBD isolates .

A full-spectrum CBD oil product contains all of the compounds of the cannabis plant , including CBD and other cannabinoids , terpenes, essential oils, and flavonoids.

A full-spectrum CBD is known to provide the entourage effect due to the presence of all these cannabis compounds. Its THC concentration is also less than 0.3% (37) .

When all the compounds work together, they induce the entourage effect.

The entourage effect is the concept wherein the biologically active compounds of cannabis work better when administered together.

Terpenes are aromatic compounds present in cannabis and many other plants.

Flavonoids are phytonutrients (plant chemicals) that have been suggested to exhibit biological activities, such as anti-inflammatory , antioxidant, and antiviral actions (38) .

  1. Support CBD brands that are transparent with their farming practices. Ensure that a third-party lab tested all their products for consistency and potency.
  1. Learn about carrier oils. Carrier oils are the products used to dilute essential oils. The most commonly utilized carrier oils for CBD include coconut oil and hempseed oil (40) .

Although most people use the terms hemp oil and hempseed oil interchangeably, they are different from each other.

Hemp oil ( a tem often used to refer to CBD oil ) is an essential oil that comes from the flowers and leaves of hemp plants .

Meanwhile, hempseed oil is made from the pressed seeds of hemp.

Hempseed oil is rich in fatty acids and nutrients. However, it does not contain CBD (41) .

The Potential Side Effects and Risks of Using CBD for IBS

  • Fatigue
  • Dry mouth
  • Reduced appetite
  • Drowsiness
  • Diarrhea

A common symptom of IBS is diarrhea (44) . Since CBD may cause diarrhea in some people, be sure to talk with your healthcare provider and ask for medical advice before trying CBD. Doing so can help you avoid unpleasant side effects .

If you are either expecting or breastfeeding, you should not take CBD.

The FDA strongly advises against the use of CBD , THC , and marijuana in any form during pregnancy or while breastfeeding (45) .

According to the FDA , traces of CBD may be transferred to babies through breast milk (46) .

In addition, an animal study from the International Journal of Andrology indicated that maternal exposure to psychoactive and non-psychoactive components of marijuana may produce long-term disruption of testicular function in male fetuses (47) .

Legality of CBD

The 2018 Farm Bill indicates that Cannabis sativa L. and other derivatives of cannabis with less than 0.3% THC content on a dry weight basis are deemed legal under federal law (48) .

Still, you must review various state laws regarding the use of CBD or medical marijuana to avoid possible legal repercussions. Remember that each state may impose different rules and regulations.

For instance, although marijuana use is legal in Colorado, individuals who take medical marijuana may still be arrested for impaired driving (49) . If they drive with five nanograms of THC per milliliter of whole blood, they can face legal charges for DUI (driving under the influence).

Moreover, individuals must keep their cannabis products within the borders of Colorado (50) . They cannot bring those items to areas like federal lands, including national parks and forests, and Denver International Airport.

Product Frequently
Asked Questions

IBS ( irritable bowel syndrome ) affects one’s digestive system (51) . IBS sufferers may have uncomfortable or painful abdominal symptoms, including diarrhea, constipation , bloating , and gas.

Other symptoms include low-grade inflammation (52) .

There is limited research on how cannabidiol can help with IBS. However, CBD is believed to have anti-inflammatory and pain-relieving effects (53-54) . These potential therapeutic benefits of CBD may help with IBS.

No evidence specifically suggests that CBD helps with IBS. However, a study indicated that agents capable of modulating the ECS, such as CBD, may provide a potential first-line treatment for IBS patients by improving symptoms like low-grade inflammation (55) .

Still, more studies are warranted to elucidate CBD’s efficacy on IBS.

No evidence exists suggesting that CBD can make IBS worse. However, one of CBD’s side effects is diarrhea (56) . Since CBD may trigger diarrhea in some people, ensure to talk with your healthcare provider before using CBD for IBS.

Your healthcare provider may suggest pain medications, fiber supplements, laxatives, or even antidepressants to relieve stress and depression that worsen IBS symptoms (57) .

However, antidepressants may interact with CBD (58) . Antidepressants use the cytochrome P450 enzyme system (59) .

The cytochrome P450 is a family of liver enzymes that metabolize about 60% of the pharmaceutical substances people consume.

At high doses, CBD may inhibit the activity of these enzymes, which may increase the effect and duration of action of prescription drugs metabolized by the cytochrome P450 (60) .

Lifestyle changes , particularly dietary changes, may help manage IBS symptoms (61) .

A low- fodmap diet or diet low in fermentable carbohydrates has also shown potential in helping IBS sufferers (62) .

In addition, a 2019 study showed that multi-strain probiotics supplemented over some time may have the potential to improve symptoms of irritable bowel syndrome (63) .

However, if you are considering using other treatments or diet therapies alongside CBD to help with IBS, be sure to talk with your healthcare provider. This is particularly necessary if you have other health conditions.

CBD is non-psychoactive (64) . Therefore, it does not cause a euphoric effect (65) . Still, using a full-spectrum CBD oil frequently may cause THC build-up in the body (66) .

An increased level of THC in the bloodstream may result in a positive drug test.

Doses between 10mg and 100mg may help with pain, inflammation, and medical conditions like inflammatory bowel syndrome (67) . Still, there is no standard CBD dosage for IBS because the FDA has not regulated it.

There is no specific study examining CBD’s safety for IBS. Although CBD is generally safe and is well tolerated in humans and animals, CBD may cause diarrhea in some people (68-69) .

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Hence, make sure to consult your healthcare provider if you are considering using CBD for IBS.

Best Way to Take CBD Oil for IBS

IBS is an uncomfortable condition that affects around 35 million people in the United States. Since many conventional treatments for IBS cause significant side effects, people who suffer from the symptoms of IBS are on the hunt for alternative treatments. In this guide, learn if CBD works for IBS, and find out the best ways to take this cannabinoid if you’re suffering from IBS symptoms.

Does CBD help IBS?

Over the last decade or so, research into CBD has accelerated at an unprecedented pace, and scientists have realized that CBD may help with a wide variety of serious conditions. While there is no definitive answer regarding whether CBD can help with IBS, a significant amount of research has been invested into this subject, and scientists continue to investigate the potential benefits of CBD when it comes to inflammatory conditions like IBS.

What’s clear is that CBD, as a derivative of the hemp plant, does not have intoxicating properties, making this cannabinoid very different from THC, which is an intoxicating and addictive substance found in the cannabis plant. Therefore, IBS patients can try CBD without worrying about intoxication or any other significant adverse effects.

What is IBS?

Irritable bowel syndrome (IBS) is an inflammatory condition that affects the colon (large intestine). The most common symptoms of irritable bowel syndrome are diarrhea and constipation, but other symptoms associated with IBS include abdominal pain, bloating, cramping, and gas. As one of the most uncomfortable conditions that can affect the digestive tract, people with IBS are constantly searching for safe, natural forms of IBS relief.

How does CBD Oil Work?

Cannabidiol (CBD) is a non-intoxicating cannabinoid that does not significantly stimulate the CB1 and CB2 receptors. These cannabinoid receptors cause the feeling of intoxication that accompanies THC use, and even though full-spectrum CBD can contain up to 0.3% THC, that’s not enough to activate your CB2 or CB1 receptors.

At the same time, CBD has a profound effect on the human endocannabinoid system, which manages a variety of essential bodily processes including digestion. Some researchers believe that endocannabinoid deficiency could be one of the primary causes of both physical and mental health conditions, suggesting that taking CBD oil could offer a wide range of beneficial effects.

What research says about CBD for IBS

As an inflammatory disease that affects the digestive system, IBS is a prime target of natural therapies that provide anti-inflammatory benefits within the digestive tract. While we cannot provide medical advice or make claims regarding the usefulness of taking CBD for any condition, we can still examine the evidence that has been accumulated regarding the use of CBD in treating IBS.

Research into CBD for Inflammation

CBD has been researched extensively for its potential antioxidant and anti-inflammatory properties. Scientists are keenly interested in determining the potential usefulness of CBD in relieving chronic inflammatory pain and the symptoms of inflammatory conditions like IBS.

Research into CBD for Gastrointestinal Conditions

Researchers have examined the potential usefulness of CBD as a natural modulator of your gut’s mucosal defense system, which plays a critical role in preventing the symptoms of IBS. Current research into the effects of CBD on the gastrointestinal (GI) tract is highly limited, but early results have been promising.

How much CBD oil should I take for IBS?

Different CBD oils contain different amounts of CBD, and each CBD ingestion method affects your body differently. If you decide to use CBD for IBS, however, you may want to start with a standard dose of 10-20 milligrams taken orally per day. In clinical studies, CBD doses as high as 1,500mg tincture which is 50mg of CBD per day have been shown to be well-tolerated in human subjects, but if you’d prefer to use CBD products as sparingly as possible, even a low dose might provide the beneficial effects you’re looking for.

How should I take CBD oil for the best results?

There are quite a few different ways you can take CBD, and some might be more effective for IBS than others:

CBD tinctures for IBS

As orally ingested CBD products, CBD tinctures deliver this cannabinoid directly into your digestive tract. Along the way, however, the CBD in your tincture will also be absorbed under your tongue, potentially limiting the amount of CBD that reaches your digestive system.

CBD capsules for IBS

CBD capsules pass down your esophagus before releasing CBD into your stomach. As a result, capsules might deliver CBD into your digestive tract more efficiently than other ingestion methods.

CBD edibles for IBS

CBD edibles are tasty and convenient, but a lot of the CBD they contain is absorbed into the lining of your mouth as you chew. IBS sufferers might be better off choosing CBD capsules instead.

CBD topicals for IBS

Water-based CBD topicals penetrate your skin and spread CBD throughout underlying tissues. However, topically applied CBD might not penetrate deeply enough to deliver significant concentrations of this cannabinoid into your digestive tract.

Can you rub CBD oil on your stomach?

When you experience abdominal pain due to irritable bowel syndrome, it’s only natural to try addressing the symptoms of this condition at their source. Oil-based CBD products, however, offer very poor skin penetration, so applying CBD oil directly to your stomach is unlikely to provide the results you desire. Use a water-based CBD topical formulation instead, or use an orally ingested CBD product that delivers this cannabinoid directly into your digestive tract.

Using CBD for IBS: The Bottom Line

There isn’t enough evidence to definitively determine whether CBD might help relieve the symptoms of IBS. What’s clear, however, is that every form of CBD is non-intoxicating and remarkably non-toxic, so there’s no reason you should avoid using CBD products as you pursue weight loss and make other lifestyle changes that might help manage IBS. Anyone who has this condition would prefer to treat IBS naturally, and IBS sufferers have nothing to lose by trying CBD oil for this uncomfortable and inconvenient condition.