Best CBD Oil For Muscle Relaxer


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Here are some tips and important information to help you choose the best cannabidiol (CBD) oils for muscle spasms and pain relief. Understanding how a CBD muscle relaxant could work for your patients first requires some knowledge of the body’s endocannabinoid system.

Compare the Best CBD Oil for Muscle Spasms in 2022

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
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No other flavors

Approximately 300 drops total


Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
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No artificial flavoring or colors

No THC-free option

Made from 100% organic and natural ingredients


The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
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Light Spearmint flavor

No other flavor

Non-THC, Non-detected in drug test


Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
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Various delicious flavors to choose from

cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options

Has vegan, organic, and gluten-free ingredients

Free shipping for this particular product within USA

World-class customer service team


cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
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60-Day Satisfaction Guarantee

Dropper is a bit shaky

Oil extracted from aerial plant parts of US grown industrial hemp

Sourced from non-GMO industrial hemp grown in the USA through natural farming practices


CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
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No other flavors

A bit pricey compared to competitors

Approximately 100 drops total


This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
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Vegan and Gluten free

Does not ship internationally

Has a third-party lab test

Wide variety of CBD strengths and sizes


A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
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Wide variety of flavors

Incomplete information about the product

Lab test results are complete

Does not ship to all international countries

30-day money-back guarantee


Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

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How CBD Helps With Muscle Spasms

Research from the European Journal of Pain indicated that cannabidiol may attenuate inflammation and pain without detrimental side effects (1) .

Cannabidiol , an active component of cannabis , works together with other cannabinoids, interacting with the body’s endocannabinoid system ( ECS ) to maintain wellness and homeostasis (2) .

Homeostasis is a process by which biological systems maintain stability while self-regulating to adapt to changing external conditions (3) .

The ECS regulates various functions, including sleep, appetite, memory, and pain. The system comprises cannabinoid receptors , CB1 and CB2, found within cells throughout the body (4) .

CB1 receptors play a significant role in pain sensation. The binding and stimulation of these receptors may reduce pain signals throughout the brain.

The human body naturally produces endocannabinoids that interact with cannabinoid receptors (5) .

However, if there is a shortage of endocannabinoids, plant-based cannabinoids , such as CBD and tetrahydrocannabinol ( THC ) may mimic their actions.

THC is the primary psychotropic congener in the cannabis plant that produces a euphoric high. On the other hand , CBD does not have psychoactive effects (6) .

Since CBD may offer pain relief , it may also help with certain conditions, such as muscle spasms .

Muscle spasms or muscle cramps are painful contractions of the muscles. Most of the time, spasms occur when one’s muscle involuntarily contracts uncontrollably ( 7 ) .

The condition ranges from mild to chronic pain . When touched, the spastic muscle may feel harder than usual (8) .

CBD’s purported anti-inflammatory and pain-relieving properties (9 ) may benefit individuals with muscle spasm.

Still, significant research must be done to determine whether CBD’s purported therapeutic effects may alleviate pain triggered by muscle spasms .

Benefits of Using CBD Oil for Muscle Spasms

CBD for Pain and Inflammation

A study from Neuropsychiatric Disease and Treatment examined how cannabinoids like CBD may help manage spasticity associated with multiple sclerosis (MS) (10) .

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The report indicated that cannabinoids may have beneficial effects on multiple sclerosis symptoms , such as spasticity and pain.

Spasticity is a condition when there is an abnormal increase in muscle stiffness that may interfere with movement. It is also associated with pain or discomfort ( 11 ) .

On the other hand, MS is a potentially disabling disease of the spinal cord and the brain ( central nervous system ) (12 ) .

The condition takes place when the immune system attacks the protective sheath that covers nerve fibers. This action stirs communication problems between the brain and the rest of the body ( 13) .

Researchers believe that , since the current treatment of multiple sclerosis is partially effective, developing a cannabinoid -derived drug may represent an alternative strategy to pursue ( 14) .

Another research explored the effects of a cannabis -based medicine (CBM) in patients with central pain due to MS ( 15 ) .

Results showed that CBM is mainly well tolerated and may effectively reduce neuropathic pain and sleep disturbance in MS patients ( 16) .

In addition, CBD and THC extract may help with the pain that is not relieved by potent opioids (17) .

Opioids are drugs used for pain management . However, they are associated with high abuse potential (18) .

Patients with multiple sclerosis have a higher risk of high blood pressure (19) . A randomized crossover study published in the JCI Insight showed that a single dose of CBD may reduce blood pressure (20) .

Still, the results from these studies are inconclusive. More longitudinal studies are recommended to determine CBD’s therapeutic benefits for muscle spasms.

CBD Oil for Muscle Relaxation

Based on a study investigating the effects of Sativex, cannabidiol has a muscle relaxant property that may help people with muscle pain ( 21) .

Sativex is an oral mucosal spray that contains CBD and THC . The treatment is used for spasticity and multiple sclerosis (22) .

How Much CBD to Take to Help With Muscle Spasms

There is no study specific to CBD dosing for muscle spasms. However, a review from Current Drug Safety showed that doses ranging from 1mg to as high as 1,500mg of CBD per day are well tolerated by humans (23) .

As a rule of thumb, the initial dose should be low amounts of CBD and then gradually increase the dosage as your system becomes used to it.

You can consult a medical professional experienced in cannabis use for more accurate dosing.

How Long Does CBD Take to Help With Muscle Spasms ?

There is no specific study indicating how long CBD takes to help with muscle spasms.

However, there are various methods to take CBD oil for chronic pain due to muscle spasms . You can opt for topicals , capsules, gummies , vape oils, and tinctures .

A study from Molecules noted that topical and transdermal delivery methods of cannabinoids have various advantages for localized symptoms, including inflammation and pain (24) .

Transdermal is a drug delivery method wherein active ingredients are delivered across the skin. This route of administration is also an attractive alternative to the oral delivery of substances (25) .

Via a transdermal method, CBD patches and gels have a duration of relief of 4 hours for gels and 8 hours or more for patches (26) .

You may use CBD topicals, such as CBD-infused salve, CBD lotion, and CBD cream, by massaging the product to the affected area. Your skin absorbs these products to target muscle pain , lower back pain , and soreness .

Some CBD topical products may have additional ingredients, such as peppermint or menthol, to provide cooling and soothing effects. CBD topicals’ effects last for 2 to 4 hours ( 27 ) .

Meanwhile, you may take CBD tinctures using the sublingual (under the tongue) method. Most CBD oil products include a calibrated dropper to dispense the oil.

The onset time of CBD tinctures via a sublingual route is 15 to 30 minutes, and the duration is 2 to 4 hours (28 ) .

You may also ingest CBD oil through edibles, such as capsules or gummies . Usually, these edibles have an onset time of 30 to 90 minutes, lasting for 6 to 8 hours (29) .

Inhaling cannabidiol using vape pens is the quickest way to benefit from the effects of CBD ( 30) . The onset time is usually 2 to 15 minutes, and the effects can be felt for 2 to 4 hours ( 31) .

However, caution is advised when vaping CBD. Vaping may irritate the lungs ( 32) .

How Long Will CBD Help With Muscle Spasms ?

There is no specific study indicating how long CBD helps with muscle spasms. Hence , how do you know which products will work best for you?

One factor you should consider is the product’s bioavailability. Bioavailability is a measure of a substance or compound’s absorption rate or how much of the consumed CBD remains available for use in the body (33) .

Bioavailability varies depending on the delivery method used. For instance, smoking or vaping CBD has a bioavailability of 17 to 44% (34 ) , which is high. However, vaping CBD may have detrimental effects on the lungs ( 35 ) .

On the other hand, CBD topicals have zero bioavailability ( 36) . Since they are not absorbed into the system like other CBD forms, they are safer to use, considering how little is known about the long-term safety of cannabidiol (37) .

How to Choose CBD Products for Muscle Spasms

Choosing a high-quality CBD product depends on different factors, including your personal preference, the severity of your condition, and the form of cannabidiol .

Here are the factors to consider to help you choose the best CBD oil for muscle spasms .

Types of CBD Oil Extracts

The three types of CBD oil extracts are as follows:

  • Full-spectrum CBD oil
  • Broad-spectrum CBD oil
  • CBD isolates

Full-spectrum CBD oil contains all extracts of the cannabis plant , including terpenes , flavonoids, essential oils, and other cannabinoids . Furthermore, the THC concentration is less than 0.3% ( 38 ) .

Broad-spectrum CBD oil is similar to full-spectrum. The only difference is that broad-spectrum CBD is nearly THC-free .

Meanwhile, CBD isolates , typically harvested from Cannabis sativa, are a pure form of cannabidiol ( 39 ) .

A study from Frontiers in Plant Science indicated that the entourage effect in full-spectrum hemp extracts may produce better health benefits than pure CBD (40 ) .

The entourage effect is a premise that when there is an integration of numerous cannabis compounds, their medicinal effects may be enhanced.

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Source of Hemp

For hemp-derived CBD products , it is necessary to identify the source of hemp.

Some CBD products may contain pesticides , fertilizers, heavy metals , or genetically modified organisms (GMOs). These substances are detrimental and may put your health at risk.

Therefore, it is necessary to choose a CBD brand that provides sufficient information on the hemp used . If possible, you should go for organic hemp or non-GMO CBD products manufactured by reputable companies.

Extraction Methods

There are different extraction methods utilized to obtain hemp extract . These techniques include ethanol, natural solvent, steam distillation, and carbon dioxide (CO 2 ) extraction.

One of the most frequently used CBD extraction processes is the CO 2 extraction method. In this technique, compressed CO 2 is used as the extraction solvent ( 41) .

Extraction methods using butane or hexane may leave harmful residues (42) .

CBD and THC Content

Before purchasing any CBD product , you should know the amount of CBD and THC it contains. The dosage is usually expressed in milligrams (mg).

Remember that the CBD potency of a few products may not be specified. Therefore, it is necessary to look for the certificate of analysis (CoA) to verify the accuracy of CBD concentration and potency.

Carrier Oils

After extracting cannabidiol from the hemp plant , the compound is infused into a carrier oil to enhance the product’s bioavailability.

The most frequently utilized carrier oils are coconut oil and hempseed oil. Remember not to confuse hempseed oil with hemp oil. Although most people use them interchangeably, the two terms have significant variations.

Hempseed oil does not contain cannabinoids . However, it is rich in nutrients and fatty acids (43) .

Third-Party Lab Testing

Another vital factor to consider when choosing a CBD product is third-party lab testing. Verify whether the CBD products you are considering underwent a thorough evaluation.

CBD brands must provide lab reports or CoAs of their products on their official website. Ensure to compare the values indicated on the lab results and check whether they match the company’s claims about their CBD products .

The CBD Brand’s Reputation

There is an extensive range of cannabidiol products available on the market, especially online. Hence, verifying whether a particular company is authorized to manufacture and sell CBD merchandise is necessary.

Research the CBD company to determine whether it is a reputable brand that offers only high-quality products. Look into its official website, social media platforms, and find time to read reviews from customers.

Risks and Side Effects of Using CBD for Muscle Spasms

There is no specific study regarding CBD’s risks and side effects when used for muscle spasms.

However, the World Health Organization (WHO) stated that cannabidiol is generally well tolerated with a good safety profile. In humans, the non-psychoactive compound does not show effects indicative of any abuse potential (44) .

Still, there are minor side effects associated with CBD, such as (45) :

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness
  • Fatigue

Aside from these side effects , CBD may also interact with other medications you are taking, like blood thinners (46) .

Blood thinners are types of medicine that prevent the formation of blood clots (47) .

Legality of CBD

The 2018 Farm Bill decriminalized the commercial use of industrial hemp products on a federal level ( 48) .

The bill indicated that Cannabis sativa L. and its derivatives with less than 0.3% THC are legal in the United States.

In 2020, the World Anti-Doping Agency (WADA) removed CBD from the list of prohibited substances. If you are an athlete, this mandate applies whether you are in or out of a competition (49) .

Despite these developments, you should still familiarize yourself with various state laws regarding the use of CBD, especially when traveling.

Different states may impose varied rules and regulations. Therefore, it is recommended that you read state laws to avoid possible legal repercussions.

In South Dakota, for instance, the local government does not permit the possession of any CBD products . CBD oil is illegal in Mount Rushmore State (50) . Hence, owning any CBD merchandise is deemed a violation of state law.

On the other hand, Colorado legalized the adult use of marijuana in November 2012 by passing Amendment 64, a ballot measure to amend the Colorado State Constitution (51) .

Still, even if you hold a valid medical marijuana card, officers in Colorado can arrest you for impaired driving.

According to Colorado state law, if you drive with five nanograms of THC per milliliter of whole blood, you can face litigation for driving under the influence (DUI) (52) .

In addition, when you travel, you should keep cannabis products within Colorado . Remember that you cannot bring cannabis products to Denver International Airport.

Other Treatments for Muscle Spasms

When a muscle spasm strikes, you can take the following steps to alleviate the pain (53) :

  1. Stretch the affected area and massage it with your hands or use a massage roller.
  2. Apply heat or ice. Position the ice pack onto the affected area or apply a heating pad.
  3. Stand up and walk around.
  4. Take prescription medications or over-the-counter painkillers , such as ibuprofen or acetaminophen.
  5. Take vitamin B12 complex daily.

Product Frequently
Asked Questions

How can CBD help with muscle spasms?

Research from the European Journal of Pain indicated that CBD topical application may reduce inflammation and pain without detrimental side effects (54) .

CBD has anti-inflammatory properties (55) . It also has pain-relieving effects (56) . Since CBD may offer pain relief , it may also help with certain conditions, such as muscle spasms .

What evidence or research exists to say that CBD helps with muscle spasms?

T here is no direct evidence that links CBD’s therapeutic effects on muscle spasms . However, results from studies support the use of cannabinoids to treat spasticity and chronic pain (57) .

A systematic review and meta-analysis showed that about 37% of participants who used cannabinoid treatments in a randomized clinical trial experienced a reduction of pain (58) .

Meanwhile, a study investigating the effects of Sativex stated that CBD has a muscle relaxant property that may help people with muscle pain conditions (59) .

Sativex is an oral mucosal spray that has CBD and THC as the main ingredients. The treatment is used for spasticity and multiple sclerosis (60) .

Furthermore, a 2018 study suggested that CBD may benefit people with nerve-related pain (61) . If a nerve-related condition is the cause of your back spasms, CBD may help you manage the pain.

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Is there any evidence that CBD can make muscle spasms worse?

There is no specific study indicating how CBD can make muscle spasms worse.

However, several studies suggest that cannabidiol has the potential to reduce pain and inflammation. Nonetheless, more clinical research is required to confirm that CBD will not worsen inflammatory-related conditions over time (62) .

Will CBD interact with any current medication I may be taking for muscle spasms?

There is no specific study indicating how CBD can interact with other medications for muscle spasms.

Although CBD is well tolerated, it may still interact with other medications you are taking, such as blood thinners (63) . Blood thinners prevent blood clots from forming (64) .

Remember that if you are taking blood thinners, your options for pain relief are limited. Nonsteroidal anti-inflammatory drugs ( NSAIDs) affect how platelets work and interfere with normal blood clotting (65) .

Hence, before mixing CBD and any painkiller with a blood thinner for muscle spasms , be sure to speak with your physician.

Are there other treatments I should consider alongside CBD to help with muscle spasms?

You may use other alternative treatments for muscle spasms , such as heating pads and a daily intake of vitamin B12 complex (66) .

However, always talk with a physician expert in cannabis use before using other treatments alongside CBD for muscle spasms .

Can I fail a drug test if I use CBD for muscle spasms?

Using CBD oil with less than 0.3% of THC may not show up in a drug test. Still, frequent use of cannabidiol may lead to increased levels of THC (67) . High THC levels in the body may generate a positive drug test.

What is the dosage for muscle spasms?

T he Food and Drug Administration ( FDA) has not recognized CBD as a medical treatment (68) . Therefore, there is no standard dosage for CBD.

However, the rule of thumb is to start with a low CBD dosage then gradually increase the amount if you do not observe any adverse side effects .

A study from Current Drug Safety showed that doses ranging from 1mg to as high as 1,500mg of CBD per day are well tolerated by humans (69) .

Still, it is best to get advice from your physician to find the optimal dosage for your condition.

Is CBD oil safe for muscle spasms?

The World Health Organization (WHO) reported that cannabidiol is generally safe (70) . There are multiple quality products available on the market that include CBD as the main ingredient.

However, it is essential that you first consult a medical professional experienced in cannabis use before trying CBD oil for muscle spasms .

Is CBD an effective muscle relaxant?

At the end of a long workday, when our bodies hurt, we often turn to popular prescription medications.

Medications such as Flexeril or Valium offer a quick fix to muscle spasm, pain, soreness, and tension.

Unfortunately, these medications come with a laundry list of troubling side effects and can be highly habit-forming, leading to problems more severe than muscle pain down the road.

Cannabidiol—CBD, a substance derived from the industrial hemp plant—is showing massive promise as an alternative to prescriptions as a safe, effective muscle relaxant.

Understanding how CBD may work as a muscle relaxant first requires some knowledge of the body’s endocannabinoid system.

The human endocannabinoid system

The importance of the body’s endocannabinoid system is increasingly being recognized in the scientific and medical communities; the endocannabinoid system affects virtually every other physiological system in the body, a fact which may explain the far-reaching medicinal benefits associated with CBD and other cannabinoids.

Chemical messengers moderate all sorts of functions in our brains and bodies. For example, neurotransmitters such as serotonin release from a presynaptic cell, travel across the synapse (the space between neurons) and attach to a postsynaptic cell.

Endocannabinoids—cannabinoids made inside our bodies, such as anandamide and 2-AG—work oppositely. They release from the post-synaptic cell, flow across the synapse, and land on the presynaptic cell. This process allows the postsynaptic cell a flow-control mechanism, telling the presynaptic cell when it’s had enough or needs more of a particular chemical messenger.

CBD as a muscle relaxant

When a muscle contracts, it is due to these chemical messengers originating from the central nervous system, going to a muscle, and forcing it to contract. Without a proper supply of endocannabinoids, there is nothing to slow down these excessive chemicals, causing muscles to contract continuously. An insufficient supply of endocannabinoids is a medical condition called Clinical Endocannabinoid Deficiency, or CECD.

CBD directly aids in slowing down this flow of chemical messengers, and it also boosts the body’s supply of endocannabinoids, resulting in a two-fold effect: assisting with muscle relaxation and reducing spasticity.

CBD and chronic stress

Additionally, muscle rigidity, tension, and spasticity can be the result of chronic stress or overwork. CBD shows great promise in helping reduce high anxiety levels, which in and of itself creates a huge health bonus to the body and quality of life in general.

A 2015 study in Neurotherapeutics notes: “Overall, current evidence indicates CBD has considerable potential as a treatment for multiple anxiety disorders, with need for further study of chronic and therapeutic effects in relevant clinical populations.”

If you feel less anxious and stressed after taking CBD, you may be more inclined to hit the gym or a yoga class after work, instead of vegging out in front of the TV or computer.

CBD or THC: Which is better for muscle relaxation?

While CBD alone works well for aiding muscle relaxation, studies in mice, including 2010 research published in Journal of Pharmacy and Pharmacology, have demonstrated that an equal combination of THC and CBD is even more effective. (We aren’t recommending you run out and smoke marijuana, but merely stating what the research shows.) For muscle relaxation, CBD creams and topicals are the most recommended form of consumption.

As with any natural product, always consult your health care provider before embarking on any natural products regimen.

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