Cbd oil for brain lesions in cats

Feline cognitive dysfunction as a model for Alzheimer’s disease in the research of CBD as a potential treatment—a narrative review

With the improvement in modern medicine, the world’s human and feline (Felis catus, the domestic cat) population is aging. As the population grows older, there is an increase of age-related diseases, such as Alzheimer’s disease in humans and feline cognitive dysfunction in felines, which shares many similarities with Alzheimer’s disease. They both result in cognitive decline and lack effective treatments. In light of their pathological similarities, both occur at old age, and as domestic cats share the human environment and risk factors (cats are considered an indicator to the effect of environmental contaminants on humans as they share exposures and diseases), cats have the potential to be a spontaneous model for Alzheimer’s disease. Classic animal models in many cases fail to predict the results in humans, and a natural model can lead to better prediction of results, thus being both time and cost-effective. The feline disease can be researched in trials that could be simultaneously clinical trials for cats and preclinical trials for humans, also referred to as reverse translational medicine. As both maladies lack effective medical intervention, new potential treatments are merited. Cannabidiol (CBD) is a promising agent that may improve the life of these patients, as it was shown to potentially treat several of the pathologies found in both conditions. yet there is a need for further research in order to establish the benefits and safety of CBD to both human and feline patients.

Background

According to global estimates in 2019, there were over 50 million people suffering from dementia, and by 2050 that number is expected to increase to 152 million (Alzheimer’s Disease International 2020). Alzheimer’s disease (AD) is the most common cause of dementia in humans. The disease causes a gradual cognitive decline appearing at early stages as mild short-term memory loss and is easily compensated. However, the more advanced stages affect everyday life and require support in basic everyday functions (Alzheimer’s Association 2019). The owned cat population is also aging thanks to improved nutrition and medical veterinary care. The aging cat population displays behavioral changes which can be attributed to cognitive dysfunction (Karagiannis and Mills 2014). Feline cognitive dysfunction (FCD) is a disorder in cats which causes a decline in the aging cat’s cognitive abilities, without any known underlying medical reason (Karagiannis and Mills 2014; Gunn-Moore et al. 2015). FCD causes behavioral changes, of which the most common are disorientation, change in social interactions with humans or other pets, changes in sleep wake patterns, house soiling, and excessive vocalization, especially at night (Landsberg et al. 2012; Gunn-Moore et al. 2007). Many cats over the age of 11 present some signs of this disorder, while most are symptomatic from 16 and over. Since these behavioral disorders are difficult for owners to live with and compromise the cat’s quality of life, they are often a cause of euthanasia (Karagiannis and Mills 2014). The diagnosis of this syndrome, in living patients, is based solely on exclusion of other medical or behavioral issues, for example, hyperthyroidism, systemic hypertension, diabetes mellitus (DM), deafness, osteoarthritis (or other causes of chronic pain), and brain tumors (Landsberg et al. 2012), and is complicated as these symptoms are frequently attributed to normal aging of the cat (Bellows et al. 2016). Similar changes can be seen in aging humans and dogs (Landsberg et al. 2012).

The available treatments for humans can only treat the disease’s symptoms as there are currently no targeted drugs that stop or reverse disease progression (Salomone et al. 2012). In cats, there are no registered medications to treat FCD and varying success has been observed from off-label options. Additionally, older cats and especially cats suffering from cognitive dysfunction do not tolerate either handling, or medication or hospitalization well (due to the stress involved). Exploring treatments that can be administered in their food would be beneficial.

Several animal models have shown cannabidiol (CBD) has potential to treat and reverse the changes seen in the brain in AD, although further research to support this is necessary (Watt and Karl 2017).

Alzheimer’s disease and feline cognitive dysfunction severely impair the patient’s health and quality of life and impose a significant burden on their caretakers. As the affected population is expected to grow, there is an urgent need to find treatments that can stop and reverse the deterioration of both human patients and the animal population suffering from similar conditions.

Pathological changes in Alzheimer’s disease and in feline cognitive dysfunction

The accumulation of extracellular plaques is a pathognomonic pathological finding in AD. These are misfolded β-amyloid (Aβ) proteins and tau tangles which are the result of hyperphosphorylated tau proteins. Additional findings present in the AD brain are oxidative stress, microglial activation, neuronal loss, and chronic inflammation in the brain which is linked to the neurodegeneration present in AD (Morales et al. 2014; Sarlus and Heneka 2017). Treating the inflammation had beneficial effects in animal models (Lim et al. 2000). In cats, common pathologies found in the brains of patients diagnosed with cognitive dysfunction include decreased cerebral blood flow, free radical damage, and neuronal loss. Additionally, aging domestic cats may spontaneously develop both β-amyloid and tau pathologies similar but not identical to those seen in human AD (Fiock et al. 2020; Chambers et al. 2015). Several studies found β-amyloid aggregates in the aging feline brain (Gunn-Moore et al. 2007; Gołaszewska et al. 2019; Gunn-Moore et al. 2006), although the aggregates present in human and feline patients are different (Gunn-Moore 2011). Other studies found that cats display tau aggregates in their brain with a similar spread pattern as found in human AD patients (Fiock et al. 2020; Gunn-Moore 2011; Poncelet et al. 2019; Youssef et al. 2016) and with shared characteristics (Head et al. 2005). The chronic brain damage leads to a disease similar to the human Alzheimer’s disease (Gunn-Moore et al. 2015; Gunn-Moore 2011). While cats frequently develop spontaneously occurring Tau pathologies, many other animal species, including dogs, rarely express these pathologies (Chambers et al. 2015). Additionally, cats that show signs of behavioral dysfunction tend to also have Aβ plaques (Cummings et al. 1996).

Animal models for Alzheimer’s disease: laboratory animals versus pets with naturally occurring disease

A cross species approach to disease research can advance the understanding of AD and FCD and benefit patients of all species (Devinsky et al. 2018). There is an abundance of published research concerning AD based on laboratory animals, such as transgenic mice (Rosenmann et al. 2008). Although, when the potential treatments are tested in the clinical trial phases, as required by good clinical practice (GCP) guidelines in humans, the results are not as promising and are sometimes hazardous (Götz and Ittner 2008). Laboratory animal models, such as transgenic mice, frequently fail to predict the outcome of the tested potential treatments in humans (Polson and Fuji 2012). Many drugs that seemed promising in animal models did not succeed in clinical trials (Watt and Karl 2017). In fact, it has been concluded that the available animal models do not reflect the human AD fully or accurately (Birch et al. 2014). Examples in AD research include anti-inflammatory drugs that have beneficial effects in animal models and not in human clinical trials (Grammas 2011). Additionally, anti-Aβ vaccination that was found to prevent the accumulation of amyloid deposits in transgenic mice caused severe neurological complications in some of the human patients who received it (Foster et al. 2009).

There are many possible reasons for the failure to translate results from animal models to humans. The animal experiments were carried out with laboratory animals, mostly transgenic that may manifest other deficits. Relating to limited construct, content, ecological, and face validity, animal models are held in a closed regulated laboratory environment and are not exposed to similar environmental contaminants as human patients, which is of high significance in a disease that is also influenced by environmental factors (Cannon and Greenamyre 2011). Therefore, laboratory animal models cannot accurately model natural occurring diseases in a natural home environment. None of the available animal models can represent AD completely since none of them is able to replicate all the features of the human disease; moreover, very few models have both amyloid plaques and tau tangles (Drummond and Wisniewski 2017). Transgenic animal models do not express all the factors present in the human disease, including pathological changes and disease progression; they also do not reflect the etiology of the human disease which is multifactorial and includes genetic and environmental risk factors (Franco and Cedazo-Minguez 2014). Transgenic animal models usually model only a single pathological feature and lack factors that mimic the environmental factors together with the cognitive deficits and with the pathological features. The ideal model should reflect the entire etiology as well as the disease progression (Franco and Cedazo-Minguez 2014).

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Moreover, transgenic animal models usually include genetically modified young animals, thereby ignoring an imperative factor in AD which is the aging factor. Domestic cats with naturally occurring disease are also aging as the symptoms are present in cats older than 11 years old and more commonly over 16. Additionally, the transgenic models for AD are based on the familial forms of AD which account only for a small percentage of the AD patients (Epis et al. 2010).

A better model for human disease can be found in owned pets with naturally occurring disease which share the human environment (Ritter et al. 2020). Pets are considered sentinels and bioindicators for environmental contaminants effects on humans due to their shared habitat, simultaneous exposure, and similar disease spectrum (Pastorinho 2020; Beck et al. in press). According to the One Health Initiative, there is a strong link between the health of humans, domestic animals, and the environment. Humans and domestic animals share the same environment (including environmental contaminant), common stressors, and many genetic traits (Christopher 2015). One Health promotes human and animal health through integrative study across all animal species (Gibbs 2014). Since cats suffering from FCD are exposed to the same environment as their owners, the disease mechanism is naturally occurring and at an old age, they make a good model. These studies can prove beneficial to human and veterinary patients (Schneider et al. 2018). The brain lesions have common pathological characteristics in humans and cats, and it has been suggested that cats are a natural model of AD; they demonstrate lesions with morphological and biochemical spontaneous changes that are comparable to the human AD lesions and they do so in a shorter lifespan (Head et al. 2005).

It is worth mentioning that dogs are also potentially natural models for AD in humans as many old dogs also suffer from similar cognitive dysfunction (Prpar Mihevc and Majdič 2019).

Clinical feline trials can be preclinical trials for humans, and medication can be simultaneously developed in a time and cost-effective process. These are known today as reverse translational medicine (Schneider et al. 2018). Additionally, they have the potential to promote animal welfare by avoiding unnecessary use of laboratory animals. The feline disease shares many similarities with AD and although the diseases are not identical we suggest that the similarities AD and FCD share warrant exploring the feline disease as a model to the human disease.

Cats and dogs share pathological changes with the human AD and share the human environment which makes them both good candidate models for naturally occurring AD (Takeuchi et al. 2008). While dogs share many similarities with the human AD, cats are one of the only species which displays naturally occurring tau pathologies (Chambers et al. 2015). It was shown that aging cats share three important similarities with human AD; they have spontaneous development of Aβ dispositions, and they have taupathies and neuronal loss which shares distribution and characteristics with AD (Klug et al. 2020). Moreover, it has been shown that there is a correlation between the neuronal loss and cognitive dysfunction in aging cats (Takeuchi et al. 2008). These facts make cats, at the very least a complementary model to dogs in researching naturally occurring AD.

CBD as potential treatment for Alzheimer’s disease

Among the various functions of cannabidiol are anti-inflammatory properties, demonstrated in vitro and in vivo (in rats) (Cassano et al. 2020; Esposito et al. 2011) and antioxidant properties (Esposito et al. 2011; Pellati et al. 2018) in vitro (Hartsel et al. 2019; Kim et al. 2019). Additionally, CBD was found to inhibit the hyperphosphorylation of tau proteins in vitro (Esposito et al. 2006), which, as mentioned, is present in AD human patients and in some FCD patients. CBD has also been shown to increase the cerebral blood flow in vivo (in mouse models after stroke) (Sultan et al. 2017), attenuate the neurotoxicity of the β-amyloid protein accumulation in vitro and in vivo (in mice), modulate microglial cell function (Martín-Moreno et al. 2011), and reverse cognitive deficits in transgenic animal models (in mice) (Cheng et al. 2014). Thus, CBD has the potential to counter many of the pathological processes in AD (Vallée et al. 2017). There is a need for more research regarding the benefits, risks, and doses for CBD treatment in human patients and especially in elderly human patients (Beedham et al. 2020). The safety of the treatment needs to be evaluated for chronic use (Iffland and Grotenhermen 2017), and potential drug interactions should be evaluated as many elderly patients need to be treated for concurrent conditions (Alsherbiny and Li 2018). Additionally, there is a need to research the usage of CBD to treat FCD patients. Combining the research could benefit feline and human patients and save resources such as time and funds. Clinical evidence in treating dementia or AD with CBD is scarce, we conducted an electronic search in “PubMed” and “Google Scholar” for published articles, in English, published in the years 2005 to September 2020, using the key words “Dementia + Cannabidiol + clinical trials”, “Alzheimer’s + Cannabidiol + clinical trials”, “Dementia + Cannabidiol”, and “Alzheimer’s + Cannabidiol”, and their references and citations. We did not find articles regarding clinical trials in treatment of AD or dementia with CBD. Additionally, a few recent comprehensive reviews that addressed the treatment of AD and dementia with cannabinoids did not review clinical trials with treatment of dementia or AD with CBD (Beedham et al. 2020; Inglet et al. 2020; Cooray et al. 2020). A published case communication demonstrated treatment of an 81-year-old man that suffered from dementia after several cardiovascular events and presented with drowsiness, difficulty keeping his eyes open, inability to maintain eye contact for more than a few seconds, inability to speak, difficulties to communicate, and severe spasticity. He was treated with CBD, starting with 3 daily drops of CBD oil and after approximately 7 days the dose was increased to 4 daily drops of CBD oil. A few days after commencing treatment, his alertness and responsiveness improved and he was able to say a few words. A month after beginning the treatment, he remained more alert and responsive, continued to say a few words, and regained his ability to make eye contact for more than a few seconds, and his spasticity decreased. No side effects were reported (Hermush and Ore 2019).

CBD and feline patients

There is a shortage of literature regarding the usage of CBD in domestic cats and the pharmacokinetics and safety must be established. A comprehensive review of the existing literature on veterinary cannabinoid medicine does not mention feline research in the field (Hartsel et al. 2019). One research tested the pharmacokinetics and safety of a single daily dose of CBD in a small group of cats for 84 days and found that it was absorbed after oral administration and that the safety was satisfactory, although monitoring of liver enzymes is necessary (Deabold et al. 2019). Research with larger numbers of cats is necessary to establish the safety and effectiveness of the treatment. Additionally, a double blind study treating domestic feline cognitive dysfunction patients in significant numbers is necessary to determine the usefulness of this treatment for feline patients and its potential use for human patients.

Conclusions

Classic animal models fail to predict the outcome of new treatments more than they succeed. This causes inefficient use of resources and compromises animal welfare without promoting human or animal health. We suggest, in accord with the One Health Initiative, that a better model for human disease can be found in domestic pets, with naturally occurring diseases who share the human environment so the disease mechanisms and features have a higher chance of simulating the human equivalent. Moreover, we suggest that these trials should be conducted as clinical veterinary trials to develop treatment for the parallel conditions in domestic pets, thus enhancing animal welfare, promoting better veterinary care, and saving resources by simultaneously developing treatments for humans and pets. We find feline cognitive dysfunction a promising model for human Alzheimer’s disease. Therefore, we suggest that conducting a clinical trial in aging domestic cats, for researching the benefits of CBD for both conditions, can promote the treatment of these two difficult conditions in humans and pets.

25 Best CBD Oils for Cats with Cancer

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As CBD becomes more popular, pet owners are starting to wonder if it could help their cats with cancer. To be clear: CBD won’t cure or minimize cancer, but it may help ease certain symptoms and help your cat to feel more comfortable. Here, we take a look at 25 of the best CBD oils for cats with cancer and explore how they may be able to help.

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25 Best CBD oils for Cats with Cancer

3. Nuleaf Naturals

4. cbdMD Pet CBD Oil Tincture

5. 4 Corners Cannabis Pet Tincture

6. Canna-Pet Advanced MaxCBD

7. Mary’s Nutritional Tails Pet CBD Tincture

8. MedTerra Hemp CBD Soft Chews

10. Pet Hemp Company

11. Honest Paws CBD Oil

12. Joy Organics

14. Penelope’s Bloom

23. Charlotte’s Web

24. Cornbread Hemp

What is CBD oil?

CBD is the abbreviation for cannabidiol, a natural compound found in cannabis plants. It’s one of many compounds known as cannabinoids, but it’s non-psychoactive – meaning it won’t get your cat high.

CBD works by triggering cannabinoid receptors found throughout the body and brain. These receptors are what allow cannabinoids to regulate a range of body systems including appetite, mood, pain sensation, and inflammation.

CBD comes in many forms including oil, capsules, sprays, and e-liquids for vaping. Today we’re focused on CBD oils for cats with cancer.

CBD oil dosage for cats

The first thing you need to do is talk to your vet before adding CBD to your cat’s treatment regimen. Then, decide what concentration of CBD you want in your product, and how much you will give your cat. For example, this list includes different dosages from 2 mg up to 100 mg per serving.

CBD oil dosage for cats is affected by a number of factors including weight, age, and current medical conditions such as cancer.

It’s always best to start with the lowest dosage possible and work your way up until you find the most effective dose. Dosages can also be adjusted gradually if needed.

Finding the right CBD level can be tricky, especially since different concentrations are available. A general rule of thumb is to consider the total milligrams (mg) of CBD for one serving and divide this number by how many times you will give your cat a dose each day. This should give you an idea of what concentration you need to aim for.

How often you give your cat a dose also depends on the product. Try to reach each of the best CBD oils for cats with cancer labels before choosing one for your cat.

How we selected the best CBD oils for cats:

Below you’ll learn more about the factors we considered before including a brand on our list of the 25 best CBD oils for cats with cancer:

Quality

One of the most important factors when choosing CBD oil for your cat is quality. We only included brands with the highest-quality ingredients and manufacturing processes.

Price

Our list includes 25 different CBD oils from 2 mg up to 100 mg per serving, making it easy for you to find something that will work within your budget.

Customer reviews

When available, we included CBD oil reviews from previous customers. We also considered feedback from verified purchases of each product on Amazon where available.

Brand reputation

We only included brands with a strong reputation for quality and value for money. All of these companies have been vetted by us before being listed on this list.

All 25 best CBD oils for Cats with Cancer

Each of the products here has been selected because it offers a safe, natural way to help your cat with cancer. We’ve included products from reputable brands that are experts in the field of pet medicine.

1. Penguin CBD

Image courtesy Penguin CBD

Looking for a way to help your ailing or aging cat feel young again? Penguin CBD oil is salmon flavored and made with the finest Oregon grown hemp. This supplement can help rejuvenate your furry friend. Their broad-spectrum extract contains 0% THC, ensuring that your pet stays healthy and happy.

CBD oil is a great way to help your cat live a healthier life. Penguin CBD’s all-natural, broad-spectrum hemp oil is available in 150 mg and Salmon flavor, which has been specially formulated for cats. Help your furry friend live a happier and healthier life with this CBD oil supplement.

2. Verma Farms

Image courtesy Verma Farms

Looking for an easy and natural way to keep your cat healthy and happy? Look no further than Verma Farms CBD! Their award-winning CBD is perfect for cats of all ages and comes in a delicious chicken flavor that your kitty is sure to love.

3. Nuleaf Naturals

Image courtesy Nuleaf Naturals

Nuleaf Naturals has you covered with their CBD oil! This whole-plant extract contains a full spectrum of naturally occurring synergistic cannabinoids and terpenes, making it perfect for pets of all kinds. Simply add a drop or two to your pet’s food, favorite treat, or give it to them directly – they’ll love the taste!

4. cbdMD Pet CBD Oil Tincture

Image courtesy CBDmd

CBDmd Pets offers your feline friend the benefits of premium CBD oil. Their tinctures are made with hemp-derived extracts that may help support better health by improving calmness and relaxation, as well as enhancing your kitty’s well-being in various ways.

5. 4 Corners Cannabis Pet Tincture

Image courtesy 4 Corners

4 Corners Cannabis has a line of CBD pet products that are made with 100% hemp seed oil, which is gentler on animals’ stomachs than the MCT base used in their oral tinctures. Hemp oil contains omega-3 and -6 fatty acids, which are known for their many health benefits to humans!

6. Canna-Pet Advanced MaxCBD

Image courtesy Canna-pet

Are you having trouble getting your cat to eat? Introducing Canna-Pet CBD capsules, the easy way to get your pet taking their CBD oil. Just open up the capsule and mix it into their food–it’s that simple! Hemp Canna-Pet Advanced Small capsules contain a broad spectrum of concentrated cannabinoids, terpenes, and flavonoids to help stimulate your cat’s appetite and relieve inflammation and pain.

7. Mary’s Pet CBD Tincture

Image courtesy Mary’s Tails

Looking for a natural and holistic way to improve your pet’s wellness? Mary’s Tails CBD is the answer. Their Hemp Extract Tincture in bacon flavor delivers 300 mg of CBD, making it a potent and consistent addition to your pet’s routine.

8. MedTerra

Image courtesy MedTerra

Keep your furry friend happy and healthy with Medterra CBD products. These all-natural, organic products are veterinarian recommended and clinically tested to be beneficial for cats and dogs. With three types of products to choose from, you’re sure to find the perfect one for your pet.

9. HolistaPet

Image courtesy HolistaPet

Holistapet CBD products are perfect for your furry friends. With no THC, these products are safe and perfect for keeping your pet healthy and happy. Holistapet offers a variety of CBD products to choose from, including oils, chews, and treats. Your pet will love the delicious salmon flavor!

10. Pet Hemp Company

Image courtesy Pet Hemp Company

Pet Hemp Company’s CBD oil is ideal for pets of all shapes and sizes, and it’s formulated with other cannabinoids to provide a broad spectrum of benefits. Plus, their superfoods are packed with nutrients that support your pet’s health and well-being.

Simply administer the oil directly into their mouth or mix it in with their food or water – there’s no THC so you don’t have to worry about them getting high. And because they make their products in the USA, you can trust that they’re of the highest quality. Give your furry friend the best life has to offer with Pet Hemp Company.

11. Honest Paws CBD Oil

Image courtesy Honest Paws

Honest Paws is revolutionizing the pet industry with CBD products that are 100% natural and effective. CBD has been proven to help improve the health and wellbeing of cats and dogs, and Honest Paws makes it easy to find the perfect product for your pet. With a wide range of options, you can choose based on what you’re trying to target, such as wellness, skin care, anxiety relief, pain relief, immunity, or mobility.

12. Joy Organics

Image courtesy Joy Organics

For a USDA Certified Organic CBD oil tincture to give your furry friend, try Joy Organics! Their premium CBD Oil Tincture for Pets is made with organic olive oil and organic broad spectrum hemp extract, ensuring that your pet gets all the benefits of CBD without any THC.

13. Petly CBD

Image courtesy Petly CBD

Petly CBD specializes in making delicious and nutritious CBD treats and toppers for cats and dogs. Whether you’re looking to help manage a specific condition or just want to give your pet some extra nutrition, Petly CBD has you covered.

14. Penelope’s Bloom

Image courtesy Penelope’s Bloom

For a CBD product that will help improve your pet’s joint mobility, relieve pain, and support healthy skin, try Penelope’s Bloom. Their products are organic and non-GMO, making them ideal for any pet. With concentration levels that are optimal for pets, your furry friend will be able to experience the benefits of CBD quickly and easily.

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15. Pure Kana

Imagme courtesy Pure Kana

Pure Kana’s CBD products are some of the best in the industry, offering high-quality supplements for both humans and animals. With multiple flavor options to choose from, you can find the perfect CBD supplement for your pet. Pure Kana also has a wide variety of products to choose from, making them one of the most popular CBD brands online.

16. CBDfx

Image courte3sy CBDfx

Offering products specifically designed for dogs and cats, CBDfx has something for every pet owner. With dosage options ranging from 250 mg to 2,000 mg, and products including CBD oil, treats, and bundles, this brand is a top pick among pet owners.

17. Green Roads

Image courtesy Green Roads

CBD oil has become a popular supplement for people of all ages and walks of life, and now your furry friend can enjoy the benefits, too! Green Roads offers a blend of MCT oil and hemp-derived cannabinoid extracts to promote better digestion and absorption of CBD. The result is a product that supports your pet’s health and well-being in a tasteful and convenient way.

18. FabCBD

Image courtesy FabCBD

To help your furry friend calm down, try FabCBD CBD treats! These treats are soy, wheat, dairy, and allergen-free, and are made with CBD oil that’s been extracted without THC. So you can rest assured knowing that your furry friend is getting all the benefits of cannabinoids and terpenes without any psychoactive effects.

19. JustCBD

Image courtesy Just CBD

Offering everything from bacon-flavored CBD oil to beef-flavored CBD oil, this company has something for everyone. And with unique products like cat and dog treats, you can be sure your pet is getting the best possible care.

20. Hemp Bombs

Image courtesy Hemp Bombs

Hemp Bombs’ high-class products are designed to improve your furry friend’s quality of life. Choose from 250 mg or 1000 mg bottles, made in the USA and clinically tested. These oils are perfect for giving your pet relief from anxiety, pain, and other common issues.

21. Royal CBD

Image courtesy Royal CBD

Royal Paws’ high-quality hemp extracts are perfect for keeping your furry friend healthy and happy. Royal CBD for pets’ bacon-flavored CBD oil is easy to administer, and your dog will love the delicious taste.

22. EVN CBD

Image courtesy EVN

EVN CBD is an all-natural solution to staying calm and collected during your busiest days. Hemp-derived cannabidiol (CBD) helps reduce stress and anxiety, while promoting feelings of relaxation and well-being. Simply take a few drops whenever you need an edge in life, or add it to your favorite food or drink for easy access.

23. Charlotte’s Web

Charlotte’s Web is a hemp extract that provides relief from various conditions. It comes in an unflavored and chicken-flavored option, and the product features a graduated dropper for easy use.

24. Cornbread Hemp

Image courtesy Cornbread

This premium vegan pet food is made with only the finest ingredients, including our Flower-Only™ hemp extract. The balanced THC and CBD content helps keep your pet calm and comfortable, while the delicious Corndog flavor keeps them coming back for more. So give your pet the best of both worlds with Cornbread Hemp.

25. Everest

Image courtesy Everest

Everest’s line of CBD oils is vegan, non-GMO, and USA-made with only the highest quality hemp, and are available in a delicious blueberry flavor that even cats will love.

What are the benefits of CBD oils for cats with cancer?

There are many reasons why cat owners give their feline friends CBD oil, below are just a few of the reasons people have shared online:

Better Mood

Cats are great companions, but they can be a bit moody, especially when they’re not feeling well. It’s hard not understanding why your cat is acting out in such an emotional way when you just want them happy again.

Lowering Anxiety

CBD has been shown to decrease anxiety and help your cat relax. This is great for cats who experience illness or anxiety when they’re in a new place, during loud noises or when around other animals.

Lowering Pain

Cats and CBD oil can be the perfect combination to reduce pain and discomfort caused by age, arthritis, injuries, and more.

Boost Immune System

Since CBD oil can reduce inflammation it can also help your cat fight off illnesses and disease.

Treating Cancer

While CBD has not been known to cure cancer, it has helped improve the quality of life for many cats living with this disease. And with no serious side effects, using CBD oils is a safe choice when you consider how much time together your cat and you have left.

What are the side effects of CBD oils for cats with cancer?

Since there are no serious side effects associated with using CBD oil, there are none to worry about when giving it to your cat, either.

Cats have a higher sensitivity to smells than people, so you will want to examine the oil before giving it to your cat. If it smells too strong, dilute it by adding water or placing the drops in some food.

How do I give my cat CBD oils?

Before starting any new treatment for your pet, make sure to talk with your veterinarian about dosage instructions.

Every cat is different and every type of cancer will affect your pet differently. As a general rule, cats should take between 0.25 mg to 1 ml a day. This can be easily adjusted as needed during treatment either by adding more drops or lowering the dose depending on how your cat reacts.

As with any health supplement, make sure to read the product label carefully and follow the instructions on how to use it.

Are there other ways to give my cat CBD oil besides putting it in their food?

Yes! If you’re wary about putting the oil in your cat’s food, you can also just use a toothpick to apply it directly to their mouth. Or if your cat would rather not eat it at all, you can always give them CBD through an easy-to-use CBD oil spray or cream.

Can you give human CBD oil to cats with cancer?

The content of CBD in your pet’s food or treats should not exceed 0.3%, as this could make them unsafe for cats. However, the difference between human-oriented oils and those made specifically to satisfy furry friends’ needs can be dramatic.

You could find that just 1 mg will provide an ample amount depending on your cat’s size. So yes, you can give human CBD oil to cats with cancer, as long as the THC content is under 0.3% THC.

Are CBD oils safe for cats?

CBD is considered safe and non-toxic even in high doses, but you will want to stick with organic hemp oil that meets the criteria mentioned above. When shopping for your cat’s CBD oil be sure it comes from a reputable company.

Make sure any product you’re considering has been tested by a third-party lab to ensure the quality and potency of the CBD oil you’ll be giving your cat.

Where can I buy CBD oils for cats with cancer?

There are numerous high-quality brands available online, so it is easy to find a CBD oil that meets all of your needs and preferences. Before deciding which product to give your cat, do your research to ensure it has been tested.

The best advice for buying CBD oils for cats with cancer is the same as when shopping for any health supplement – stick with companies you know and trust, read ingredient labels carefully, ask questions, and do your research before choosing a product.

When looking at the big picture, using CBD oils for cats with cancer is a safe, effective treatment that will not interfere with other medications. Most importantly, it has no serious side effects and you’ll find your cat’s quality of life greatly improved in the process.

Final Thoughts

CBD oils for cats with cancer is a great alternative to a number of pharmaceutical drugs that carry harmful side effects. If you’re not sure about giving your cat CBD, do some research online and speak with the vet before trying it. It may be just what your cat needs to improve their quality of life.

Again, it is important for owners to consult with veterinarians prior to administering CBD oil to their pets.