Cbd oil for chronic hives

Study to Evaluate the Safety, Tolerability and Efficacy of Cannabidiol (CBD) as a Steroid-sparing Therapy in Chronic Spontaneous Urticaria (CSU) Patients

Each patient will commence the study with a one month run-in period in which he/she will be administered individual patient Standard of Care :anti-histamines and steroids as needed plus placebo (olive oil).

After the run-in period, doses of CBD will be incresed during the first six weeks of the study.

At the conclusion of the six weeks CBD dose escalation segment of the study, if the 300 mg CBD dose level is deemed safe for two weeks with standard of care doses of anti-histamines, patients will continue receiving 300 mg CBD with Anti-histamines as needed for an additional follow-up period of three month.

Each patient will serve as his/her own control.

Condition or disease Intervention/treatment Phase
Chronic Spontaneous Urticaria Drug: CBD Phase 2

Each patient will commence the study with a one month run-in period in which he/she will be administered individual patient Standard of Care :anti-histamines and steroids as needed plus placebo (olive oil).

At the end of the one month run-in period, all trial subjects will continue on individual Standard of Care plus increasing doses of CBD during the first six weeks of the study. Dosage of CBD will start at 25 mg twice daily and will be increased once every 14 days, if no side effects are observed, to 50 mg twice a day, 100 mg twice a day and finally to 150 mg twice a day CBD respectively. Treatment will be given with food.

At the conclusion of the six weeks CBD dose escalation segment of the study, if the 300 mg CBD dose level is deemed safe for two weeks with standard of care doses of anti-histamines, patients will continue receiving 300 mg CBD with Anti-histamines as needed for an additional follow-up period of three months. In the case of flare, the patient will be treated with higher dose of Anti-histamines and Steroides if needed in addition to CBD. Once the flare has been brought under control, then another attempt will be made to discontinue the steroids and continue treating with CBD + Anti-histamines only. Each patient will serve as his/her own control.

Laboratory studies will be carried out at the beginning of the study (baseline), and then on a monthly basis until the end of the study.

4 skin problems that you can solve with CBD (and select herbs)

CBD oil is a natural active ingredient derived from the Cannabis sativa industrial cannabis species. CBD cannabinoid has so many positive effects on the human body, we often joke that every person has at least one ailment CBD oil could help with. CBD is used to relieve insomnia and chronic pain, and to help relieve autoimmune diseases, anxiety and depression. It is also popular as a natural remedy against insomnia and as an additional boost for the immune system. Lately, the use of CBD oil for the skin has also been gaining a lot of attention. Because the skin has its own endocannabinoid system to which the CBD cannabinoid binds, it is effective in a wide range of skin problems. What skin problems does CBD work on best?

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CBD and psoriasis

Psoriasis is a chronic autoimmune disease where skin cells grow and divide at an accelerated rate. Eczema start appearing on the skin as a result of this division and they are usually red with a silver outline but can also be pink or brown in colour. Psoriasis is a disease that doesn’t have a cure yet, but various therapies do exist to mitigate its symptoms. A lot can be done to alleviate the symptoms by adjusting your lifestyle, maintaining a balanced diet and with moderate exposure to the sun. CBD cannabinoid is also becoming an increasingly popular natural remedy for psoriasis outbreaks and several studies have shown the effect it has on decelerating skin cell division. CBD cannabinoid also has anti-inflammatory properties which additionally soothe psoriasis conditions. You can read more about CBD cannabinoid use in psoriasis treatments in one of our previous posts: Does CBD oil help with psoriasis?

Something that actually helps .
“At last, I’ve found something that actually helps .
Great texture, lovely smell, absorbs easily and really helps the irritated and flaky atopic skin on my arms hands and face.
Can not recommend it enough.” – Cherly

Acne and skin impurities – CBD’s double effect

Acne and skin impurities are not exclusive to teenagers, they often occur in adulthood as well. Most commonly the causes of adult acne are hormonal imbalances, stress, an unhealthy diet and improper skin care. Their formation is caused by an increased secretion of sebum (tallow) and the Propionibacterium acnes bacteria. Sebum normally plays an important role in skin protection, but when the skin produces too much of it, it can also cause unwanted acne. Our fight against acne can take place on multiple levels – with a healthy diet, regular cleansing of dead skin cells, avoiding stress and regular physical activity. Of course, proper skin care that balances the skin and brings it to a healthy and radiant state is crucial. And CBD cannabinoid is undoubtedly an active ingredient which, when it comes to acne skin care, is very promising. Why is CBD a great ally in the fight against acne?

1. CBD reduces the formation of sebum in sebaceous tissues
Clinical studies have shown that the CBD molecule reduces the formation of sebum in the sebaceous glands, which is highly desired in acne-prone skin care, as the formation of sebum is the most common culprit of acne.

2. CBD has antibacterial and anti-inflammatory properties
CBD carries out complex anti-inflammatory and antibacterial actions demonstrated also in many other experimental studies on diabetes, rheumatoid arthritis, etc. Red acne (not blackheads) are the result of inflammatory skin changes that CBD cannabinoid can successfully calm down.

Best cream against acne!
This is the first time that I find a cream that can balance my combination skin, 35 and finally no more spots!!” – Luisa T.

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New favorite product in my skin care routine!
I’ve used several other brands and skin care lines with hemp and CBD based products and found the Balancing Face Cream to be the most helpful in moisturizing and preventing acne. This moisturizer is light, non greasy and balances my skin.” – Sarah V.

A healthy, clean and refreshed complexion is something that we all long for! This set includes: Balancing Face Cream 50ml, which restores balance and normality, and moisturizes combination an oily skin. Purifying Face Cleanser 100 ml, which gently and effectively cleanses skin

CBD cannabinoid and atopic dermatitis

Dermatitis is an inflammatory skin disease that most commonly occurs in children. About 10% of children under the age of 6 are affected. Dermatitis is more common in cold months and is characterized by red, itchy rashes. If you visit your doctor with a case of dermatitis, they will almost always prescribe treatment with corticosteroid creams. Such creams are effective in relieving the symptoms, but unfortunately, they also have a lot of negative side effects on the skin and body. Often, when the treatment with corticosteroids is completed, the original problem returns.
CBD cannabinoid has an anti-inflammatory effect on the skin and body. Atopic dermatitis is an inflammatory disease, so CBD has a positive effect on it.

CBD is all the more effective because our skin has its own endocannabinoid system onto which CBD can bind itself directly when it’s in the form of an ointment. This way it has a quick and targeted effect on the problem, calming the skin and restoring its balance. CBD also soothes itchiness and redness, two of the more prominent problems of atopic dermatitis. Read how Therapeutic CBD Skin Balm was the answer for a desperate mommy looking for the solution to her son’s skin problem in this interview. Interview: Finally we have got rid of topical steroid creams.

Concentrated CBD treatment balm tackles the toughest symptoms of atopic skin, alleviates skin reactions and soothes eczema flare-ups. Reach for it when skin needs fast-acting help for inflamed, reddened and itchy conditions. It provides intense relief and unique nourishing care. Ingredients: High concentration of CBD extract is a powerful anti-inflammatory and skin-soothing properties. Hemp seed oil, rich in essential fatty acids omega 3 & 6, Vitamin E and minerals – the building blocks of healthy skin. Calendula, shea and mango butter soothe and nurture.

CBD oil is also effective with seborrheic dermatitis

Seborrheic dermatitis is a fairly common chronic inflammatory skin disease that most often affects the face and scalp area. It appears in the form of red, scaly skin on the scalp and around the hairline, often manifesting itself behind the ears and in the skin folds (elbows, knees, under the breasts). The main cause is the increased production of sebum in the sebaceous glands. CBD is a great ally in the care of seborrheic dermatitis. Why?

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1. CBD slows the secretion of sebum

The most common cause of seborrheic dermatitis is the excessive secretion of sebum from the sebaceous glands. Because CBD has been proven to reduce sebum secretion, it is effective in the fight against seborrheic dermatitis. Because of this, it is also effective in treating acne and impure skin.

2. CBD slows down cell proliferation on the skin

The rapid reproduction of skin cells caused by the Malassezia fungus is another important factor in the onset of seborrheic dermatitis. Clinical studies have proven that the CBD molecule reduces sebum secretion from the sebaceous glands and inhibits the rapid reproduction of sebocytes, the cells that make up sebaceous glands and affect the onset of seborrheic dermatitis.
Why is CBD cannabinoid so effective when dealing with skin conditions?

CBD cannabinoid binds to the endocannabinoid system in our body. It contains phytocannabinoids, which are cannabinoid molecules very similar to the endocannabinoids our body contains naturally. Endocannabinoids coordinate the functions of our whole organism, helping the body when it is sick or under stress. It could be said that the endocannabinoid system is the conductor of our body, ensuring that our bodies stay in tune and work harmoniously. CBD cannabinoid is so effective in fighting skin problems because our skin has its own endocannabinoid system. This system ensures that our skin is healthy and balanced. Ointments containing CBD cannabinoid bind directly to the endocannabinoid system in the skin, helping the skin find its balance quickly and effectively.

Our Choice for Most Effective Psoriasis treatment:

Award Winning

Therapeutic CBD Skin Balm

Relieves, protects and revitalises acutely irritated skin.

Keeps psoriasis spots under control. . I’m fighting with my psoriasis for about 40 years now. It was CBD oil and skin balm that helped me keep it under control. Many thanks. ” – Robert W.

It really helps the irritated and flaky atopic skin on my arms, hands and face.” – Cheryl

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