23 Best CBD Creams for Neuropathy in Feet
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There are an estimated 2.5 million people in the USA who suffer from neuropathy, a condition where nerves all over the body become inflamed and damaged, causing pain and numbness. This can happen due to diabetes or other medical conditions or for no reason at all (idiopathic). Today we’re going to discuss the best CBD creams for neuropathy in feet.
9. CBDfx Muscle and Joint Cream
10. Lord Jones CBD Body Oil
11. CBD FX Foot Care Set
12. CBDMedic Aches and Pain Relief
13. Vertly Lotion
14. Harmonious CBD
15. CBDistillery Oils
16. Pure Hemp Isolate Cream
17. BioTech CBD Oil Roll On
18. NuLeaf Naturals CBD Salve
19. CBD.Co CBD Foot Care Bundle
20. Aspen Green Muscle Relief Cream
21. Level Select 2 CBD Sports Cream
22. Medterra Pain Relief Cream
What is CBD oil cream?
CBD oil cream is a natural product made from CBD oil. It’s often used to treat skin conditions like eczema and arthritis, but it can also be used for neuropathic pain relief. The non-psychoactive compound of the cannabis plant, CBD oil offers many benefits for people with various symptoms and serious medical conditions.
How does CBD oil cream work?
CBD works by reducing inflammation and blocking the pain signals that are sent to your brain. The endocannabinoid system (ECS) is a big part of this process as it helps cells stay in homeostasis. Every time you use cannabis, whether it’s from smoking or from a hemp product like CBD oil, your ECS reminds cells to function properly. CBD is said to help regulate over 5 major systems:
· The digestive system
· The nervous system
· The immune system
The endocannabinoid system controls many of your body’s major functions, and it is very important that we keep this system working at its best. This will help to regulate sleep, appetite, immune function as well as pain and sensory perception such as smell and sight.
What symptoms does CBD oil cream treat?
CBD is effective at treating symptoms both big and small. It’s been proven to be beneficial for people struggling with arthritis, chronic pain, and more serious conditions like cancer and multiple sclerosis. It can be used for a variety of skin conditions as well. In the case of neuropathy in feet, CBD cream delivers targeted relief to inflamed nerve endings and calms itchy skin.
How do I know if my neuropathy in feet will respond to CBD oil cream?
Many people find that CBD helps relieve pain from all types of neuropathy, but some conditions respond better than others. The first step is to talk to your doctor about CBD oil cream. If they feel that you could benefit from it, they will recommend a product and help you determine if your specific condition can be treated with CBD.
How do I use CBD cream on my feet?
CBD cream on the feet should be applied two to three times a day. Apply a generous amount of cream and massage into the affected area. Most CBD companies recommend that you start with a pea sized amount and work your way up from there, depending on the severity of your condition.
How does CBD oil cream benefit people with neuropathy in feet?
People who suffer from neuropathy in feet often experience severe pain and discomfort in their feet. They may feel like they’re walking on pins and needles or that it feels like they’re being stung by bees. CBD oil cream works to block the pain signals sent from these damaged nerves so that you feel less discomfort. Many people who have experienced relief from CBD oil cream say it’s a lifesaver for them and have even tried other medications, which didn’t work as well, before trying this natural alternative.
What is CBD cream made of?
CBD oil cream is made from CBD oil, coconut oil, shea butter, cocoa butter, hemp seed oil and essential oils. It’s important to note that not every cannabis company uses the same blend for their CBD creams. Some offer a more potent product, while others offer a lighter formula. Always make sure to check the milligrams of CBD in each serving before using CBD oil cream.
What are the benefits of CBD creams?
CBD lotions give you all the health advantages of cannabis-based products in general, and CBD in particular, without any psychoactive effects. This makes it a great option for people who want the benefits of cannabis but don’t like the high or side effects (which can include euphoria and/or dizziness) associated with marijuana products.
Are there any side effects of CBD oil cream?
As with any new medication, it’s important to check with your doctor first before using CBD oil cream or any other cannabis product. It’s also vital to know that not everyone responds the same way to CBD products so it is best to use trial and error to determine if this treatment works for you. There are some people who may experience an upset stomach, dry mouth or drowsiness when using CBD products.
Is hemp oil the same as CBD oil?
CBD oil comes from the plant, hemp. Hemp is part of the same family as marijuana but it’s not the same. CBD oil will not get you high and there are no psychoactive properties associated with it. This product is made from the flowers, leaves and stalks of hemp plants and contains less than .3 percent THC, which is the compound that causes users to feel high.
Hemp oil is often used for cooking and has a variety of benefits. It contains omega-3 fatty acids, which are beneficial for improving heart health. It also increases glutathione production in the body, which helps boost your immune system so you can fight off different kinds of diseases more easily.
CBD oil is also made from hemp and has many of the same benefits. It’s often referred to as CBD-rich hemp oil, CBD-hemp tincture or just plain old hemp extract. If you’re looking for a cannabis product that won’t get you high but still offers all of the health benefits of marijuana, this is your best option.
How Do I choose the right CBD oil cream?
Of course, the first thing you need to do when choosing a cannabis-based product is learning how much CBD or THC it contains. These two elements are only available in marijuana plants and both interact with your endocannabinoid system (ECS) through different pathways, which means that they can produce quite different effects.
Only products which have been tested by a third party should be considered, and the label should always indicate the exact amount of CBD or THC per dose. In addition to these two main factors, there are several other things you need to take into account when choosing a CBD cream for neuropathy in feet.
Type and concentration of terpenes.
Terpenes are essential oils that give cannabis strains their distinctive flavors, aromas and effects. Some terpenes have very specific properties for medical use. The best CBD creams will include a full spectrum of cannabinoids and terpenes to maximize benefits.
How much CBD is in the product? This is important to know before buying or consuming any cannabis-based product. Some people might need a simple topical cream while others will want something stronger like transdermal patches, capsules or vape pens.
A brand that has positive reviews and high ratings from customers should be your first choice.
And last but not least, CBD oils should be manufactured using extraction methods that don’t involve toxic solvents like propane and butane. These harsh chemicals can harm your health when they’re heated up.
1. Penguin CBD Cream
Image courtesy Penguin CBD
This topical CBD cream is designed to work no matter how you choose to use it.
Not only can you apply it directly to the painful areas of your feet, but you can also take it before bed so that the ingredients have time to absorb into your skin overnight. This means fewer side effects and more benefits from its moisturizing properties.
2. Everest CBD Full-Spectrum
Image courtesy Everest
The high grade of Everest’s full-spectrum CBD oil makes it perfect for your needs. They use naturally grown hemp, which means they have more natural ingredients and aren’t deprived like other brands. This is by far, one of the more excellent options of CBD creams for neuropathy in feet on this list.
3. R+R Medicinals
Image courtesy R+R Medicinals
This cream is designed to be used by individuals who want fast results. It uses all-natural ingredients like olive oil, beeswax, and CBD to give you the ultimate level of pain relief without any irritation or harmful side effects.
4. Verma Farms CBD Cream
Image courtesy Verma Farms
This is an all-natural topical cream that can be applied to any part of your body. It uses organic ingredients, including THC-free CBD so you know you will have a safe and pleasant experience with it. Plus, Verma Farms has made this product affordable so everyone can enjoy its benefits without having to spend too much money.
5. FOCL Relief Cream
Image courtesy FOCL
This CBD cream is designed to be used on all different areas of your body. It works to quickly reduce pain, soothe irritation, and relax muscles so you can feel comfortable again. It goes on nice and smooth without any greasiness or sticky residues that other creams leave behind.
6. Batch CBD
Image courtesy Batch CBD
This cream is made from 100% natural hemp oil that uses CBD to naturally relieve your pain. It works on any part of your body without causing irritation or uncomfortable side effects. Plus, it’s made with many organic ingredients that are safe for you and the environment.
7. Colorado Botanicals
Image courtesy Colorado Botanicals
Looking for an all-natural way to help with your chronic pain? Well look no further! This CBD oil is perfect if you’re just starting out or have naturally low tolerances and won’t give yourself too many side effects. Colorado Botanicals’ high-quality CBD oil is mixed with natural, organic MCT Oil (from coconut) which has a variety of health benefits.
8. Leaf Remedys Cooling Gel
Image courtesy Leaf Remedys
This cooling gel is made with 100% all-natural ingredients that feature CBD. It also includes hempseed oil, willow bark extract, and other organic elements to give you the ultimate comfort without any irritation or harmful side effects to your skin.
9. CBDfx Muscle and Joint Cream
Image courtesy CBDfx
If you’re looking for a CBD cream that will reduce your pain quickly, this is the one. It’s specifically designed to give quick relief from any sort of muscular or joint discomfort by using fast-acting ingredients like menthol and camphor.
10. Lord Jones CBD Body Oil
Image courtesy Lord Jones
Made from pure Icelandic water and all-natural ingredients, this CBD oil targets pain as effectively as pharmaceuticals but without the extra chemicals. The essential oils like lavender and bergamot nourish your skin and leave you feeling relaxed after a long day of work.
11. CBDfx Foot Care Set
Image courtesy CBDfx
This foot cream caters to individuals who are suffering from feet pain due to diabetes. It’s made with CBD oil and Vitamin E, which work together to promote healing while soothing any sort of discomfort you might be feeling. The peppermint scent works like aromatherapy for an extra boost of relaxation while also making it easier for the product to absorb into your skin.
12. CBDMedic Aches and Pain Relief
Image courtesy CBDmedic
This topical pain relief cream contains 10 mg of CBD isolate, which is the purest form of CBD available. It uses all-natural ingredients to keep skin healthy and nourished while reducing inflammation and sensitivity. This means no side effects like dryness or itchiness because it’s designed with your comfort in mind.
13. Vertly Lotion
Image courtesy Vertly
This product is made from 100% natural hemp oil that features over 1400 mg of CBD, terpenes, and other beneficial cannabinoids. The powerful combination of these ingredients helps promote the production of endorphins, which are your body’s natural painkillers.
14. Harmonious CBD Pain Salve
Image courtesy Harmonious CBD
This topical CBD cream is eco-friendly, vegan, and made from 100% all-natural ingredients. It’s also free of parabens and any other harmful chemicals like petroleum and formaldehyde. This means it won’t irritate your skin while still targeting the pain you’re feeling.
15. CBDistillery Oils
Image courtesy CBDistillery
If you’re looking for a product that will ease your pain with the most benefits, this is the one. It features up to 1000 mg of CBD, which is more than many other brands use in their products. This makes it perfect for individuals who need help with inflammation, anxiety, depression, and neuropathy in feet.
16. Pure Hemp Isolate Cream
Image courtesy Pure Hemp
This product is high-quality and tasty. It uses 100% pure hemp oil that has been extracted from the plant using natural methods for a healthy alternative to pain relief. Plus, it’s made without any extra ingredients or preservatives, making it safe for your skin.
17. BioTech CBD Oil Roll On
Image courtesy BioTech
This CBD oil contains 100% natural ingredients that work to reduce inflammation. It’s also made without any chemicals or preservatives that could do more harm than good for your skin. You can use it on any part of your body without worrying about the effects.
18. NuLeaf Naturals CBD Salve
Image courtesy NuLeaf Naturals
This salve is made with organic hemp oil that has been infused with essential oils for a soothing effect. It’s all-natural and doesn’t contain any chemicals or artificial ingredients that could irritate your skin. It comes in three different strengths for you to choose from depending on what you need relief from.
19. CBD.Co CBD Foot Care Bundle
Image courtesy CBD.co
This bundle is the perfect product for individuals who are looking to take control of their pain. The CBD oil works with your body to promote healthy feet while relieving any discomfort you might be feeling. Also, it includes a foot scrub and blanket so you can feel even more comfortable.
20. Aspen Green Muscle Relief Cream
Image courtesy Aspen Green
This muscle relief cream is made from 100% organic ingredients, which means you can trust it won’t irritate your skin or make you feel uncomfortable. Plus, it uses 2000 mg of CBD to help naturally manage the pain and soreness in your feet.
21. Level Select 2 CBD Sports Cream
Image courtesy Level Select 2
This cream is designed to be used by athletes who are tired of having their muscles ache after a workout. It uses an all-natural blend of ingredients that work together to relieve soreness and make your body feel good again.
22. Medterra Pain Relief Cream
Image courtesy Medterra
This cream is designed to use CBD and arnica to ease your muscles and make them feel great again. It also uses avocado oil, Shea butter, and many other organic ingredients to give you the ultimate level of comfort without any side effects.
23. cbdMD Cream
Image courtesy cbdMD
cbdMD’s broad-spectrum hemp extract provides relief from minor ailments while histamine dihydrochloride creates an enjoyable warming sensation to soothe your muscles overnight! Add in aloe vera with MSM as well as essential oils like arnica or oregano just waiting out there ready when you need them most – this cream has got everything needed at all times to soothe neuropathy in feet.
Is there a cure for neuropathy in the feet?
There are many different causes associated with neuropathy and many of these can be treated or cured.
Neuropathic pain is classified by the International Association for the Study of Pain as one of the most common types of chronic pain.
The treatment for neuropathy can be done in two ways- pharmacological management and non-pharmacological management. The doctors prescribe medications that work to manage neuropathy in the feet. This may include gabapentin, carbamazepine, or other antiepileptics.
The non-pharmacological management includes physiotherapy sessions where the doctors use ultrasound therapy, diathermy, and electrical nerve stimulation (TENS) among others to help relieve the discomfort in your feet. The patients are also advised to take measures like exercising, changing their lifestyle and diet habits.
There is no cure for neuropathy in the feet, but it can be managed with painkillers like ibuprofen or aspirin. There are creams available that claim to provide relief from the discomfort of neuropathy in the feet; they may contain ingredients like menthol or camphor. You can also opt for CBD oil and cream and get relief from this condition.
Can you put CBD oil on your feet?
Yes, you can apply CBD oil on your feet to give them a healthy glow or help relieve neuropathy. The oil is made of natural ingredients that will not cause any harm to the skin. It is safe for daily use and does not cause any irritation or crusting of the skin.
There are specific creams available in the market that contain CBD extracts for giving a healthy glow to the skin and relieving nerve pain on your feet. CBD oil is a good healer and can provide relief from pain, inflammation, and stiffness of joints. It also helps in smoothing scars left by injuries or accidents.
What is the maximum strength CBD cream?
Maximum strength CBD cream is the one that contains 20% of CBD oil in it. The rest of the ingredients comprise of natural products like beeswax, shea butter, coconut oil, and vitamin E.
This cream helps with faster absorption in your skin so that you can get quick relief from daily discomfort. Since maximum strength CBD creams contain higher amounts of CBD, they are slightly costlier than other products containing lower amounts.
The maximum strength creams give you immense relief from muscle pain, neuropathy in feet, skin allergies, or scars on your skin. You will find that the natural ingredients used to make this cream are good moisturizers for your skin and help keep it healthy.
In conclusion, it’s true that neuropathy in feet can be treated with CBD oil and cream. The oil and cream are made of natural ingredients that help relieve pain, inflammation, and stiffness. They also help cure scars left by injuries or accidents.
Furthermore, the maximum strength CBD cream helps with faster absorption in your skin to provide quick relief from daily discomfort.
However, it’s important to buy a cream that contains ingredients like menthol or camphor as these give a cooling sensation and will make you feel better for a longer period of time.
Best CBD Oil for Nerve Pain Reviewed in 2022
Neuropathy involves not only pain but also other pesky symptoms such as anxiety, nausea, and vomiting, as shown in studies on painful peripheral neuropathies. If nerve pain plagues every day of your life, things like muscle spasms, joint inflammation, and stiffness can become unbearable.
People who used up their conventional treatment options, but to no avail, have recently started switching to natural resources, such as CBD oil, for their nerve pain. According to recent studies, CBD may ease neuropathy and help individuals manage their symptoms in a safe and effective way.
These findings are promising for people with neuropathy, even though it’s too early to make definite statements. In this article, we’ll present the data from the current research on this subject on top of our industry overview, where we give our recommendations on the best CBD oil for neuropathy.
Best CBD Oils for Neuropathy
The quality of CBD oil is paramount for your results with neuropathy. Unfortunately, no two CBD oils are made the same; in fact, there’s a large degree of difference in quality between brands. There are many great companies committed to quality, but there’s an equal number of fly-by-night brands preying on uneducated customers.
Having been in the business for 7 years, we’ve tried a plethora of CBD oils from dozens of different brands. This year was even more demanding in terms of the tested products considering the continuously rising popularity of CBD.
We’ve selected the top 5 CBD oils for neuropathy from over 40 companies that offer CBD oil in three different types: full-spectrum, broad-spectrum, and isolate. Our ranking is based on the quality criteria such as hemp sourcing, extraction methods, third-party testing, and customer service.
1. Royal CBD (Best CBD Oil for Neuropathy)
Get 15% off all Royal CBD products. Use code “CFAH” at checkout.
|Potency||250 mg –2500 mg|
|Available Flavors||Natural, Berry, Mint, Vanilla|
|CBD per serving||8.3 mg – 83.3 mg|
Why Royal CBD is the Best CBD Oil for Neuropathy
Royal CBD was launched in 2018 in California by a group of cannabis aficionados with a vision to elevate the quality standards and customer service on the market after collecting their own experiences from the customer’s side. This premium brand offers full-spectrum CBD oil sourced from organic hemp and extracted with supercritical CO2. This method of extraction allows even high-potency oils to maintain the plant’s original chemical profile due to lower temperatures.
Royal CBD oil comes in four different strengths, including 250 mg, 500 mg, 1000 mg, and 2500 mg. For potencies between 250 mg and 1000 mg, you can choose between three flavored options, such as Mint, Berry, or Vanilla. The strongest version (2500 mg) is only available in the natural flavor, as adding flavorings would negatively impact the potency of CBD.
Speaking of high-potency oils, the 2500 mg bottle is my favorite product from Royal CBD. The hemp aftertaste is surprisingly mild because the oil has been infused into food-grade coconut-derived MCT oil. This adds another benefit because MCT oil also enhances the absorption of CBD.
If you experience nerve pain — whether regularly or from time to time (like me) — this potency will probably be your go-to choice. It has a deeply relaxing effect and can reduce inflammation for quite a long time after ingestion. I take it under the tongue, wishing the extract around my mouth to increase the surface area for absorption and minimize the amount of oil that passes through the gut.
- Sourced from non-GMO, Colorado-grown hemp
- Extracted with supercritical CO2
- Contains full-spectrum CBD
- Available in 4 strengths and 3 flavored options
- Up to 2500 mg of CBD per bottle
- Lab-tested for potency and purity
- 30-day money-back guarantee
- Slightly more expensive than the competition
- No vape products available
2. Gold Bee (Best Organic)
|Potency||300 mg – 2400 mg|
|Available Flavors||Natural, Honey-Kiwi|
|CBD per serving||8.3 mg – 33.3 mg|
About Gold Bee
Our second-best CBD oil for neuropathy comes from Nevada, but Gold Bee is a true maverick among other brands due to the unique honey flavor of its full-spectrum CBD oil, which the company produces from locally grown, non-GMO hemp.
The quality of ingredients — just as the honey flavor — are award-winning in my opinion. This CBD oil has a very natural flavor, with an actual honey aftertaste, which makes this product particularly enjoyable to use. There’s no tart, earthy taste that you can feel with the majority of CBD oils.
When it comes to easing nerve pain, I noticed similar results to what I got with Royal CBD, but due to the lack of high-potency oils in its lineup, Gold Bee is the runner-up in this compilation.
- Made from US-grown organic hemp
- Contains the full spectrum of cannabinoids and terpenes
- Up to 33 mg CBD/mL
- Good potency range for new users
- Lab-tested for CBD content and purity
- No high-potency oils
- Honey is the only flavored option
3. CBDPure (Top Transparency)
|Potency||100 – 1000 mg|
|CBD per serving||3.3 mg – 33.3 mg|
CBDPure is one of the most reputable US brands that specialize in making low-potency CBD oil, although the company has lately expanded their line up with a 1000 mg strength. This is a nice nod towards users who want to save more money on their CBD oil but their dosage doesn’t exceed 30 mg CBD daily.
CBD pure is also one of the most transparent companies on the market. The guys at CBDPure explain every step of how their oils are made, and surprisingly for low-potency extracts, these products provide decent results when it comes to pain relief. The only reason CBDPure scores third place on this list is because of the higher prices. Some users may find these oils less affordable than other premium brands in the long run.
Want to try if CBDPure products will work for you? The brand has a 90-day money-back policy. You can return the product for a full refund within 90 days if you’re unsatisfied with the results.
- Sourced from Colorado-grown organic hemp
- Extracted with CO2
- 4 strengths to choose from
- Lab-tested for potency and purity
- 90-day return policy
- No high-potency oils
- Only two forms of CBD available
- Priced higher than competitors
4. Hemp Bombs (Best CBD Isolate)
|Potency||125 – 4000 mg|
|Available Flavors||Natural, Acai Berry, Orange Creamsicle, Peppermint, Watermelon|
|CBD per Serving||4 – 133 mg/mL|
About Hemp Bombs
When it comes to the best isolate-based CBD oil for nerve pain, Hemp Bombs offers the widest selection of products. The company has covered the entire potency range for CBD oils, offering up to 4000 mg of total CBD.
This oil is a good alternative for people with neuropathy who, for some reason, want to abstain from taking any THC in their product while getting a decent dose of CBD per serving. Full-spectrum products contain up to 0.3% THC; while this isn’t enough to get the user high, CBD isolate is completely free of THC. This trait is particularly important for CBD users who are regularly tested for drugs at work.
Because CBD isolate is made from 99% pure CBD, it has no aroma and flavor, which makes it more versatile thankful-spectrum extracts.
On the other hand, you won’t get the synergy from other cannabinoids and terpenes with CBD isolate, so this company may not have the best products if you want to benefit from whole-plant extracts in your supplementation.
- Made from organic hemp
- Extracted with CO2
- Third-party tested for potency and purity
- Up to 4000 mg of total CBD
- 5 potency options to choose from
- Flavored with synthetic ingredients
- No synergy from other cannabinoids and terpenes
- Most people don’t need so much CBD oil in their routine.
5. CBDistillery (Most Affordable)
|Potency||250 mg – 5000 mg|
|Potency||8.33 – 166 mg/mL|
CBDistillery is one of the most reputable companies in the American market. The company has been selling premium CBD oils for over 5 years, becoming one of the largest brands in the USA. Started by a group of Colorado natives with a mission to produce high-quality CBD products affordable for everyone, CBDistillery offers two types of hemp extracts: full-spectrum and broad-spectrum (pure oil). Similar to the full-spectrum CBD, broad-spectrum extracts contain CBD along with other non-intoxicating cannabinoids, but without any traces of THC. The THC is removed from the product after initial extraction.
The CBDistillery CBD oil comes in a wide range of concentrations, from 250 mg to a massive 5000 mg of CBD per bottle. The strongest version provides 166 mg of CBD per milliliter, which usually lasts for months.
As for the results, I was satisfied when it came to pain and irritation. I also noticed that my stomach was calmer than before taking this oil. However, there’s a reason why I’ve placed CBDistillery at the very bottom of this compilation. Unlike competitor brands, this one doesn’t use organic hemp plants.
So, CBDistillery may not sell the best CBD oils out there, but considering the price, these are hands down the best CBD oils for neuropathy in their range.
- Available as full-spectrum or broad-spectrum CBD
- 5 strengths to choose from
- Up to 166.6 mg of CBD per mL
- Third-party tested for CBD content and purity
- Very affordable
- Sourced from non-organic hemp
- No flavored oils
What Causes Neuropathic Pain?
Neurons within the body carry signals to the brain, including pain signals. While this sensation is anything but pleasant, it has one important purpose — to prevent injuries. Once you place your foot on a hot surface, the painful sensation will warn your brain against the danger.
That’s how the process is supposed to work in healthy people. But with patients suffering from neuropathic pain, that nervous signaling system falls out of whack. In simple words, your brain receives pain signals, and you feel the pain, but there’s no obvious cause of that feeling. And because of this, it’s difficult to find an immediate remedy.
What’s the matter with those wayward nerves? Most of the time, it’s the result of damage from a disease or physical injury, including:
- Physical injuries: this is a very common cause of neuropathic pain, in which nerves get crushed, compressed, or severed.
- Shingles: this condition is another cause of neuropathy, one that can transform into a painful disease called postherpetic neuralgia. This type of nerve pain can be particularly severe and immediate.
- Cancer and other tumors: As they grow, tumors can constrict the surrounding nerves. Cancer cells can also grow out of the nerves on their own. Sometimes, chemotherapy or radiation can damage nerve cells too, resulting in neuropathic pain.
- HIV: this autoimmune viral condition can lead to painful nerve damage. Nerve pain actually affects around one-third of HIV patients, and nerve within the hands and feed is one of the first symptoms that occur. Antiretroviral treatments can also lead to nerve damage that triggers pain.
- Diabetes: if you have diabetes, you have a higher risk of suffering from nerve injury. At some point, consistently high levels of glucose accompanied by hypertension can damage the nerves.
These are just a few conditions that can cause nerve damage and lead to neuropathic pain. Others include vitamin deficiencies, hormone balances, constant exposure to stress, and more. In some rare cases, nerve pain can just occur without a reasonable explanation.
Experts on Neuropathic Pain and Its Prevalence
Nerve pain derives from the central or peripheral nervous system. These networks are made of the brain and spinal cord. The spinal cord runs down from the brain and through the center of the spine. The nerves stretching from the spinal cord and traveling throughout the limbs and head are the peripheral nervous system. All these structures work together, constantly exchanging signals about your body.
Dr. Suraj Muley, an esteemed neurologist and director of the neuromuscular division at Barrow Neurological Institute in Phoenix, there are several common points for patients with neuropathy. They usually include electric-like, shooting pain with an ice-cold sensation, sensitivity to touch, and feelings of numbness.
The nerves are important players for any kind of pain, as well as other types of sensations. According to Dr. Ryan Jacobs, a neuromuscular neurologist, pain messages are sent by the nerves. This often happens as a result of inflammation or injury that causes damage to body tissues such as skin, bones, or muscles. However, nerve pain refers to damage caused by an injury to the nerves on their own. He also added that in some cases, it can be damage to one significant nerve or a few minor ones that can contribute to a widespread nerve injury.
How Can You Determine the Cause of Neuropathic Pain?
Doctors first conduct an interview with their patients, asking about the symptoms, history of medical conditions, and running a short examination. A physician may check for such things as sensory loss using a pinprick on different parts of the body. If the patient doesn’t feel the impulse from the pinprick or other things, that could indicate neuropathy, as said by Dr. Eva Feldman, a professor of neurology at the University of Michigan.
Aside from the interview and initial examination, your doctor may recommend conducting additional testing, such as bloodwork, to gain a bigger picture of what’s the reason behind the neuropathic pain in your case. You may be asked to run a test called hemoglobin A1C to check your average blood sugar levels and exclude the possibility of diabetes. The doctor may also check if you have sufficient vitamin B12 levels; deficiencies in this vitamin can lead to nerve damage and numbness.
Treatment Options for Nerve Pain
Treating neuropathy is tricky due to its specific nature and the exact cause of the problem. When nerve pain is triggered by a condition such as HIV, diabetes, or cancer, tackling the underlying disease is undoubtedly the priority. However, this treatment won’t necessarily help with your neuropathic pain. Nerve pain may require a dedicated treatment, one that is different from the treatment for the disease that’s causing it.
Doctors typically use prescription painkillers depending on the type and severity of neuropathic pain. However, people can build a tolerance to the active ingredients in these medications, let alone the risk of addiction and several dangerous side effects, including lethal overdose.
Experts believe that 40 million Americans struggle with nerve pain. The impact of neuropathy on modern society is enormous, and for many of us, the potential side effects of pharmaceutical medications outweigh their benefits. It’s totally understandable that people have started to look for natural alternatives such as CBD oil.
Using CBD is an option for treating many types of pain. Studies have already highlighted a few mechanisms responsible for the versatility of CBD in mitigating pain signals. But can it help with neuropathic pain?
Why Some People Are Choosing CBD Oil for Neuropathy
Some forms of neuropathy can be easily treated and sometimes cured. If neuropathy is incurable, the treatment should aim at preventing further damage to the nerve and controlling symptoms.
CBD has been shown to have some therapeutic qualities that might assist patients with neuropathic pain and other symptoms linked to neuropathy such as suppression of the nerves like Carpal Tunnel Syndrome.
CBD vs Anxiety, Chronic Pain, and Vomiting
According to the American Chronic Pain Association, neuropathic pain is the type of chronic pain that occurs in the nerves in the peripheral nervous system due to injury or damage.
Anxiety, nausea, pain, and vomiting are telltale neuropathic symptoms, as noted by a study on painful peripheral neuropathies that was published in Current Neuropharmacology.
Research has shown that CBD may be useful in easing different types of chronic pain. Neuropathic pain falls into this category, but unlike other chronic pain conditions, neuropathy is particularly difficult to treat, according to the author of a paper on neuronal mechanisms of neuropathic pain.
On top of acting as a neuroprotectant, CBD also has some other therapeutic properties, including antiemetic and anxiolytic effects.
CBD vs Inflammation and Muscle Spasms
Neuropathy often results from chronic inflammation, such as in diabetes, which is the number one cause of neuropathic pain in the United States.
Neuropathy can also derive from autoimmune diseases, such as arthritis or lupus. Autoimmune diseases are linked to a higher risk of hypertension and cardiovascular problems.
CBD can inhibit inflammatory and neuropathic pain caused by autoimmune diseases. In a 2016 animal study published in the European Journal of Pain, topical application of CBD helped reduce pain and inflammation triggered by arthritis.
CBD’s remarkable anti-inflammatory effects were also demonstrated in vivo in a 2018 study published in the Journal of pharmacology and Experimental Therapeutics.
Moreover, CBD may help relieve muscle spasms, which is a common feature of nerve damage, often marked by uncontrolled and painful muscle twitches.
Sativex, a combined oral spray consisting of THC and CBD in a 1:1 ratio demonstrated high efficacy in helping with pain management in patients with neuropathic pain caused by nerve damage, peripheral neuropathic pain, rheumatoid arthritis, advanced pain, and spasticity from multiple sclerosis. The results were published in Neuropsychiatric Disease and Treatment.
Similar results were observed in a review of similar studies published in The Cochrane Database of Systematic Reviews in 2018.
The above review examined hundreds of studies on using cannabinoid-based medicines on neuropathic pain in adults. While not all of them turned out positive, there was significant evidence that cannabinoids could reduce nerve pain and other symptoms of this condition.
How Could CBD Oil Help With Neuropathy?
The endocannabinoid system (ECS) is essential for understanding how CBD works to relieve neuropathy. The health benefits of CBD and other cannabinoids result from their interaction with the body’s ECS, which is the major regulatory network in all mammals.
The ECS controls a wide range of biological processes, including immune response, sleep, mood, appetite, metabolism, memory, and pain sensation.
This system consists of two types of cannabinoid receptors — CB1 and CB2 — which are found in specific parts of the body.
CB1 receptors are mostly found in the brain and central nervous system, but there are some concentrations of these receptors in reproductive organs, lungs, liver, retina, and urinary tracts.
CB1 receptors are involved in-memory processing, pain sensation, mood, sleep, and motor regulation. Their activation is linked to neuroprotective responses, suggesting that the cannabinoids acting on CB1 receptors could help in the prevention and treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.
When it comes to CB2 receptors, these are primarily located on the surface of the immune system cells and their associated structures. The activation of CB2 receptors is said to produce an anti-inflammatory response, minimizing damage to nerves and reducing pain.
The above qualities have been found to be potentially helpful for treating autoimmune conditions, such as Crohn’s disease, arthritis, inflammatory bowel syndrome, and chronic inflammatory demyelinating polyneuropathy (CIDP).
CBD doesn’t bind to any of the cannabinoid receptors; it does, however, act indirectly on them, causing similar actions as the substances that typically stimulate the receptor.
CBD also has more than 65 molecular targets. It can interact with other receptors in the body, such as the 5-HT1A serotonin receptor. Serotonin is a neurotransmitter that controls feelings of well-being and emotional stability. It can also modulate nausea, anxiety, and pain.
Pros & Cons of Using CBD Oil for Neuropathy
- Can help with symptoms such as inflammation, anxiety, pain, nausea, vomiting, and muscle spasms
- Has been recognized as safe by major health agencies including the WHO
- Can be purchased without a prescription (locally and online)
- Not approved as an official treatment by the FDA
- Can interact with 70-80% of prescribed medications
- Side effects include dry mouth, drowsiness, fatigue, and changes in appetite
- Products sold online and in local stores are mostly unregulated
CBD vs Other Alternative Treatments for Nerve Pain
Alternative treatments for patients with neuropathy include the use of capsaicin, primrose oil, and amino acids.
Capsaicin is an analgesic compound found in hot peppers. A study examining the use of an 8% capsaicin dermal patch found that almost 71% of participants with cancer-related neuropathic pain experienced 90% relief.
Primrose oil may help ease neuropathic pain in people with diabetes, as stated by Mayo Clinic in an article regarding peripheral neuropathy diagnosis and treatment.
According to the same clinic, amino acids, such as acetyl-L-carnitine, may help people after chemotherapy as well as patients with diabetes.
Is there a way to combine the benefits of the above compounds with the analgesic effects of CBD?
Some CBD products come in the form of salves infused with capsaicin. In these CBD products, the capsaicin supports CBD’s natural pain-killing benefits to help with problematic spots on the body.
As for hemp oil, which is often added to CBD topicals, it’s an excellent source of essential fatty acids and amino acids. You can also look for topicals infused with primrose oil for enhanced anti-inflammatory effects.
How to Use CBD Oil for Neuropathy?
Figuring out how to use CBD oil for neuropathy can help you maximize your results. Sometimes, cream or gel maybe is your best option if you want to completely avoid ingesting the oil.
However, if you want to approach the problem from two different angles, we recommend that you use full-spectrum CBD drops as your primary means of CBD oil.
CBD oil should be applied under the tongue for approximately 60 seconds before swallowing. This method of administration ensures that the CBD absorbs into the bloodstream through sublingual capillaries, avoiding the first-pass effect in the liver.
Alternatively, you can take capsules or edibles if you have problems holding the oil in your tongue, but CBD taken orally takes more time to kick in. Capsules and edibles are a great option if you want to ease nerve pain in social settings, or when you need longer-lasting relief at the cost of delayed onset.
If you need something to help with localized pain, then a topical such as warming salve could provide some relief. Usually, people who take CBD for neuropathy combine the oil (or edibles) with topical products.
CBD Dosage for Neuropathic Pain
Everybody will react to CBD differently because we’re not made the same. You need to ask yourself a few questions.
How much pain am I in?
Is it chronic pain or does it just happen randomly throughout the day?
Do you want to take CBD oil to function better or take the nerve pain away entirely?
Other important considerations for CBD dosage include your weight, age, metabolism, overall health, and prior experience with CBD oil.
Customers usually take CBD oil as well as use a topical about 1–3 times a day. In order to find the right dose and strength for yourself, you’ll need to go through some trial and error, starting at the lower end of the recommended serving size, and slowly making your way up to the point where you experience a significant difference in your symptoms.
Safety and Side Effects of CBD Oil
CBD has a well-established safety profile. It can be taken under the tongue in doses of 300 mg – 1500 mg daily for up to several weeks. Dosage recommendations for prescribed cannabidiol (Epidiolex) range from 10 to 20 mg per kg regularly.
Some rumored side effects of CBD oil include dry mouth, dizziness, changes in appetite, and sedation resulting from a temporary drop in blood pressure. Signs of diarrhea have also been reported in some patients, but this is a very rare adverse reaction.
Final Thoughts on Using CBD Oil for Neuropathy
CBD has demonstrated the ability to reduce neuropathic pain in many studies. Not only that, but CBD can also help with other neuropathic symptoms, such as anxiety, nausea and vomiting, spasms, and inflammation.
As more studies are being conducted in this area, CBD may become the go-to treatment option for neuropathy in the future. However, CBD isn’t the only cannabinoid found in cannabis that can help alleviate neuropathy.
Full-spectrum CBD oil contains all phytonutrients naturally found in hemp, including terpenes, flavonoids, and trace cannabinoids. These compounds work together to amplify the health benefits of each cannabinoid, producing the “entourage effect.”
This is the best type of CBD for neuropathy. However, regardless of the product choice, make sure to check all marks on the quality checklist, including the source of hemp, extraction method, and third-party lab testing. If you don’t have the time to do your own research, you can use our recommendations from above.
Let us know in the comments if you use CBD oil for neuropathy — and how it works for you!
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
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The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities
Background: Peripheral neuropathy can significantly impact the quality of life for those who are affected, as therapies from the current treatment algorithm often fail to deliver adequate symptom relief. There has, however, been an increasing body of evidence for the use of cannabinoids in the treatment of chronic, noncancer pain. The efficacy of a topically delivered cannabidiol (CBD) oil in the management of neuropathic pain was examined in this four-week, randomized and placebocontrolled trial.
Methods: In total, 29 patients with symptomatic peripheral neuropathy were recruited and enrolled. 15 patients were randomized to the CBD group with the treatment product containing 250 mg CBD/3 fl. oz, and 14 patients were randomized to the placebo group. After four weeks, the placebo group was allowed to crossover into the treatment group. The Neuropathic Pain Scale (NPS) was administered biweekly to assess the mean change from baseline to the end of the treatment period.
Results: The study population included 62.1% males and 37.9% females with a mean age of 68 years. There was a statistically significant reduction in intense pain, sharp pain, cold and itchy sensations in the CBD group when compared to the placebo group. No adverse events were reported in this study.
Conclusion: Our findings demonstrate that the transdermal application of CBD oil can achieve significant improvement in pain and other disturbing sensations in patients with peripheral neuropathy. The treatment product was well tolerated and may provide a more effective alternative compared to other current therapies in the treatment of peripheral neuropathy.
Keywords: CBD; cannabis sativa; diabetic neuropathy; hemp; nerve pain; review..
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