Cbd oil for pain mayo clinic

Is CBD safe and helpful? More human studies needed, says Mayo Clinic study

26 Aug 2019 — A growing body of pre-clinical and clinical evidence suggests that cannabidiol (CBD) oils may hold promise for treating conditions such as chronic pain and opioid addiction, according to a review of the latest research on the subject, to be published in September in Mayo Clinic Proceedings. However, the authors note that more research involving humans is needed before health care providers can definitively classify CBD as helpful and safe. With their latest findings, the researchers are advising physicians to expand their knowledge on the cannabis extract to best advise their patients.

CBD oils and products have become increasingly popular with consumers as ways to find relief from aches and pains, anxiety, sleep disturbances and other chronic issues. However, most studies of the cannabis extract have been conducted on mice.

“There are many intriguing findings in pre-clinical studies that suggest CBD and hemp oil have anti-inflammatory effects and may be helpful with improving sleep and anxiety,” says Brent Bauer, M.D., Director of Research for the Mayo Clinic Integrative Medicine program. “But trials in humans are still limited, so it is too early to be definitive about efficacy and safety.”

Dr. Bauer asserts that there is reason for concern about a growing number of reports of liver injury in patients who have used CBD products. With increasing patient interest in CBD and hemp oil products, it is important that clinical research moves ahead to better understand their potential value and safety, he highlights.

“Careful selection of a health care product is crucial, and though these products do not have Food and Drug Administration (FDA) approval for therapeutic use, patients continue to ask for them and use them. Physicians need to become better informed about these products, and it’s important that human trials examine issues of efficacy and safety,” says Dr. Bauer.

See also  Cool vape pens for cbd oil to work

With CBD a hot consumer trend, physicians may find it easy to dismiss it as unproven and untested, note the researchers. Dr. Bauer encourages health care professionals develop expertise on these products and not to easily dismiss their patients’ interest in CBD.

“We encourage physicians to not disregard their patients’ interest in these products and keep both a clinical curiosity and a healthy skepticism about the claims made,” he says. “Chronic pain management continues to challenge patients and physicians, and these therapies are a promising area that needs more research. For patients struggling with chronic pain, physicians taking time to listen to them and address their questions compassionately but with an evidence-based approach can help them make informed decisions.”

The variety of CBD and hemp oil products, and the limited regulation of these products, is a concern for health care professionals, according to the study. The variability of state laws regarding production and distribution of hemp and CBD products adds to the complexity of decision-making for consumers and physicians.

No rigorous safety studies have been done on “full spectrum” CBD oils, which contain a variety of compounds found in the hemp plant, not just CBD. Moreover, there are important distinctions between marijuana, hemp and the different components of CBD and hemp oil, and some clinicians may not be aware of them, as highlighted by coauthor Karen Mauck, M.D.

“Other than Epidiolex, a purified form of plant-derived CBD which was approved in 2018 for treatment of severe forms of epilepsy, all other forms of CBD are not approved by the FDA but are sold in a variety of formulations, including oral or topical oils, creams, sprays and tablets,” says Dr. Mauck. “They contain variable amounts of CBD, may contain other active compounds and may have labeling inaccuracies. Before using CBD or hemp oils, it’s important to consult with your physician about potential side effects and interactions with other medications.”

See also  How to use cbd oil for dog ear infection

The legalization of marijuana for medicinal purposes has spurred intense interest by consumers in over-the-counter products containing CBD and hemp oil, which are now available in a broad range of edible, topical and vapable formats.

By Benjamin Ferrer

To contact our editorial team please email us at [email protected]

If you found this article valuable, you may wish to receive our newsletters.
Subscribe now to receive the latest news directly into your inbox.

Understanding CBD (Cannabidiol) for Back Pain

Cannabidiol, commonly referred to as CBD, is a new and relatively understudied treatment for pain, including back pain. Studies suggest it may help relieve inflammation, which is often a factor in chronic back pain. 1

CBD is available in many forms; topical creams and gels have shown promising results for inflammation and neuropathy, which may make them a good option for back and neck pain. 2

CBD requires more research in order to prove and explain its effectiveness as well as to better understand potential side effects (especially long-term) and potential drug interactions.

What Is CBD?

CBD oil is derived from a plant called cannabis sativa. The plant has over 100 chemical compounds, called cannabinoids, that have a range of effects, including anti-inflammatory and analgesic (pain relieving) qualities.

The cannabis sativa plant has two main varieties that are grown for specific purposes:

  • THC content. THC is the compound associated with the “high” feeling of marijuana use.
  • Industrial (non-drug) uses. This form of the plant contains trace amounts of THC (less than .03%) and can be used to make paper, clothing, and some building material. This variation of the cannabis plant is called hemp.
See also  Cbd oil for dogs dispensary slem

While CBD is present in both varieties, many of the CBD products available to consumers are from the hemp plant. CBD does not come with the high or psychogenic effects of marijuana.

Ways CBD Treats Back Pain

Research indicates that CBD may reduce back pain by:

  • Reducing inflammation 3
  • Combating anxiety, often associated with long-lasting or chronic back pain 4
  • Helping with sleep and improving overall state of relaxation 5

Some studies suggest that CBD can have an effect on how an individual perceives pain, but more robust research is needed. CBD is generally considered a full-body treatment, which means that it does not target back pain specifically—except in the case of topical products—but contributes to an overall feeling of relaxation and pain relief.

Advocates of CBD believe it can be used to treat a range of conditions in addition to back pain, such as anxiety-related disorders. 5

Potential Risks and Side Effects of CBD

Cannabidiol, even in high amounts, is generally safe. Side effects from CBD may include:

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Low blood pressure

More severe side effects, while rare, include:

  • Mental confusion
  • Nausea
  • Vomiting
  • Diarrhea

As with other natural products, there is potential for adverse reactions when taken with other medications, especially those that come with grapefruit warnings, such as certain blood thinners. These warnings indicate that certain medications should not be taken with products containing grapefruit.

CBD use prior to surgery

Before having surgery, all cannabis use, including CBD and marijuana, should be disclosed to the surgeon or anesthesiologist. A recent study suggests that cannabis use may have an effect on medications used to sedate patients. 6