Cbd oil for stomach migraines

Marijuana and CBD Oil

Some people use marijuana, or forms of the cannabis plant such as CBD oil, to treat migraine. Cannabis has been used for thousands of years as a natural remedy for a number of conditions. While there are not enough high quality studies to support the use of marijuana for migraine, there is anecdotal (based on people’s experiences) and preliminary evidence that cannabis has been helpful for those with migraine. More trials are needed before marijuana can be considered a standard treatment for migraine. 1

What is marijuana and is it legal?

Traditionally, the smoking form of cannabis has been called marijuana. Today, some oral forms are also called marijuana. Topical forms that you rub into your skin are more often known as CBD oil as CBD is the active ingredient. 1,2

Cannabis for recreational and medicinal use is illegal under federal law. However, several states allow medical marijuana, and a few states have legalized recreational use. Each individual should talk with their doctor and learn the laws of the state they live in before using medical marijuana.

What are the differences between CBD and THC?

While there are over 400 different compounds (called cannabinoids) in the cannabis plant, the two most often studied are THC (delta-9-tetrahydrocannabinol) and CBD (cannabidiol). 2

THC is thought to reduce nausea and pain, and increase appetite. It may also produce psychological effects like euphoria, anxiety, and altered sensory perception, which can make users feel “high” or intoxicated. CBD (cannabidiol) does not cause intoxication. It does produce sedative effects that can help reduce pain, convulsions, nausea, and inflammation. There are a variety of preparations with varying doses of CBD and THC.

More studies are needed to decide if oral, inhaled, or topical forms of marijuana work best for which type of migraine and at what doses. 1

How does medical marijuana work in the body?

Researchers have discovered that the human body has an endocannabinoid system (ECS). “Endo” means internal or within the body. The ECS is distributed throughout the body. It plays a part in regulating many functions, including pain, mood, appetite, and the movement of the gastrointestinal system. The ECS includes the cannabinoids the body produces, the receptors on which they act, and the enzymes that are involved. 3

Studies on medical marijuana and migraine

Research on marijuana has been limited, due to the federal regulations and lack of funding. However, there have been recent studies on the use of cannabis or medical marijuana in people with migraine.

Migraine attacks decreasing from medical marijuana

In 2016, a study reviewed past data from 121 adults with migraine who were recommended either a migraine preventive drug or medical marijuana by their doctor. The study found that migraine attacks decreased from 10.4 to 4.6 a month with the use of medical marijuana. The types of marijuana used varied. Plus, many patients used more than one form and used it daily as a prevention strategy. Inhaled forms of marijuana were used most often as an acute strategy for migraine attacks and were reported to help ease symptoms. 2

The challenges of this study are that the types of doses of marijuana varied. This makes it impossible to know which form or dose worked best as a preventive or acute treatment. However, the study offers interesting data for future studies.

Community Poll

Was marijuana effective in relieving your migraine symptoms?

Cannabis for prevention and acute treatment of migraine

In 2017, Italian researchers provided more evidence on the use of cannabis for both prevention and acute treatment of migraine. The researchers first studied the proper dose of cannabis. A group of 48 people with chronic migraine were given oral doses with different levels of THC and CBD. Investigators found that at an oral dose of 200 mg, acute pain dropped by 55 percent. In phase 2 of the research, 79 people living with chronic migraine were given either a daily dose of marijuana or amitriptyline (a common antidepressant used as a treatment for migraine). The participants were also able to use 200 mg of marijuana for acute attacks. 4

After 3 months, those who received marijuana had a 40.4 percent reduction in migraine attacks compared to 40.1 percent of those who received the antidepressant. Researchers also found that the medical marijuana used for acute treatment reduced pain intensity by 43.5 percent. The most common side effects were drowsiness and difficulty concentrating. In addition, many participants reported less stomach aches and muscle and joint pain. 4

Another study in Europe found that 10.2 percent of people with migraine self-medicated with marijuana. Results were varied, with some people reporting that low doses helped relieve migraine while higher doses triggered headaches. 3

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Side effects and other precautions

Marijuana is not approved by the U.S. Food & Drug Administration. Because marijuana is not tightly regulated the way approved drugs are, it is difficult to list side effects because its strength and purity may vary with each use.

The long-term negative effects of medical marijuana are not known. Few studies have been conducted on the long-term safety of cannabis, and those that have been completed are often conflicting or are of poor quality. 1

Short-term side effects of medical marijuana are better understood and include:

  • Temporary impaired short-term memory and concentration
  • Increased in anxiety or paranoia
  • Possible physical or psychological dependence or addiction
  • Impaired motor skills like driving

These are not all the possible side effects of marijuana. Patients should talk to their doctor about what to expect with treatment with marijuana.

Who should not take marijuana?

If you are pregnant, breastfeeding, or plan to become pregnant, or are breastfeeding, you must consult your doctor before taking any supplement. It is well-known that smoking endangers the health of developing babies and should be avoided by pregnant women. The effects of marijuana have been studied in pregnant or breastfeeding women, and it is not recommended to take marijuana as it can pose a danger to the unborn child. 6

Community Poll

How would you rate the side effects you experienced with marijuana?

As always, the best source for advice on treating migraine is your own migraine specialist. These descriptions of natural remedies are provided only for informational purposes. You should begin no medication or supplement without first checking with your health care provider and should let them know of any other prescriptions, OTCs, and herbals you are taking to ensure there are no interactions.

Is CBD for Migraine Really All It’s Cracked up to Be?

Your Guide to Research, Risks, and How to Get Started

Medical Review by Dr. Eric Baron and Dr. Nathaniel Schuster (headache specialists)

Cannabinidiol (also known as CBD) has taken the wellness community by storm. Proponents claim CBD products like CBD oil are something of a “cure-all,” treating every condition from stomach aches to mental illness.

CBD for Migraine management is just one of many uses associated with this new health craze.

CBD is so popular in fact, that MarketWatch predicts it could become a $22 billion industry by 2022 in the US alone

Press Release: Rising Popularity in CBD Based Products Now Projected To Outpace Marijuana. Market Watch. Apr 25, 2019

The industry is well on its way to hitting this goal – 28% of the public use CBD on a daily or as-needed basis

Press Release: New Acosta Report Finds 28 Percent of Consumers Use CBD Products Daily or As-Needed. Yahoo Finance. 11 Sept 2019.

Because of its popularity, you’ve probably come across discussions or advertisements for CBD or CBD oil.

The key question is: can it help you manage Migraine?

What You Need to Know About CBD for Migraine

CBD for Migraines has received little attention from the scientific community. This in part due to laws prohibiting cannabis research in the US.

Baron, E.P., Lucas, P., Eades, J. et al. Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort. J Headache Pain 19, 37 (2018)

Today, over half the US states and the District of Columbia have legalized marijuana for medical purposes, although it is still not permitted under federal regulations. Laws around the world vary.

The good news is that research studies are being conducted right now. We should know more soon.

Before jumping on the CBD oil train, it’s important to arm yourself with the facts. This article will provide you with all of the info you need to work with your healthcare provider to make an informed decision about CBD for Migraine.

This guide will cover:
  • What CBD is and how it works
  • What research is available on CBD and Migraine
  • Tips for trying CBD

What is CBD?

CBD stands for “cannabidiol.” It is one of two major chemical compounds (cannabinoids) found in cannabis plants. The other is tetrahydrocannabinol, or THC, for short.

Despite CBD’s recent popularity as a natural remedy, experts have known of its existence for some time. In 1940, Dr. Roger Adams and colleagues at the University of Illinois isolated CBD from hemp oil for the first time.

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Thanks to the illegal status of cannabis in the US, early research didn’t go as far as uncovering the medicinal properties of CBD.

How CBD Interacts with the Human Endocannabinoid System

Dr. Eric Baron, a headache specialist at the Cleveland Clinic, spoke about cannabis during the 2019 Migraine World Summit

Interview transcript: Dr. Eric Baron. The Latest on Medical Marijuana for Migraine. Migraine World Summit. 2019.

“The endocannabinoid system is a natural system in our body,” he explained. “It is involved in virtually all organ systems, and it helps to regulate homeostasis and normal physiological functions in the body throughout most of the organ systems.

It’s very involved in the nervous system — the central and the peripheral nervous system — brain, spinal cord, the nerves.”

“The endocannabinoids are the neurotransmitters that work within this endocannabinoid system,” said Dr. Baron.

External cannabinoids like CBD and THC interact with this system the same way these endocannabinoids do, he explained.

Will CBD Get Me High?

CBD is not intoxicating, meaning you won’t get high inhaling or ingesting it. The high, commonly associated with marijuana, comes from its chemical counterpart, THC.

The World Health Organization put out a statement in 2017 saying that CBD exhibits no concern for abuse, dependence, or public health issues

World Health Organization. Cannabidiol. 2017.

. In January 2018, the World Anti-Doping Agency (WADA) removed CBD from its prohibited list, no longer banning use by athletes.

Hemp vs. Marijuana: Clearing up the Cannabis Confusion

One thing you might find confusing is that the word “cannabis” is often used to refer strictly to marijuana. However, this simply isn’t the case.

Cannabis isn’t a plant, but rather a plant genus that belongs to the family Cannabaceae. Within that genus, we have Cannabis Sativa. This includes both hemp and marijuana.

Headache specialist Dr. Stephen Silberstein explains, “In marijuana, unless we know the components of it and we have a consistent formulation, we can’t honestly ask our patients whether it works or doesn’t work, because we don’t know what they’re getting. That’s the problem

Interview transcript: Dr. Stephen Silberstein. Cannabis for Migraine. Migraine World Summit. 2018.

He explains that cannabis is a plant, like corn or tomatoes, with dozens of varieties.

So how do botanists separate hemp from its THC-rich cousin? They divide them into chemotypes. A chemotype refers to plants that are physically and genetically similar, but chemically different.

There are three Cannabis Sativa L. chemotypes, appropriately labeled as I, II and III.

Chemotype I is the high-THC cannabis (a.k.a. marijuana) that we all know best. It contains very little CBD.

Chemotype II covers plants that have relatively equal amounts of THC and CBD.

Chemotype III refers to cannabis used strictly for its fibres, rather than its cannabinoids (up until hemp-based CBD supplements came along). In other words, this is industrial hemp.

CBD can be extracted from either hemp or marijuana.

Where Can I Find Legal CBD and CBD oil?

CBD and CBD oil are widely available online and in stores, but which forms are legal?

If you get your CBD from a small supplement company, odds are that they’re not licensed to grow hemp or sell its derivatives. The problem with buying products like CBD oil online is that there is no way to know if the industrial hemp comes from a licensed source.

Major U.S. stores like Wal-Mart, Walgreens, Kroger, and CVS have all jumped on the CBD bandwagon, and are likely adhering to regulation

Lavita, Angelica. Kroger to sell CBD products in nearly 1,000 stores. CNBC. 11 June 2019

Your second option is to get CBD sourced from marijuana, but access varies from state to state. Currently, marijuana is medically legal in 33 states in the US, 11 of which allow it recreationally, too

Rense, Sarah. Here are all the states with legal cannabis. Esquire. 27 June 2019.

In order to purchase marijuana-sourced CBD, you need to visit a local dispensary. Never buy marijuana products online from “gray market” sources.

These are basically unregulated dispensaries operating outside the law. Although these illegal Internet storefronts seem legitimate, their product is grown or obtained illegally.

Dr. Silberstein warns:

“On the street, there’s a lot of synthetic marijuana known as K2 and other things. They’re not marijuana. They’re chemical derivatives that are very potent, and most of the adverse events and deaths attributed to marijuana have been due to the fact that marijuana has actually been spiked with K2 or spice. So you never know what you’re getting.”

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The safer, legitimately-produced products, he notes, are the non-smoked varieties given through alternate means of delivery, such as creams and tinctures (more on these below).

Will CBD Show Up on a Drug Test?

No, it shouldn’t. Given CBD’s benign nature, employers and law enforcement officers have no interest in testing for it specifically.

However, many CBD products contain minute traces of THC, which might cause complications with an employer. Although the trace amounts of THC are typically negligible, it is still a possibility that it will show up on a drug test.

Some drug tests can even show a false positive for THC in people who only use CBD. This can cause big issues for people like Mark Pennington, who lost custody of his son after a false THC positive

Lewis, Amanda Chicago. CBD or THC? Common Drug Test Can’t Tell the Difference. The New York Times. 15 Oct 2019.

It’s tricky because there is no standardization or quality control for CBD, which poses a risk for some products containing potentially unknown amounts of THC. The Food and Drug Administration (FDA) is currently in the process of forming CBD regulations to better address these issues.

Because of these risks, it’s a good idea to let your supervisor or HR department know about your CBD consumption if you are drug tested at work.

Is CBD Safe?

Just because CBD products from regulated sources are legal, it doesn’t mean they’re FDA-approved. The FDA has reservations about most CBD products, including CBD oil, on the market.

Their website states:

“Other than one prescription drug product [Epidiolex] to treat rare, severe forms of epilepsy, the FDA has not approved any other CBD products, and there is very limited available information about CBD, including about its effects on the body. The FDA is working to learn more about the safety of CBD and CBD products.”

CBD for Migraine: What the Research Says

The efficacy of CBD for Migraine is still unknown, but we do know it helps treat severe childhood epilepsy.

On June 25th, 2018, the FDA approved Epidiolex, the first and only prescription drug made from CBD isolate

Perucca E. Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?. J Epilepsy Res. 2017;7(2):61–76. Published 2017 Dec 31. doi:10.14581/jer.17012

A New Study on Migraine and Cannabis

Cathy Glaser, Executive Director of the Migraine Research Foundation, found the research lacking as she began to educate herself about medical marijuana.

“It is difficult to do research in this area because it’s still prohibited by the federal government, and individual states have different laws governing its use. Since little is known about the therapeutic effects of cannabis for Migraine, we don’t know which component, dose, or delivery method may be effective (or not),” explained Glaser.

The Migraine Research Foundation funded a study in 2018 to compare the efficacy of various components of vaped cannabis, including CBD and THC, for the acute treatment of Migraine attacks.

Dr. Nathaniel Schuster, a neurologist who specializes in headache and pain at UC San Diego, is leading the study.

“I’m studying vaporized [cannabis] for acute Migraine since for acute Migraine we want treatments that will get to the brain as quickly as possible. Non-oral Migraine treatments have long been part of our treatment of acute Migraine given that nausea is a common symptom of Migraine and that Migraine can slow down the gastrointestinal system.”

While he hopes to shed some much-needed light on CBD and Migraine, he urges caution.

“. there’s no medication out there that cures everything. The conditions that people are using CBD for deserve rigorous clinical research so that the public can know for which conditions CBD is effective and for which conditions CBD is not effective.”

Another study on CBD for Migraine is also in the works. Dr. Eric Baron and Dr. Ethan Russo will soon be launching a large clinical trial to evaluate CBD for Migraine prevention.

We hope these types of clinical trials will provide data, evidence, and clarification on CBD dosing for migraines.

The Bottom Line: Today there just isn’t enough evidence to determine if CBD can help prevent or treat migraine attacks. That’s why these new studies are so important.

What Current Research Says about CBD and Migraine Symptoms

While we know little about CBD and Migraine, there is some preliminary research on CBD for common Migraine symptoms like inflammation, pain, anxiety, and nausea.

CBD for Inflammation

In animal studies, inflammation has shown some response to CBD, according to a report by Harvard Medical School