Rub on cbd oil for seizures in adults

Cerebral Palsy and Medical Marijuana

This article has been fact checked by a Board Certified Pediatrician. Sources of information for the article are listed at the bottom.

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Cerebral palsy and medical marijuana might be useful in managing severe seizures and epilepsy. Research on the use of medical marijuana in cerebral palsy is still limited. Findings from some studies suggest that it offers a host of benefits, including pain control, reduction of spastic movements, reduction of seizures, and more.

Survey of Pain Treatment Study

In 2011, the results of a study on the treatment of pain in people with cerebral palsy were published by the National Institutes of Health (NIH). A total of 83 adults with cerebral palsy participated in the study, which consisted of trying 23 different medications for pain, including medical marijuana.[1]

The study reported the legs, lower back, and hips as the most common painful areas. According to the paper,

“The treatment that was rated as providing the most relief was marijuana; however, less than 5% of the sample reported ever using this drug for pain.”

Medical Marijuana and Spastic Quadriplegia

Spastic quadriplegia is the most severe form of cerebral palsy, affecting all extremities, the face, and the trunk. The majority of children with spastic quadriplegia cannot walk, and their speech is usually profoundly affected.

While the limbs can be extremely stiff, their neck muscles may be weak, making it difficult for them to hold their head up. Physical pain and communication problems are common in those with spastic quadriplegia.

Although more data are needed, the few studies conducted on the use of medical marijuana for spastic quadriplegia symptoms indicate that it offers numerous therapeutic benefits.

For example, a study published by the NIH in 2007 states that clinical experience and animal studies demonstrate that the active constituents in marijuana help to control partial seizures frequently seen in people with spastic quadriplegia.[2]

Another study published in 2014 showed marijuana to be effective in reducing painful muscle spasms. Although the study focused on people who experienced muscle spasms associated with multiple sclerosis, spasms are among the most common symptoms in people with cerebral palsy.[3]

Federal guidelines make it difficult for scientists to continue conducting in-depth research. However, many states now permit medical marijuana to be used to treat spasms and pain. Louisiana is the only state that allows its use specifically to treat spastic quadriplegia without a doctor’s referral.

Cannabis Oil (CBD)

Cannabis oil, or CBD oil, named after one of the many compounds found in marijuana, has gained popularity in recent years, especially after a special aired on CNN involving a young girl who once suffered from close to 50 convulsive seizures every day.

After exhausting every other possible option to help her, the girl’s parents turned to a formulation with a high concentration of CBD oil, now known as “Charlotte’s Web” after their daughter’s first name.[4]

Photo by Rhonda Prather

Charlotte’s parents titrated the CBD oil over several weeks while continuing the seizure treatment plan already in place. After weeks of using the oil, the frequency of Charlotte’s seizures went down to only two or three per day.

The CBD oil treatment became so successful that Charlotte eventually weaned off of her other anti-seizure medications. She also began walking, talking, and even riding her bicycle, things she had difficulty doing before. According to her father, Matt,

“I literally see Charlotte’s brain making connections that haven’t been made in years. My thought now is, why were we the ones that had to go out and find this cure? This natural cure? How come a doctor didn’t know about this? How come they didn’t make me aware of this?”

Charlotte’s mother, Page added,

“I didn’t hear her laugh for six months. I didn’t hear her voice at all, just her crying. I can’t imagine that I would be watching her making these gains that she’s making, doing the things that she’s doing (without the medical marijuana). I don’t take it for granted. Every day is a blessing.”

More and more companies are offering CBD oil as a treatment for children with cerebral palsy who experience seizures and muscle spasms, and chronic pain.

It’s important to thoroughly research companies and attempt to get your physician’s advice before deciding on any kind of medication. However, that state laws and even personal preferences may prohibit your child’s doctor from giving you a recommendation for CBD treatment.

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The Myth of “Getting High” and Medical Marijuana

One of the legitimate concerns of parents considering medical marijuana treatment for their children is the “getting high” factor. According to David Casarett, MD, author of Stoned: A Doctor’s Case For Medical Marijuana, THC is the compound in marijuana that’s responsible for producing the feeling of being high.[5]

The majority of medical marijuana and cannabis oil products have such a low concentration of THC that they do not produce a high. Medical marijuana and CBD oil generally contain a higher concentration of CBD. It is the CBD ingredient in marijuana that helps treat seizures and muscle spasms.

It’s THC that gets you high. If you feel euphoric, or if you’re unfortunate enough to have bad side effects (like hallucinations), those are due to THC. So marijuana probably will get you high as long as it’s got some THC in it. But, CBD, on the other hand, doesn’t have any of those brain effects. In fact, there have been studies using 300, 400, or 600 milligrams of CBD — which is a really whopping dose — with no psychological effects whatsoever.”

“So, if you’re using marijuana or marijuana products that are low in THC, then no, you won’t get high. That includes, most notably, the concentrated oils that are used [to treat] pediatric seizures.”

Speech Disorders and Medical Marijuana

Medical marijuana may also benefit those with cerebral palsy who have speech disorders and impediments, such as stuttering. Speech repetition and stuttering are frequently associated with cerebral palsy. Although these issues aren’t life-threatening, they can be extremely debilitating to people when they want to communicate more effectively.

Jacqueline Patterson has lived with cerebral palsy and a severe stuttering issue since she was a little girl. In 2007, she created a documentary entitled In Pot We Trust, where she detailed how marijuana not only helped reduce her speech problem significantly but also improved her severe muscle pain and stiffness.[6]

Unfortunately, Patterson used marijuana in Missouri, a state that doesn’t allow its use for any purpose, including medical indications. Consequently, her four children were taken away from her, but she took her case to Missouri representatives. While speaking to the group of legislators, she said,

For the first time, my muscles were not tense. And words slid from my mouth, from gggghhh — from me at a fluid pace instead of sssss-stuck on my tongue like a g-ghh — like a train wreck.”

Patterson didn’t have much success convincing the chairpersons that day that the medical use of marijuana was turning her health around and helping her family. She eventually moved to California along with her four children. She now advocates for marijuana as a treatment for people with cerebral palsy and other disorders.

There’s very little clinical research published on medical marijuana and stuttering, but numerous physicians in several states advocate its use as an effective treatment option for speech problems.

Talk to your child’s medical team before trying any marijuana-based medicine. There might be good reasons your child shouldn’t have it.

Lifelong Financial Assistance for Your Child’s Birth Injury Cerebral Palsy

References
  1. Survey Results of Pain Treatments in Adults with Cerebral Palsy. (2011, March). PubMed Central (PMC). National Institutes of Health.
    Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036542/
  2. Mortati K , et al. (2007). Marijuana: an effective antiepileptic treatment in partial epilepsy? A case report and review of the literature. – PubMed – NCBI. National Center for Biotechnology Information.
    Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/17609644
  3. Syed YY , et al. (n.d.). Delta-9-tetrahydrocannabinol/cannabidiol (Sativex®): a review of its use in patients with moderate to severe spasticity due to multiple sclerosis. – PubMed – NCBI. National Center for Biotechnology Information.
    Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/24671907
  4. By Saundra Young. (2013, August 7). Marijuana stops child’s severe seizures. CNN.
    Retrieved from: https://www.cnn.com/2013/08/07/health/charlotte-child-medical-marijuana/
  5. David Casarett’s Stoned: A Doctor’s Case for Medical Marijuana. (2016, March). PubMed Central (PMC).
    Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938260/
  6. Millitzer, J. (2013, December 9). Watch This: Smoking Medical Marijuana Transforms Woman with Cerebral Palsy. Fox 2.
    Retrieved from: https://fox2now.com/news/watch-this-smoking-medical-marijuana-transforms-woman-with-cerebal-palsy/
Page Medically Reviewed and Edited by Gina Jansheski, M.D.

Gina Jansheski, M.D. is a Board Certified Pediatrician and a Fellow of the American Academy of Pediatrics. She has been a practicing pediatrician for over 20 years, working primarily with hospitalized patients and children with special needs.

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13 Best CBD Oils for Seizures

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If you or someone you know has epilepsy, it’s likely that you have been looking for a natural way to control seizures. In this article, we will explore some of the best CBD oils available right now for treating epilepsy and seizure disorders.

CBD (cannabidiol) is one of many chemical compounds found in cannabis plants. It does not produce any psychoactive effects so it can be safely used by children, adults, and pets without fear of getting high or experiencing side effects.

These benefits aside, there are also numerous studies that show that CBD oil may help with anxiety and depression as well as chronic pain relief without the side effects associated with prescription medications like opioids.

As such, CBD oil is quickly becoming an ideal supplement for those who want to live a healthier and happier life.

What is CBD?

CBD, or cannabidiol, is one of the many active compounds found in cannabis plants. Although it is not psychoactive like THC (tetrahydrocannabinol), CBD has valuable health benefits that have recently attracted the attention of medical professionals around the world for treating conditions that were once deemed untreatable.

The reason why CBD is non-intoxicating is because it does not affect the same pathways as THC. This makes it a much better option for those who are looking to achieve therapeutic benefits without experiencing mind-altering effects that may interfere with their day-to-day tasks.

While research has not yet fully determined all of the health benefits of CBD, studies have shown that this compound is extremely safe, even at high dosages. Even so, most people who are looking for the benefits of CBD oil may not be aware of the best ways to use it for maximum therapeutic benefits.

Does CBD Oil Work for Seizures?

For those who are not aware, there are actually several types of seizures, all of which can be treated using CBD oil. The most well-known form is epilepsy, which occurs in the brain.

Based on some studies, we’ve learned that CBD does not act on the same pathways as THC, it is actually one of the most ideal options for treating seizures. CBD helps calm electrical and chemical activity in the brain to promote healthy neurological development, which helps prevent seizure attacks.

Of course, you should always talk to your doctor before adding CBD to your regimen. But whether you are looking for a safe alternative option or need relief from epilepsy, CBD oil has been found to be extremely effective as a treatment option with little to no side effects.

Are There Side Effects of CBD Oils?

CBD is no longer viewed as a dangerous and addictive drug like it once was many years ago. Today’s CBD products are non-intoxicating and comprised of natural ingredients that actually work with your endocannabinoid system instead of against it.

Even so, some people who are new to CBD oil may experience mild side effects like fatigue, dry mouth, and changes in appetite. If you notice any of these side effects when using CBD for seizures, it is best to only use the recommended dosage on your product’s packaging so you can adjust accordingly.

Today we’re sharing more about CBD oils for seizures to help you find maximum relief with a more natural product.

Cannabis oil for epilepsy – what you need to know

I have been approached by Dragonfly Biosciences who produce and market cannabidiol (CBD) to sit on their Advisory Panel. I do not receive funding from Dragonfly Biosciences, but would be paid a consultancy fee if I join the Advisory Boorad. My scientific publication support the use of non-THC cannabidinoids, as reflected in this article. I have previously received funding from GW Pharmaceuticals, but I am currently not in receipt of such funding.

Partners

University of Reading provides funding as a member of The Conversation UK.

Epilepsy drugs don’t work well, or at all, for about one-third of people with the condition. Unfortunately, these hard-to-treat epilepsies are associated with an increased risk of premature death.

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Anecdotal evidence suggests that cannabis oil may help some of these people control their seizures and potentially save their lives. A small number of studies have shown that adding cannabis oil to existing medication may be effective in devastating, hard-to-treat epilepsy in children and adolescents.

One of those people is 12-year-old Billy Caldwell. Billy was in the news recently after the cannabis oil prescribed for him was confiscated at Heathrow airport by the authorities. Billy’s mother, Charlotte, was attempting to bring the cannabis oil into the UK from Canada, where cannabis oil is legal.

Billy was seizure-free for more than 250 days when taking the oil, but his seizures started again when his cannabis oil was withdrawn. The home secretary, Sajid Javid, was persuaded to intervene and one of the seven bottles of cannabis oil was returned, with a 20-day licence to administer the medicine.

In a similar case, six-year-old Alfie Dingle, who suffers from severe epilepsy, had been successful treated with cannabis oil in the Netherlands. Alfie’s mother, Hannah Deacon, has been campaigning to allow her son to be provided with cannabis oil in the UK.

The government has now also relented in Alfie’s case following the concerns raised around the confiscation and return of Billy Caldwell’s medicine.

Home secretary, Sajid Javid, intervened in Billy Caldwell case and returned a bottle of cannabis oil. EPA/Andy Rain

What the evidence shows

So what do we know about cannabis oil and its effects on epilepsy seizures?

The two main constituents of cannabis oil are THC (tetrahydrocannabinol) and CBD (cannabidiol). Oil containing CBD alone (CBD oil) can be legally bought in the UK without a prescription because it contains only very low quantities of THC. But cannabis oil that contains THC at higher levels (more than 0.3%) is illegal. THC is a schedule 1 drug, that is to say, it is deemed to have no medicinal value.

The reason that Billy’s cannabis oil was seized at Heathrow airport was that it didn’t just contain CBD, it also contained THC at higher levels than legally permitted.

There is good evidence in robust human clinical trials that CBD is of benefit for specific epilepsies, such as Dravet syndrome and Lennox Gastaut syndrome. An advantage for the pharmaceutical industry is that these rare diseases with no cure can be fast-tracked for drug development. On this basis, the US Food and Drug Administration is widely expected to grant a licence for CBD (under the tradename Epidiolex) to treat these epilepsies. If so, Epidiolex is likely to be available in US by late 2018. European approval is likely to follow.

It should be noted that Epidiolex is designed as standardised oral solution of pure plant-derived CBD. It is not the same as the non-standardised, viscous CBD oils that contain varying amounts of CBD and can be purchased in health food shops. There is currently no good evidence that formulations of CBD oil (or indeed cannabis oil) are as effective on epilepsy seizures. Equally, there is no robust evidence – just anecdotal reports – that THC helps reduce epilepsy seizures human.

In [animal studies], THC has weak overall effects in reducing seizures and has also been shown to be a less effective anticonvulsant than CBD. THC, being a psychoactive substance, also has a number of side effects, including the well-known euphoric “high” associated with recreational use – which is a significant disincentive for the pharmaceutical industry to develop a medicine containing this compound.

We now need to decide if we should expand human trials with better defined THC-containing cannabis oil, or if we should focus on CBD. The fact that Epidiolex has progressed towards approval in the US may encourage the latter course. CBD lacks psychoactive effects associated with THC and, in general, is regarded as a safe compound.

If Epidiolex is granted regulatory approval, it will also need to be monitored in a larger number of patients – in what’s known as “phase 4 post-marketing surveillance” – to ensure that it is safe and effective in a broader population. For any cannabis-based product, only large-scale clinical trials can provide definitive answers about effectiveness and safety.